Results 51 to 60 of about 39,960 (300)

Twelve 4-(4-methoxyphenyl)piperazin-1-ium salts containing organic anions: supramolecular assembly in one, two and three dimensions

Acta Crystallographica Section E: Crystallographic Communications, 2019
Twelve 4-(4-methoxyphenyl)piperazin-1-ium salts containing organic anions have been prepared and structurally characterized. The monohydrated benzoate, 4-fluorobenzoate, 4-chlorobenzoate and 4-bromobenzoate salts, C11H17N2O+·C7H5O2−·H2O (I), C11H17N2O ...
Haruvegowda Kiran Kumar, Hemmige S. Yathirajan, Sabine Foro, Christopher Glidewell   +3 more
doaj   +1 more source

Synthesis and Anticonvulsant Activity of Some Quinazolin-4-(3H)-one Derivatives

Molecules, 2008
A number of 3-substituted-2-(substituted-phenoxymethyl) quinazolin-4(3H)-one derivatives 4a,b, 5a-c, 6, 7a-f, 8a-e and 9a,b have been synthesized. Their structures have been elucidated on the basis of elemental analyses and spectroscopic studies (IR, 1H ...
Safinaz Abbas, Nagwa Abdel-Gawad, Hanan Georgey   +2 more
doaj   +1 more source

Synthesis, biological evaluation and docking analysis of substituted piperidines and (2-methoxyphenyl)piperazines [PDF]

Journal of the Serbian Chemical Society, 2016
A series of sixteen novel substituted piperidines and (2-methoxyphenyl)piperazines were synthesized, starting from the key intermediates 1-(2-methoxyphenyl)-4-(piperidin-4-yl)piperazine and 1-(2-methoxyphenyl)-4-(piperidin-4-ylmethyl)piperazine.
Penjišević Jelena Z., Šukalović Vladimir V., Andrić Deana B., Roglić Goran M., Novaković Irena T., Šoškić Vukić, Kostić-Rajačić Slađana V.   +6 more
doaj   +1 more source

A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury. [PDF]

, 2016
The p75 neurotrophin receptor is important in multiple physiological actions including neuronal survival and neurite outgrowth during development, and after central nervous system injury.
Alam, Antoine, Arnone, Michele, Baroni, Marco, Beattie, Michael S, Bono, Françoise, Bresnahan, Jacqueline C, Canolle, Benoit, Castel, Marie-Noelle, Delbary-Gossart, Sandrine, Delesque-Touchard, Nathalie, Ferguson, Adam R, Ferzaz, Badia, Herbert, Jean-Marc, Laboudie, Patricia, Lamarche, Isabelle, Lee, Sangmi, Lin, Amity, Manley, Geoffrey T, Sacramento, Jeffrey, Salegio, Ernesto A, Savi, Pierre   +20 more
core   +1 more source

A structural study of 2,4-dimethylaniline derivatives

Acta Crystallographica Section E: Crystallographic Communications, 2018
Crystallographic studies of nitrogen-containing small molecules aid in the elucidation of their structure–activity relationships and modes of aggregation.
Samuel C. Penner, Maryam Kalvandi, Jamie S. Ritch   +2 more
doaj   +1 more source

Synthetically modified bioisosteres of salicyl alcohol and their gastroulcerogenic assessment versus aspirin: biochemical and histological correlates [PDF]

, 2013
The present study was conducted to synthesize nitrogen containing derivatives of salicyl alcohol and to investigate in vivo their ulcerogenic potential in comparison with aspirin in rats.
Ali, Gowhar, Khan, Ikhtiar, Sewell, Robert David Edmund, Shahid, Muhammad, Subhan, Fazal, Ul Islam, Nazar, Ullah, Nasir   +6 more
core   +1 more source

Microfluidic Platform for Multiparametric Profiling of Fibrin Permeability, Fibrinolysis, and Cell Invasion

Advanced Functional Materials, EarlyView.
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal, Elizabeth M. Byrnes, Sanika Pandit, Halle J. Cantor, Muskan Aslam, Stacy Ban, Megan Palmisano, Rosemary Bayless, Ashley C. Brown, Michael Daniele   +9 more
wiley   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Biagio Palmisano, Silvia Franco, Roberta Angelini, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +14 more
wiley   +1 more source

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

Advanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij, Antonia G. Vasilopoulou, Lennard Spauwen, Antoinette van den Dikkenberg, Jasmijn V. Korpershoek, Mylene de Ruijter, Jos Malda, Bas G. P. van Ravensteijn, Tina Vermonden   +8 more
wiley   +1 more source

Synthesis of novel antibacterial and antifungal dithiocarbamate-containing piperazine derivatives via re-engineering multicomponent approach

Heliyon, 2022
A metal-free multicomponent synthetic route for the diverse preparation of dithiocarbamate-containing piperazine derivatives was developed through the C–N bond cleavage of DABCO ring.
Azim Ziyaei Halimehjani, Faezeh Dehghan, Vida Tafakori, Elaheh Amini, Seyyed Emad Hooshmand, Yazdanbkhsh Lotfi Nosood   +5 more
doaj   +1 more source