Results 41 to 50 of about 39,960 (300)
Piperazine-2,3,5,6-tetraone [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 The mol-ecule of the title compound, C(4)H(2)N(2)O(4), is located around an inversion center and the four O atoms are in the 2,3,5,6-positions of the piperazine ring. In the crystal, bifurcated N-H⋯O hydrogen bonds link the mol-ecules into a corrugated layer parallel to (101).
Yi-Min Jiang +4 more
openaire +3 more sources
Synthesis of oxetane- and azetidine-containing spirocycles related to the 2,5-diketopiperazine framework [PDF]
, 2015 A simple two-step sequence is used to efficiently make novel spirocyclic analogues of the diketopiperazine nucleus. Conjugate addition of chiral α-amino esters to nitroalkenes, generated from oxetan-3-one or N-Boc-azetidin-3-one, followed by nitro group ...
Beadle, Jonathan D. +4 more
core +1 more source
Research Progress on Detection of New Psychoactive Substance Piperazines in vivo
Fayixue ZazhiPiperazines are a class of new psychoactive substances with hallucinogenic effects that affect the central nervous system by affecting the level of monoamine neurotransmitters.
LIU Jin-ting +6 more
doaj +1 more source
Molecules, 2020 A three-component reaction between diamines (diaminobenzenes, diaminocyclohexanes, and piperazines), triethyl orthoformate, and diethyl phosphite was studied in some detail.
Patrycja Petruczynik +6 more
doaj +1 more source
Increases in use of novel synthetic stimulant are not directly linked to decreased use of 3,4-methylenedioxy-N-methylamphetamine (MDMA) [PDF]
, 2013 A decline in 3,4-methylenedioxy-N-methylamphetamine (MDMA) use in Adelaide, Australia from 2009 to 2010 was confirmed by us previously. Reports suggested that the shortage in MDMA supply was associated with an increased prevalence of other synthetic ...
Chen, C. +3 more
core +1 more source
Synthesis and pharmacological evaluation of several N-(2-nitrophenyl)piperazine derivatives [PDF]
Journal of the Serbian Chemical Society, 2007 Six newly synthesized heterocyclic (2-nitrophenyl)piperazines, with a specific structure of the heteroaryl group, whichmimics the catechol moiety of dopamine (benzimidazoles and substituted benzimidazoles), were evaluated for their binding affinity to ...
DEANA ANDRIC +6 more
doaj +3 more sources
Recent changes in drug abuse scenarios : The new/novel psychoactive substances (NPS) phenomenon [PDF]
, 2018 © 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Peer ...
Schifano, Fabrizio
core +2 more sources
Chinese journal of chemistryA catalyst‐free and additive‐free ring‐opening reaction of polyfluoroalkyl peroxides, triethylenediamine (DABCO), and 1,2‐dichloroethane (DCE) has been developed for the defluorinative synthesis of structurally diverse piperazines featuring a fluoroenone
Yuan-Yuan Ren +6 more
semanticscholar +1 more source
Substituted Piperazines as Novel Potential Radioprotective Agents
Molecules, 2020 The increasing risk of radiation exposure underlines the need for novel radioprotective agents. Hence, a series of novel 1-(2-hydroxyethyl)piperazine derivatives were designed and synthesized. Some of the compounds protected human cells against radiation-
Alzbeta Filipova +15 more
doaj +1 more source
Pharmacology of novel psychoactive substances [PDF]
, 2016 This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core +1 more source