Development and Validation of a UPLC-MS/MS Method for Simultaneous Quantification of Ensartinib and Its Major Metabolite M465 in Rat Plasma and Application to Pharmacokinetic Studies. [PDF]
Jiang S +5 more
europepmc +1 more source
A 5-Azetidinyl BODIPY-Olaparib Conjugate for PARP-Targeted Nuclear and Orthotopic Oral Tumor Imaging. [PDF]
Yan K, Qi H, Dong X, Zhao W.
europepmc +1 more source
Prevalence of Benzodiazepine, Z-Drug and Melatonin Use in Australian Residential Aged Care Facilities: A Systematic Review and Meta-Analysis. [PDF]
Liu YJ +6 more
europepmc +1 more source
Malignant reninoma with pulmonary metastasis and ATRX mutation treated with olaparib: a case report of specialized treatment. [PDF]
Zi GR, Zhang DJ, He DL, Feng RL, Ke CX.
europepmc +1 more source
Iridium-Catalyzed Regio- and Diastereoselective Synthesis of C-Substituted Piperazines [PDF]
Piperazine rings are essential motifs frequently found in commercial drugs. However, synthetic methodologies are mainly limited to N-substituted piperazines, preventing structural diversity.
Miguel Ciriano +2 more
exaly +2 more sources
Biocatalytic Access to Piperazines from Diamines and Dicarbonyls
Given the widespread importance of piperazines as building blocks for the production of pharmaceuticals, an efficient and selective synthesis is highly desirable.
Bettina Nestl
exaly +2 more sources
Direct synthesis of piperazines containing dithiocarbamate derivatives via DABCO bond cleavage
DABCO bond cleavage with dithiocarbamic acid salts was applied as a direct synthetic route for the preparation of a novel category of piperazines containing dithiocarbamate functional group.
Seyyed Emad Hooshmand +1 more
exaly +1 more source
Synthesis and antitubercular activity of 1,2,4-trisubstitued piperazines
Parallel solid phase synthesis offers a unique opportunity for the synthesis and screening of large numbers of compounds and significantly enhances the prospect of finding new leads.
Kyle Rohde, Adel Nefzi
exaly +2 more sources
Related searches:
Derivatives of Piperazine. XXI. Synthesis of Piperazine and C-Substituted Piperazines
Journal of the American Chemical Society, 1947L J, KITCHEN, C B, POLLARD
openaire +2 more sources

