Results 131 to 140 of about 14,956 (188)

Iridium-Catalyzed Regio- and Diastereoselective Synthesis of C-Substituted Piperazines [PDF]

open access: yesACS Catalysis, 2023
Piperazine rings are essential motifs frequently found in commercial drugs. However, synthetic methodologies are mainly limited to N-substituted piperazines, preventing structural diversity.
Miguel Ciriano   +2 more
exaly   +2 more sources

Biocatalytic Access to Piperazines from Diamines and Dicarbonyls

open access: yesACS Catalysis, 2018
Given the widespread importance of piperazines as building blocks for the production of pharmaceuticals, an efficient and selective synthesis is highly desirable.
Bettina Nestl
exaly   +2 more sources

Direct synthesis of piperazines containing dithiocarbamate derivatives via DABCO bond cleavage

open access: yesTetrahedron Letters, 2020
DABCO bond cleavage with dithiocarbamic acid salts was applied as a direct synthetic route for the preparation of a novel category of piperazines containing dithiocarbamate functional group.
Seyyed Emad Hooshmand   +1 more
exaly   +1 more source

Synthesis and antitubercular activity of 1,2,4-trisubstitued piperazines

open access: yesBioorganic and Medicinal Chemistry Letters, 2016
Parallel solid phase synthesis offers a unique opportunity for the synthesis and screening of large numbers of compounds and significantly enhances the prospect of finding new leads.
Kyle Rohde, Adel Nefzi
exaly   +2 more sources

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