Results 11 to 20 of about 20,000 (189)

New psychoactive substances and the risks of consumption in children and adolescents [PDF]

open access: yesRomanian Journal of Pediatrics, 2019
According to the definition established by the European Monitoring Center for Drugs and Drug Addiction (EMCDDA) a “new psychoactive substance is considered any narcotic or psychotropic substance in pure form or in preparations, which is not controlled by
Viorela Nitescu
doaj   +1 more source

THE PREPARATION OF PIPERAZINE. [PDF]

open access: yesJournal of the American Chemical Society, 1918
n ...
Pratt, David S., Young, Charles O.
openaire   +2 more sources

Fifteen 4-(2-methoxyphenyl)piperazin-1-ium salts containing organic anions: supramolecular assembly in zero, one, two and three dimensions

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2020
Fifteen 4-(2-methoxyphenyl)piperazin-1-ium salts containing organic anions have been prepared and structurally characterized. In the isostructural 4-chlorobenzoate and 4-bromobenzoate salts, C11H17N2O+·C7H4ClO2− (I) and C11H17N2O+·C7H4BrO2− (II), and the
Chayanna Harish Chinthal   +5 more
doaj   +1 more source

Development of Piperazine- and Oxazine-Linked Pyrimidines as p65 Subunit Binders of NF–κB in Human Breast Cancer Cells

open access: yesBiomedicines, 2023
Nuclear factor kappa B (NF–κB) is a potential therapeutic target in breast cancer. In the current study, a new class of oxazine– and piperazine–linked pyrimidines was developed as inhibitors of NF–κB, overcoming the complexity of the oxazine structure ...
Akshay Ravish   +10 more
doaj   +1 more source

Crystal structures of the recreational drug N-(4-methoxyphenyl)piperazine (MeOPP) and three of its salts

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2020
Crystal structures are reported for N-(4-methoxyphenyl)piperazine (MeOPP), (I), and for its 3,5-dinitrobenzoate, 2,4,6-trinitrophenolate (picrate) and 4-aminobenzoate salts, (II)–(IV), the last of which crystallizes as a monohydrate. In MeOPP, C11H16N2O,
Haruvegowda Kiran Kumar   +4 more
doaj   +1 more source

Hydrogen-Bonded Chain of Rings Motif in N-(4-Methoxyphenyl)piperazin-1-ium Salts with Benzoate Anions: Supramolecular Assemblies and Their Energy Frameworks

open access: yesCrystals, 2022
The crystal structures of three salts, namely N-(4-methoxyphenyl)piperazin-1-ium ethoxybenzoate monohydrate (I), N-(4-methoxyphenyl)piperazin-1-ium methoxybenzoate monohydrate (II) and N-(4-methoxyphenyl)piperazin-1-ium hydroxybenzoate monohydrate (III),
Prabhakar Priyanka   +8 more
doaj   +1 more source

Chlorocobalt complexes with pyridylethyl-derived diazacycloalkanes

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2022
Syntheses are described for the blue/purple complexes of cobalt(II) chloride with the tetradentate ligands 1,4-bis[2-(pyridin-2-yl)ethyl]piperazine (Ppz), 1,4-bis[2-(pyridin-2-yl)ethyl]homopiperazine (Phpz), trans-2,5-dimethyl-1,4-bis[2-(pyridin-2-yl ...
Anthony W. Addison   +7 more
doaj   +1 more source

Synthesis and Molecular Structure of tert-Butyl 4-(2-tert-butoxy-2-oxoethyl)piperazine-1-carboxylate

open access: yesCrystals, 2012
The crystal and molecular structure of tert-butyl 4-(2-tert-butoxy-2-oxoethyl)-piperazine-1-carboxylate is reported. The title compound crystallizes from a petroleum ether/ethyl acetate mixture in the monoclinic space group P 21/c with four molecules in ...
Martin Köckerling   +2 more
doaj   +1 more source

A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines

open access: yesMolecules, 2022
We report a short synthetic route for synthesizing 2,3-substituted piperazine acetic acid esters. Optically pure amino acids were efficiently converted into 1,2-diamines that could be utilized to deliver the title 2,3-substituted piperazines in five ...
Srinivas Chamakuri   +6 more
doaj   +1 more source

Alkylated Piperazines and Piperazine-Azole Hybrids as Antifungal Agents [PDF]

open access: yesJournal of Medicinal Chemistry, 2017
The extensive use of fluconazole (FLC) and other azole drugs has caused the emergence and rise of azole-resistant fungi. The fungistatic nature of FLC in combination with toxicity concerns have resulted in an increased demand for new azole antifungal agents.
Nishad Thamban Chandrika   +5 more
openaire   +2 more sources

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