Results 41 to 50 of about 15,176 (256)

Synthesis and pharmacological evaluation of several N-(2-nitrophenyl)piperazine derivatives [PDF]

open access: yesJournal of the Serbian Chemical Society, 2007
Six newly synthesized heterocyclic (2-nitrophenyl)piperazines, with a specific structure of the heteroaryl group, whichmimics the catechol moiety of dopamine (benzimidazoles and substituted benzimidazoles), were evaluated for their binding affinity to ...
DEANA ANDRIC   +6 more
doaj   +3 more sources

SnAP Reagents for the Synthesis of Piperazines and Morpholines

open access: yes, 2016
Substituted piperazines and morpholines are valuable structural motifs in biologically active compounds, but are not easily prepared by contemporary cross-coupling approaches. In this report, we introduce SnAP reagents for the transformation of aldehydes
Cam-Van T. Vo (1843522)   +2 more
core   +2 more sources

Substituted Piperazines as Novel Potential Radioprotective Agents

open access: yesMolecules, 2020
The increasing risk of radiation exposure underlines the need for novel radioprotective agents. Hence, a series of novel 1-(2-hydroxyethyl)piperazine derivatives were designed and synthesized. Some of the compounds protected human cells against radiation-
Alzbeta Filipova   +15 more
doaj   +1 more source

Twelve 4-(4-methoxyphenyl)piperazin-1-ium salts containing organic anions: supramolecular assembly in one, two and three dimensions

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2019
Twelve 4-(4-methoxyphenyl)piperazin-1-ium salts containing organic anions have been prepared and structurally characterized. The monohydrated benzoate, 4-fluorobenzoate, 4-chlorobenzoate and 4-bromobenzoate salts, C11H17N2O+·C7H5O2−·H2O (I), C11H17N2O ...
Haruvegowda Kiran Kumar   +3 more
doaj   +1 more source

Synthesis, biological evaluation and docking analysis of substituted piperidines and (2-methoxyphenyl)piperazines [PDF]

open access: yesJournal of the Serbian Chemical Society, 2016
A series of sixteen novel substituted piperidines and (2-methoxyphenyl)piperazines were synthesized, starting from the key intermediates 1-(2-methoxyphenyl)-4-(piperidin-4-yl)piperazine and 1-(2-methoxyphenyl)-4-(piperidin-4-ylmethyl)piperazine.
Penjišević Jelena Z.   +6 more
doaj   +1 more source

Diastereoselective Synthesis of Piperazines by Manganese-Mediated Reductive Cyclization

open access: yes, 2016
A simple and effective synthesis of trans aryl-substituted piperazines using a Brønsted acid and manganese(0) is ...
Matthew S. Sigman (1306671)   +1 more
core   +1 more source

Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles [PDF]

open access: yes, 2023
We report a heterocyclic merging approach to construct novel indazolo-piperazines and indazolo-morpholines. Starting from chiral diamines and amino alcohols, novel regiochemically (1,3 and 1,4) and stereochemically diverse (relative and absolute) cohorts
Viveki, Amol B   +13 more
core   +1 more source

Synthesis and Anticonvulsant Activity of Some Quinazolin-4-(3H)-one Derivatives

open access: yesMolecules, 2008
A number of 3-substituted-2-(substituted-phenoxymethyl) quinazolin-4(3H)-one derivatives 4a,b, 5a-c, 6, 7a-f, 8a-e and 9a,b have been synthesized. Their structures have been elucidated on the basis of elemental analyses and spectroscopic studies (IR, 1H ...
Safinaz Abbas   +2 more
doaj   +1 more source

Recent advances in photocatalytic hydrogen peroxide production

open access: yesPhotoMat, EarlyView., 2023
We classify the representative photocatalytic materials for photosynthesis of hydrogen peroxide (H2O2) in recent years and discuss the related modification methods in detail, providing inspiration and insights for the future design of photocatalysts for H2O2 production.
Jinyu Yan   +4 more
wiley   +1 more source

A structural study of 2,4-dimethylaniline derivatives

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2018
Crystallographic studies of nitrogen-containing small molecules aid in the elucidation of their structure–activity relationships and modes of aggregation.
Samuel C. Penner   +2 more
doaj   +1 more source

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