Results 231 to 240 of about 43,723 (349)

Functionalizing Nucleic Acids: Synthesis and Purification Strategies for Bioconjugates as Biomaterials

open access: yesSmall, Volume 22, Issue 5, 22 January 2026.
Nucleic acid‐ligand conjugates combine the distinct properties of macromolecular ligands with the versatility of DNA/RNA nanotechnology. In biomaterial and nanomedicine applications, highly purified products are paramount, requiring reliable synthesis and purification methods.
Nico Alleva   +4 more
wiley   +1 more source

General Procedures for the Lithiation/Trapping of N-Boc Piperazines.

open access: yesJournal of Organic Chemistry, 2017
James D. Firth, P. O’Brien, L. Ferris
semanticscholar   +1 more source

DNA‐Loaded Nanoparticles Reprogram the Tumor Immune Microenvironment to Treat Brain Tumors

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Biodegradable poly(beta‐amino ester) nanoparticles can be employed to deliver immunostimulatory genes (4‐1BBL and IL‐12) to reprogram brain tumor cells into antigen‐presenting cells to stimulate an anti‐tumor response, resulting in tumor regression and long‐term survival in GBM and meningioma models.
Joanna Yang   +14 more
wiley   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

open access: yesSmall Methods, Volume 10, Issue 2, 22 January 2026.
The review presents a comprehensive overview of each component of lipid nanoparticles(LNPs)and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu   +6 more
wiley   +1 more source

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