Results 51 to 60 of about 37,689 (286)

Three-Component Reaction of Diamines with Triethyl Orthoformate and Diethyl Phosphite and Anti-Proliferative and Antiosteoporotic Activities of the Products

Molecules, 2020
A three-component reaction between diamines (diaminobenzenes, diaminocyclohexanes, and piperazines), triethyl orthoformate, and diethyl phosphite was studied in some detail.
Patrycja Petruczynik, Paweł Kafarski, Mateusz Psurski, Joanna Wietrzyk, Zdzisław Kiełbowicz, Jan Kuryszko, Ewa Chmielewska   +6 more
doaj   +1 more source

Efficient synthesis of spirooxindole-pyrrolizidines and dispirooxindole-piperazines

, 2018
A simple and efficient approach for the construction of spirooxindole-pyrrolizidines and dispirooxindole-piperazines by cycloaddition reaction of azomethine ylide generated by isatin and proline has been demonstrated successfully.
Keshri Nath Tiwari (2155438), P. Sreelekha (4914808), Taur Prakash Pandurang (4914811), Suyash Pant (4914814)   +3 more
core   +1 more source

Substituted Piperazines as Novel Potential Radioprotective Agents

Molecules, 2020
The increasing risk of radiation exposure underlines the need for novel radioprotective agents. Hence, a series of novel 1-(2-hydroxyethyl)piperazine derivatives were designed and synthesized. Some of the compounds protected human cells against radiation-
Alzbeta Filipova, Jan Marek, Radim Havelek, Jaroslav Pejchal, Marcela Jelicova, Jana Cizkova, Martina Majorosova, Lubica Muckova, Tomas Kucera, Lukas Prchal, Miroslav Psotka, Natalie Zivna, Darja Koutova, Zuzana Sinkorova, Martina Rezacova, Ales Tichy   +15 more
doaj   +1 more source

1,2‐Dichloroethane‐Assisted Defluorinative Ring‐Opening Reaction of DABCO and Polyfluoroalkyl Peroxides: Synthesis of Fluorinated N‐Ethyl Piperazines

Chinese journal of chemistry
A catalyst‐free and additive‐free ring‐opening reaction of polyfluoroalkyl peroxides, triethylenediamine (DABCO), and 1,2‐dichloroethane (DCE) has been developed for the defluorinative synthesis of structurally diverse piperazines featuring a fluoroenone
Yuan-Yuan Ren, Wen-Jun Ji, Chi Zhang, Danhua Ge, Mengtao Ma, Zhi‐Liang Shen, Xue‐Qiang Chu   +6 more
semanticscholar   +1 more source

Palladacarboxamide Capping Reagents for Carbon Isotope Labeling and Pharmaceutical Diversification

Angewandte Chemie, EarlyView.
Herein, we present a method for carbon isotope labeling of arylamides via the coupling of air‐stable palladium carboxamide complexes and boronic ester/acids. A wide variety of functionalized boronic esters and acids have been coupled with simple palladium carboxamides complexes.
Daniel V. Hoffmann, Anika Schick, Lasse Kjær, Vitus J. Enemærke, Clemens Kaussler, Jens Torp, Pablo Martínez‐Pardo, Charles S. Elmore, Troels Skrydstrup   +8 more
wiley   +2 more sources

Synthesis and pharmacological evaluation of several N-(2-nitrophenyl)piperazine derivatives [PDF]

Journal of the Serbian Chemical Society, 2007
Six newly synthesized heterocyclic (2-nitrophenyl)piperazines, with a specific structure of the heteroaryl group, whichmimics the catechol moiety of dopamine (benzimidazoles and substituted benzimidazoles), were evaluated for their binding affinity to ...
DEANA ANDRIC, GORDANA TOVILOVIC, GORAN ROGLIC, DJURDJICA VASKOVIC, VUKIC SOSKIC, MIRKO TOMIC, SLADJANA KOSTIC-RAJACIC   +6 more
doaj   +3 more sources

Twelve 4-(4-methoxyphenyl)piperazin-1-ium salts containing organic anions: supramolecular assembly in one, two and three dimensions

Acta Crystallographica Section E: Crystallographic Communications, 2019
Twelve 4-(4-methoxyphenyl)piperazin-1-ium salts containing organic anions have been prepared and structurally characterized. The monohydrated benzoate, 4-fluorobenzoate, 4-chlorobenzoate and 4-bromobenzoate salts, C11H17N2O+·C7H5O2−·H2O (I), C11H17N2O ...
Haruvegowda Kiran Kumar, Hemmige S. Yathirajan, Sabine Foro, Christopher Glidewell   +3 more
doaj   +1 more source

Synthesis, biological evaluation and docking analysis of substituted piperidines and (2-methoxyphenyl)piperazines [PDF]

Journal of the Serbian Chemical Society, 2016
A series of sixteen novel substituted piperidines and (2-methoxyphenyl)piperazines were synthesized, starting from the key intermediates 1-(2-methoxyphenyl)-4-(piperidin-4-yl)piperazine and 1-(2-methoxyphenyl)-4-(piperidin-4-ylmethyl)piperazine.
Penjišević Jelena Z., Šukalović Vladimir V., Andrić Deana B., Roglić Goran M., Novaković Irena T., Šoškić Vukić, Kostić-Rajačić Slađana V.   +6 more
doaj   +1 more source

Synthesis and Anticonvulsant Activity of Some Quinazolin-4-(3H)-one Derivatives

Molecules, 2008
A number of 3-substituted-2-(substituted-phenoxymethyl) quinazolin-4(3H)-one derivatives 4a,b, 5a-c, 6, 7a-f, 8a-e and 9a,b have been synthesized. Their structures have been elucidated on the basis of elemental analyses and spectroscopic studies (IR, 1H ...
Safinaz Abbas, Nagwa Abdel-Gawad, Hanan Georgey   +2 more
doaj   +1 more source

Advances in BODIPY Derivatives for Antibacterial Phototherapy

Angewandte Chemie, EarlyView.
This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv, Heejeong Kim, Hongchen Zhai, Hanqi Ren, Silu Wang, Cong Sun, Yafu Wang, Hosoowi Lee, Juyoung Yoon, Hua Zhang   +9 more
wiley   +2 more sources