Results 31 to 40 of about 15,176 (256)

Crystal structure of 2-(4-methylpiperazin-1-yl)quinoline-3-carbaldehyde

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C15H17N3O, the aldehyde group is twisted relative to the quinoline group by17.6 (2)° due to the presence of a bulky piperazinyl group in the ortho position.
R Nivedita Desai, S Sreenivasa, S. Naveen, N. K. Lokanath, P. A. Suchetan, D. B. Aruna Kumar   +5 more
doaj   +1 more source

Piperazine Hepatitis

Gastroenterology, 1976
The first reported case of piperazine toxicity resembling viral hepatitis is described in a 25-year-old woman. The illness, which was severe, occurred after administration of the drug on two separate occasions. The evidence favors a hypersensitivity mechanism rather than a direct toxic effect of piperazine or its metabolites on the liver.
A N, Hamlyn, J S, Morris, I, Sarkany, S, Sherlock   +3 more
openaire   +2 more sources

Three closely related 1-[(1,3-benzodioxol-5-yl)methyl]-4-(halobenzoyl)piperazines: similar molecular structures but different intermolecular interactions

Acta Crystallographica Section E: Crystallographic Communications, 2019
In each of the compounds 1-[(1,3-benzodioxol-5-yl)methyl]-4-(3-fluorobenzoyl)piperazine, C19H19FN2O3 (I), 1-[(1,3-benzodioxol-5-yl)methyl]-4-(2,6-difluorobenzoyl)piperazine, C19H18F2N2O3 (II), and 1-[(1,3-benzodioxol-5-yl)methyl]-4-(2,4-dichlorobenzoyl ...
Ninganayaka Mahesha, Belakavadi K. Sagar, Hemmige S. Yathirajan, Tetsundo Furuya, Tomoyuki Haraguchi, Takashiro Akitsu, Christopher Glidewell   +6 more
doaj   +1 more source

Six 1-aroyl-4-(4-methoxyphenyl)piperazines: similar molecular structures but different patterns of supramolecular assembly

Acta Crystallographica Section E: Crystallographic Communications, 2019
Six new 1-aroyl-4-(4-methoxyphenyl)piperazines have been prepared, using coupling reactions between benzoic acids and N-(4-methoxyphenyl)piperazine.
Haruvegowda Kiran Kumar, Hemmige S. Yathirajan, Belakavadi K. Sagar, Sabine Foro, Christopher Glidewell   +4 more
doaj   +1 more source

Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring

Pharmaceuticals, 2023
Arylpiperazines represent one of the most important classes of 5-HT1AR ligands and have attracted considerable interests for their versatile properties in chemistry and pharmacology, leading to the research of new derivatives that has been focused on the
Giorgia Andreozzi, Maria Rosaria Ambrosio, Elisa Magli, Giovanni Maneli, Beatrice Severino, Angela Corvino, Rosa Sparaco, Elisa Perissutti, Francesco Frecentese, Vincenzo Santagada, Anna Leśniak, Magdalena Bujalska-Zadrożny, Giuseppe Caliendo, Pietro Formisano, Ferdinando Fiorino   +14 more
doaj   +1 more source

CO2 Capture with Silylated Ethanolamines and Piperazines

ChemistryOpen, 2020
Invited for this month's cover is the group of Marcus Herbig from the TU Bergakademie in Freiberg. The cover picture shows the reaction of CO2 with a silyl derivative of the biogenic amine ethanolamine.
Marcus Herbig, Lia Gevorgyan, Moritz Pflug, Dr. Jörg Wagler, Dr. Sandra Schwarzer, Prof. Edwin Kroke   +5 more
doaj   +2 more sources

Synthesis, and Antitumor Activity of Some N1-(Coumarin-7-yl) Amidrazones and Related Congeners

Molecules, 2011
A series of new N1-(coumarin-7-yl)amidrazones incorporating N-piperazines and related congeners were synthesized by reacting the hydrazonoyl chloride derived from 7-amino-4-methylcoumarin with the appropriate piperazines.
Mohammad S. Mustafa, Mustafa M. El-Abadelah, Malek A. Zihlif, Randa G. Naffa, Mohammad S. Mubarak   +4 more
doaj   +1 more source

Research Progress on Detection of New Psychoactive Substance Piperazines in vivo

Fayixue Zazhi
Piperazines are a class of new psychoactive substances with hallucinogenic effects that affect the central nervous system by affecting the level of monoamine neurotransmitters.
LIU Jin-ting, ZHOU Li-ying, XIANG Jia-hong, LI Zi-yi, XIE Wan-ting, YUN Ke-ming, SHI Yan   +6 more
doaj   +1 more source

Three-Component Reaction of Diamines with Triethyl Orthoformate and Diethyl Phosphite and Anti-Proliferative and Antiosteoporotic Activities of the Products

Molecules, 2020
A three-component reaction between diamines (diaminobenzenes, diaminocyclohexanes, and piperazines), triethyl orthoformate, and diethyl phosphite was studied in some detail.
Patrycja Petruczynik, Paweł Kafarski, Mateusz Psurski, Joanna Wietrzyk, Zdzisław Kiełbowicz, Jan Kuryszko, Ewa Chmielewska   +6 more
doaj   +1 more source

Efficient synthesis of spirooxindole-pyrrolizidines and dispirooxindole-piperazines

, 2018
A simple and efficient approach for the construction of spirooxindole-pyrrolizidines and dispirooxindole-piperazines by cycloaddition reaction of azomethine ylide generated by isatin and proline has been demonstrated successfully.
Keshri Nath Tiwari (2155438), P. Sreelekha (4914808), Taur Prakash Pandurang (4914811), Suyash Pant (4914814)   +3 more
core   +1 more source