Results 21 to 30 of about 14,956 (188)
Gastroenterology, 1976 The first reported case of piperazine toxicity resembling viral hepatitis is described in a 25-year-old woman. The illness, which was severe, occurred after administration of the drug on two separate occasions. The evidence favors a hypersensitivity mechanism rather than a direct toxic effect of piperazine or its metabolites on the liver.
A N, Hamlyn +3 more
openaire +2 more sources
SnAP Reagents for the Synthesis of Piperazines and Morpholines
, 2016 Substituted piperazines and morpholines are valuable structural motifs in biologically active compounds, but are not easily prepared by contemporary cross-coupling approaches. In this report, we introduce SnAP reagents for the transformation of aldehydes
Cam-Van T. Vo (1843522) +2 more
core +2 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2019 In each of the compounds 1-[(1,3-benzodioxol-5-yl)methyl]-4-(3-fluorobenzoyl)piperazine, C19H19FN2O3 (I), 1-[(1,3-benzodioxol-5-yl)methyl]-4-(2,6-difluorobenzoyl)piperazine, C19H18F2N2O3 (II), and 1-[(1,3-benzodioxol-5-yl)methyl]-4-(2,4-dichlorobenzoyl ...
Ninganayaka Mahesha +6 more
doaj +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2019 Six new 1-aroyl-4-(4-methoxyphenyl)piperazines have been prepared, using coupling reactions between benzoic acids and N-(4-methoxyphenyl)piperazine.
Haruvegowda Kiran Kumar +4 more
doaj +1 more source
Pharmaceuticals, 2023 Arylpiperazines represent one of the most important classes of 5-HT1AR ligands and have attracted considerable interests for their versatile properties in chemistry and pharmacology, leading to the research of new derivatives that has been focused on the
Giorgia Andreozzi +14 more
doaj +1 more source
CO2 Capture with Silylated Ethanolamines and Piperazines
ChemistryOpen, 2020 Invited for this month's cover is the group of Marcus Herbig from the TU Bergakademie in Freiberg. The cover picture shows the reaction of CO2 with a silyl derivative of the biogenic amine ethanolamine.
Marcus Herbig +5 more
doaj +2 more sources
Synthesis, and Antitumor Activity of Some N1-(Coumarin-7-yl) Amidrazones and Related Congeners
Molecules, 2011 A series of new N1-(coumarin-7-yl)amidrazones incorporating N-piperazines and related congeners were synthesized by reacting the hydrazonoyl chloride derived from 7-amino-4-methylcoumarin with the appropriate piperazines.
Mohammad S. Mustafa +4 more
doaj +1 more source
Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles [PDF]
, 2023 We report a heterocyclic merging approach to construct novel indazolo-piperazines and indazolo-morpholines. Starting from chiral diamines and amino alcohols, novel regiochemically (1,3 and 1,4) and stereochemically diverse (relative and absolute) cohorts
Viveki, Amol B +13 more
core +1 more source
Research Progress on Detection of New Psychoactive Substance Piperazines in vivo
Fayixue ZazhiPiperazines are a class of new psychoactive substances with hallucinogenic effects that affect the central nervous system by affecting the level of monoamine neurotransmitters.
LIU Jin-ting +6 more
doaj +1 more source
Molecules, 2020 A three-component reaction between diamines (diaminobenzenes, diaminocyclohexanes, and piperazines), triethyl orthoformate, and diethyl phosphite was studied in some detail.
Patrycja Petruczynik +6 more
doaj +1 more source