Results 31 to 40 of about 14,956 (188)

Efficient synthesis of spirooxindole-pyrrolizidines and dispirooxindole-piperazines

open access: yes, 2018
A simple and efficient approach for the construction of spirooxindole-pyrrolizidines and dispirooxindole-piperazines by cycloaddition reaction of azomethine ylide generated by isatin and proline has been demonstrated successfully.
Keshri Nath Tiwari (2155438)   +3 more
core   +1 more source

Synthesis and pharmacological evaluation of several N-(2-nitrophenyl)piperazine derivatives [PDF]

open access: yesJournal of the Serbian Chemical Society, 2007
Six newly synthesized heterocyclic (2-nitrophenyl)piperazines, with a specific structure of the heteroaryl group, whichmimics the catechol moiety of dopamine (benzimidazoles and substituted benzimidazoles), were evaluated for their binding affinity to ...
DEANA ANDRIC   +6 more
doaj   +3 more sources

Substituted Piperazines as Novel Potential Radioprotective Agents

open access: yesMolecules, 2020
The increasing risk of radiation exposure underlines the need for novel radioprotective agents. Hence, a series of novel 1-(2-hydroxyethyl)piperazine derivatives were designed and synthesized. Some of the compounds protected human cells against radiation-
Alzbeta Filipova   +15 more
doaj   +1 more source

Twelve 4-(4-methoxyphenyl)piperazin-1-ium salts containing organic anions: supramolecular assembly in one, two and three dimensions

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2019
Twelve 4-(4-methoxyphenyl)piperazin-1-ium salts containing organic anions have been prepared and structurally characterized. The monohydrated benzoate, 4-fluorobenzoate, 4-chlorobenzoate and 4-bromobenzoate salts, C11H17N2O+·C7H5O2−·H2O (I), C11H17N2O ...
Haruvegowda Kiran Kumar   +3 more
doaj   +1 more source

Synthesis, biological evaluation and docking analysis of substituted piperidines and (2-methoxyphenyl)piperazines [PDF]

open access: yesJournal of the Serbian Chemical Society, 2016
A series of sixteen novel substituted piperidines and (2-methoxyphenyl)piperazines were synthesized, starting from the key intermediates 1-(2-methoxyphenyl)-4-(piperidin-4-yl)piperazine and 1-(2-methoxyphenyl)-4-(piperidin-4-ylmethyl)piperazine.
Penjišević Jelena Z.   +6 more
doaj   +1 more source

Synthesis and Anticonvulsant Activity of Some Quinazolin-4-(3H)-one Derivatives

open access: yesMolecules, 2008
A number of 3-substituted-2-(substituted-phenoxymethyl) quinazolin-4(3H)-one derivatives 4a,b, 5a-c, 6, 7a-f, 8a-e and 9a,b have been synthesized. Their structures have been elucidated on the basis of elemental analyses and spectroscopic studies (IR, 1H ...
Safinaz Abbas   +2 more
doaj   +1 more source

A structural study of 2,4-dimethylaniline derivatives

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2018
Crystallographic studies of nitrogen-containing small molecules aid in the elucidation of their structure–activity relationships and modes of aggregation.
Samuel C. Penner   +2 more
doaj   +1 more source

Silicon Amine Reagents for the Photocatalytic Synthesis of Piperazines from Aldehydes and Ketones

open access: yes, 2016
Silicon amine protocol (SLAP) reagents for photocatalytic cross-coupling with aldehydes and ketones to form N-unprotected piperazines have been developed.
Bode, Jeffrey W.   +5 more
core   +2 more sources

Surface-enhanced Raman spectroscopy (SERS) for the qualitative analysis of synthetic piperazines [PDF]

open access: yes, 2017
Designer drugs are some of the most commonly abused substances in the world. They are synthesized through slight chemical modifications of existing substances, evading the law while maintaining the desired effects of the pharmaceutical or illicit ...
Ward, Jessamyn
core   +1 more source

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