Results 151 to 160 of about 43,723 (349)

18F‐Radiopharmaceutical Diversification Enabled by Deaminative Cross‐Electrophile Couplings

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
A general Ni‐mediated (C)sp2–(C)sp3 cross‐coupling expedites access to 18F‐radiopharmaceuticals, essential for positron emission tomography imaging and drug discovery. This late‐stage diversification approach was implemented across three user‐friendly automated protocols affording 18F‐radiotracers in sufficient quantities for imaging.
Isabella F. Ogilvy, Joseph Ford, Sebastiano Ortalli, Evelien Renders, Thomas R. Hayes, Shuanglong Liu, Inne Mortiers, Anastasia Nikolopoulou, Alexandre M. Sorlin, Andrés A. Trabanco, Matthew Tredwell, Peter J. J. A. Buijnsters, Rhys Salter, Véronique Gouverneur   +13 more
wiley   +2 more sources

Synthesis, alpha-adrenoceptors affinity and alpha 1-adrenoceptor antagonistic properties of some 1,4-substituted piperazine derivatives.

, 2011
Henryk Marona, Monika Kubacka, Barbara Filipek, Agata Siwek, Małgorzata Dybała, Edward Szneler, T. Pociecha, Agnieszka Gunia‐Krzyżak, Anna M. Waszkielewicz   +8 more
openalex   +2 more sources

Piperazine and Male Fern in Expulsion of Tapeworms [PDF]

, 1958
L Goodwin, O. D. Standen
openalex   +1 more source

Probing skin photoallergens in reconstructed human epidermis: An EPR spin trapping investigation

Photochemistry and Photobiology, Volume 101, Issue 2, Page 275-281, March/April 2025.
We present an original proof‐of‐concept methodology to probe radical generation from allergens in contact with photoexposed skin, using electron paramagnetic resonance and spin trapping in a reconstructed human epidermis model mimicking real‐life exposure scenarios.
Yannick Port‐Lougarre, Guillaume Voegeli, Bertrand Vileno, Elena Giménez‐Arnau   +3 more
wiley   +1 more source

Asymmetric synthesis and biological evaluation of N-cyclohexyl-4-[1-(2,4-dichlorophenyl)-1-(p-tolyl)methyl]piperazine-1-carboxamide as hCB1 receptor antagonists

, 2011
Linghuan Gao, Min Li, Tao Meng, Hongli Peng, Xin Xie, Yongliang Zhang, Jin Yu, Xin Wang, Libo Zou, Jingkang Shen   +9 more
openalex   +1 more source

Pyrene‐Conjugated, 2‐Pyridinecarboxaldehyde Derivatives as N‐Terminus‐Specific Tags for MALDI‐ and LALDI‐MS

Rapid Communications in Mass Spectrometry, Volume 40, Issue 8, 30 April 2026.
ABSTRACT Background Proteolytic processing is a fundamental post‐translational modification. Liquid chromatography–tandem mass spectrometry (LC–MS/MS) workflows are powerful for degradomic analyses but inherently sacrifice spatial information, a critical aspect for investigating biological systems such as aberrant extracellular matrix remodeling and ...
Mujia Jenny Li, Murat Kucukdisli, Florian Braun, David W. Will, Nadine Meier, Bettina Wehrle, Larissa Chiara Meyer, Melanie Christine Föll, Oliver Schilling   +8 more
wiley   +1 more source

Experimental Chemotherapy of Schistosomiasis. II. Laboratory and Clinical Trials with A-16612, a Piperazine Derivative

, 1967
Naftale Katz, J. Pellegrino, Cleida A. Oliveira, Aluisio S. Cunha   +3 more
openalex   +1 more source

Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin, Chen Qian, Wenhao Li, Qihan Wang, Qifeng Sheng, Zheqing Chen, Wei Zhang, Wenming Li, Gaoran Ge, Zhanjun Yan, Dechun Geng   +10 more
wiley   +1 more source

Synthesis of Piperazines. XIV

, 1960
Takeo Ishiguro, Masaki Matsumura, Hiromu Murai   +2 more
openalex   +2 more sources

Usability of Amorphous Manganese Oxide for Assessing the Proteoglycan Content in Articular Cartilage

Magnetic Resonance in Chemistry, Volume 64, Issue 2, Page 207-216, February 2026.
Amorphous manganese oxide nanoparticles exhibit high relaxivity and diffuse into articular cartilage faster than Gd‐DTPA, making them a promising agent for evaluating proteoglycan content. ABSTRACT Osteoarthritis (OA) is a highly common chronic disease that decreases functional capacity and can cause disability. The early detection of the disease could
Riikka M. Korpi, Susanna Ahola, Gamzegul Behrouz, Eveliina Lammentausta, Sakari S. Karhula, Simo Saarakkala, Lassi Rieppo, Mikko Finnilä, Siegfried Stapf, Jessica Rosenholm, Roberto Blanco Sequieros, Miika T. Nieminen, Ville‐Veikko Telkki   +12 more
wiley   +1 more source