Results 61 to 70 of about 14,956 (188)

Piperazines for peptide carboxyl group derivatization: effect of derivatization reagents and properties of peptides on signal enhancement in matrix-assisted laser desorption ionization mass spectrometry

, 2011
Piperazines for peptide carboxyl group derivatization: effect of derivatization reagents and properties of peptides on signal enhancement in matrix-assisted laser desorption/ionization mass ...
梁振, 张玉奎, 杨开广, 乔晓强, 陈令凡, 周愿, 孙良亮, 张丽华   +7 more
core  

Visible Light-Mediated, Diastereoselective Epimerization of Morpholines and Piperazines to More Stable Isomers

, 2022
We report a photocatalyzed epimerization of morpholines and piperazines that proceeds by reversible hydrogen atom transfer (HAT) and provides an efficient strategy for editing the stereochemical configurations of these saturated nitrogen heterocycles ...
Zican Shen (5931245), Jonathan A. Ellman (610362), Elizabeth L. Rigby (13932517), Shuming Chen (1590061), María A. Vargas-Rivera (13932514)   +4 more
core   +1 more source

Synthesis and antimicrobial activity of carbonyl pyridoquinolones containing urea and piperazine residue

Journal of Saudi Chemical Society, 2010
In the present work, carbonyl pyridoquinolones 8–33 were synthesized and their ability to inhibit gram-positive stains Bacillus subtilis and Staphylococcus aureus, gram-negative stains Escherichia coli and Pseudomonas aeruginosa, and fungi Candida ...
Navin B. Patel, Jaymin C. Patel, Sandip H. Modi   +2 more
doaj   +1 more source

Thioxopyrimidine in Heterocyclic Synthesis I: Synthesis of Some Novel 6-(Heteroatom-substituted)-(thio)pyrimidine Derivatives

Journal of Chemistry, 2013
A series of novel N-cycloalkanes, morpholine, piperazines, pyrazole, pyrimidine, benzimidazolo[1,2-a]pyrimidine, 1,2,3,4-tetrazolo[1,5-a]pyrimidine, azopyrazolo[1,5- a]pyrimidine, pyrimido[4', 5':3,4]pyrazolo[1,5-a]pyrimidines and pyridine derivatives ...
Yuh-Wen Ho, Maw Cherng Suen
doaj   +1 more source

Development of a targeted GC/MS screening method and validation of an HPLC/DAD quantification method for piperazines–amphetamines mixtures in seized material

Egyptian Journal of Forensic Sciences, 2014
Piperazine-related drugs are sold as party pills in the form of tablets, capsules, liquids or powders. These party pills can contain several piperazine derivatives, or even a mixture of piperazines and amphetamine derivatives.
Yacine Boumrah, Martine Rosset, Yannick Lecompte, Sabrina Bouanani, Kamel Khimeche, Abdellah Dahmani   +5 more
doaj   +1 more source

Complete Regioselective Addition of Grignard Reagents to Pyrazine N-Oxides, Toward an Efficient Enantioselective Synthesis of Substituted Piperazines

, 2016
A conceptually new one-pot strategy for the synthesis of protected substituted piperazines via the addition of Grignard reagents to pyrazine N-oxides is presented. This strategy is high yielding (33−91% over three steps), step-efficient, and fast.
Roger Olsson (1399453), Hans Andersson (2007136), Fredrik Almqvist (698391), Thomas Sainte-Luce Banchelin (2007142), Magnus Gustafsson (2290414), Sajal Das (805163)   +5 more
core   +1 more source

MC19 (M = B, Si, Al and Ga) fullerenes: Adsorption mechanisms of 1,4-diformylpiperazine

Adsorption Science & Technology, 2018
Fullerenes and piperazines have been investigated, particularly, in the field of nanoscience and medicinal chemistry. In the present research, besides discussing structural and electronic properties, the most probable interaction mechanisms between C20 ...
Özgür Alver, Cemal Parlak, Ponnadurai Ramasami   +2 more
doaj   +1 more source

“High-Throughput” Evaluation of Polymer-Supported Triazolic Appendages for Metallic Cations Extraction

Metals, 2015
The aim of this work was to find and use a low-cost high-throughput method for a quick primary evaluation of several metal extraction by substituted piperazines appendages as chelatants grafted onto Merrifield polymer using click-chemistry by the ...
Riadh Slimi, Christian Girard
doaj   +1 more source

A Practical Synthesis of Differentially Protected 2-(Hydroxymethyl)piperazines

, 2016
An efficient and scalable synthesis of three differentially protected 2-(hydroxymethyl)piperazines is presented, starting from optically active and commercially available (2S)-piperazine-2-carboxylic acid dihydrochloride.
Hongwu Gao (2471113), Adam R. Renslo (114387)   +1 more
core   +1 more source

Discovery of a novel piperazine derivative, cmp2: a selective TRPC6 activator suitable for treatment of synaptic deficiency in Alzheimer’s disease hippocampal neurons

Scientific Reports
Alzheimer disease (AD) is characterized by progressive loss of memory. Synaptic loss is now the best correlate of cognitive dysfunction in patients with Alzheimer’s disease.
Nikita Zernov, Viktor Ghamaryan, Daria Melenteva, Ani Makichyan, Lernik Hunanyan, Elena Popugaeva   +5 more
doaj   +1 more source