In this work, a catalytic enantioselective imidation approach is presented for the preparation of enantioenriched sulfinamidines from sulfenamides, employing a chiral dirhodium(II) tetracarboxylate catalyst. This method enables the imidation of N,N‐bisalkyl sulfenamides in yields of up to 98% and enantiomeric ratios up to 98:2, with a catalyst loading ...
Michael Andresini +7 more
wiley +1 more source
The toxicology and characteristics of fatal new psychoactive stimulant and hallucinogen-related poisonings in Australia, 2000-2025. [PDF]
Darke S +4 more
europepmc +1 more source
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han +5 more
wiley +1 more source
Discovery of unprecedented prenylated indole piperazines and pyrazines through cryptic biosynthetic gene cluster heterologous expression. [PDF]
Zha Z +12 more
europepmc +1 more source
Potential value of triple drug therapy with ivermectin, diethylcarbamazine, and albendazole (IDA) to accelerate elimination of lymphatic filariasis and onchocerciasis in Africa [PDF]
Fischer, Peter U +3 more
core +3 more sources
Parametric uncertainty in the PZ/AFS post‐combustion carbon‐capture process model compromises the reliability of process designs extracted via traditional, deterministic optimization methods. We identify the twelve parameters exhibiting highest impact on capture and costs, and mitigate the design risk stemming from those via formulating and solving a ...
Ilayda Akkor +4 more
wiley +1 more source
Bioactivity Profiles of Progressively Ring-Fluorinated Cyclohexyl Motifs in the WKYMVm Peptide as Formylpeptide FPR2 Agonists and in Keto-Piperazines as Antitrypanosome Agents. [PDF]
He M +6 more
europepmc +1 more source
Lignin‐Derived Flame Retardants for Enhanced Fire Safety: A Review
Lignin is a promising halogen‐free and bio‐based flame‐retardant component, where structure, plant origin, and extraction route govern its fire performance. While unmodified lignin promotes char formation, phosphorylation and P‐N/P‐Si functionalization can enhance its fire performance. Lignin‐based intumescent systems and nanostructures can reduce heat
Elif Kaynak +4 more
wiley +1 more source
Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry. [PDF]
Ten A +5 more
europepmc +1 more source

