Results 41 to 50 of about 14,956 (188)

SC-XRD diffraction images of stereo-defined piperazines (1/2)

open access: yes, 2017
<p>Structures of two piperazines in the publication: Suarez-Pantiga, S.; Colas, K.; Johansson, M. J.; Mendoza, A.* "Scalable synthesis of piperazines enabled by visible light irradiation and aluminum organometallics" <br> Angew. Chem. Int. Ed.
Colas, Kilian   +7 more
core   +1 more source

Synthesis of novel antibacterial and antifungal dithiocarbamate-containing piperazine derivatives via re-engineering multicomponent approach

open access: yesHeliyon, 2022
A metal-free multicomponent synthetic route for the diverse preparation of dithiocarbamate-containing piperazine derivatives was developed through the C–N bond cleavage of DABCO ring.
Azim Ziyaei Halimehjani   +5 more
doaj   +1 more source

Iridium catalysed synthesis of piperazines from diols

open access: yes, 2007
A green and atom-economical method has been developed for the synthesis of piperazines by cyclocondensation of diols and amines in aqueous media in the presence of a catalytic amount of [Cp*IrCl2 ...
Madsen, Robert   +1 more
core   +1 more source

Diastereoselective Synthesis of Piperazines by Manganese-Mediated Reductive Cyclization

open access: yes, 2016
A simple and effective synthesis of trans aryl-substituted piperazines using a Brønsted acid and manganese(0) is ...
Matthew S. Sigman (1306671)   +1 more
core   +1 more source

Piperazine Abuse and Psychosis: A Systematic Review of the Literature

open access: yesPsychiatry International
Background: Piperazines, synthetic compounds known for their stimulant and hallucinogenic effects, have gained prominence among novel psychoactive substances (NPS) and are frequently associated with adverse psychiatric outcomes, including psychosis ...
Alessio Mosca   +9 more
doaj   +1 more source

4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues. [PDF]

open access: yesPLoS ONE, 2017
Our ability to use ionizing radiation as an energy source, as a therapeutic agent, and, unfortunately, as a weapon, has evolved tremendously over the past 120 years, yet our tool box to handle the consequences of accidental and unwanted radiation ...
Ewa D Micewicz   +17 more
doaj   +1 more source

Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides

open access: yes, 2016
A facile method has been developed for the synthesis of chiral piperazines through Ir-catalyzed hydrogenation of pyrazines activated by alkyl halides, giving a wide range of chiral piperazines including 3-substituted as well as 2,3- and 3,5-disubstituted
Wen-Xue Huang (1626910)   +11 more
core   +1 more source

Synthesis and Antimicrobial Activity of Some Novel Substituted Piperazinyl-quinazolin-3(4H)-ones

open access: yesE-Journal of Chemistry, 2008
Several substituted-quinazolin-3(4H)-ones were synthesized by condensation of 2-chloro-N-(4-oxo-substituted-quinazolin-3(4H)-yl)-acetamides with various substituted piperazines through single step reaction. Elemental analysis, IR, 1HNMR and mass spectral
N. M. Raghavendra   +2 more
doaj   +1 more source

Diastereoselective Synthesis of 2‑Phenyl-3-(trifluoromethyl)piperazines as Building Blocks for Drug Discovery

open access: yes, 2016
The synthesis of enantiomerically pure cis- and trans-2-phenyl-3-(trifluoromethyl)­piperazines is described. It involved, as the key step, a diastereoselective nucleophilic addition of the Ruppert–Prakash reagent (TMSCF3) to α-amino sulfinylimines ...
Santos Fustero (1330944)   +5 more
core   +1 more source

Designer drugs: aspectos analíticos e biológicos

open access: yesQuímica Nova, 2012
In the recent years, analytical toxicologists have been facing difficulties in detecting designer drugs due to the chemical modifications on the existing structures and the speed in which they are released into the market, requiring the development and ...
Rachel Bulcão   +7 more
doaj   +1 more source

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