Results 91 to 100 of about 76,241 (267)

Diquaternary Ammonium Compounds in Zeolite Synthesis: Cyclic and Polycyclic N-Heterocycles Connected by Methylene Chains [PDF]

, 2009
An additional dimension has been added to our long-standing studies in high silica zeolite synthesis via a guest/host synergism. We have created and studied the impact of making symmetric diquaternary ammonium compounds, by varying the chain length ...
Burton, Allen W., Hwang, Son-Jong, Jackowski, Anna, Zones, Stacey I.   +3 more
core   +1 more source

Crystal structure of 4-chloro-N-[2-(piperidin-1-yl)ethyl]benzamide monohydrate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C14H19ClN2O2·H2O, the piperdine ring adopts a chair conformation. The dihedral angle between the mean plane of the piperidine ring and that of the phenyl ring is 41.64 (1)°.
K. Prathebha, D. Reuben Jonathan, B. K Revathi, S. Sathya, G. Usha   +4 more
doaj   +1 more source

Nanomolar-potency 'co-potentiator' therapy for cystic fibrosis caused by a defined subset of minimal function CFTR mutants. [PDF]

, 2019
Available CFTR modulators provide no therapeutic benefit for cystic fibrosis (CF) caused by many loss-of-function mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel, including N1303K. We previously introduced the
Finkbeiner, Walter E, Haggie, Peter M, Nielson, Dennis W, Phuan, Puay-Wah, Rivera, Amber A, Tan, Joseph-Anthony, Verkman, Alan S, Zlock, Lorna   +7 more
core  

Catalytic asymmetric synthesis of the alkaloid (+)-myrtine [PDF]

, 2008
A new protocol for the asymmetric synthesis of trans-2,6-disubstituted-4-piperidones has been developed using a catalytic enantioselective conjugate addition reaction in combination with a diastereoselective lithiation–substitution sequence; an efficient
Adriaan J. Minnaard, Albrow, Alexakis, Alexakis, Anderson, Bach, Back, Beak, Beak, Beak, Beak, Beak, Beak, Beak, Ben L. Feringa, Bennett, Bennett, Berkheij, Bertini Gross, Brooks, Comins, Comins, Comins, Comins, Comins, Comins, Comins, Curtin, d'Augustin, Davis, Dieter, Dieter, Dieter, Dieter, Dieter, Eilitz, Frankel, Fraser, Gallagher, Garcia-Ruiz, Gardette, Gelas-Mialhe, Hoffmann, Houk, Kerrick, King, Leclercq, Liang, Maria Gabriella Pizzuti, Pilli, Pilli, Pineschi, Pàmies, Remuson, Slosse, Slosse, Still, Tawara, Vuagnoux-d'Augustin, Vuagnoux-d'Augustin, Watson, Whisler, Šebesta   +62 more
core   +1 more source

Controlled Delivery and Light‐Induced Release of Magic Spot Nucleotides in Escherichia coli

Angewandte Chemie International Edition, EarlyView.
We synthesized photocaged, clickable and isotope‐labeled “magic spot” Nucleotides and delivered them into Escherichia coli comparing different approaches. Light‐controlled release inside living cells enabled tracking of their conversion from pppGpp to ppGpp by capillary electrophoresis mass spectrometry and revealed their impact on the growth rate of a
Christoph Popp, Patrick Moser, Anselm Schwoerbel, Xinwei Liu, Johannes Freitag, Pinku Sarmah, Isabel Prucker, Robert Zscherp, Xuan Wang, Philipp Klahn, Hans‐Georg Koch, Gert Bange, Henning J. Jessen   +12 more
wiley   +1 more source

Crystal structure of the 1:2 adduct of bis(piperidinium) sulfate and 1,3-dimethylthiourea

Acta Crystallographica Section E: Crystallographic Communications, 2017
In the title compound, 2C5H12N+·SO42−·2C3H8N2S, the C=S groups of the two independent 1,3-dimethylurea molecules and the sulfur atom of the anion lie on twofold axes. The packing is centred on bis(piperidinium) sulfate ribbons parallel to the c axis; the
Cindy Döring, Julian F. D. Lueck, Peter G. Jones   +2 more
doaj   +1 more source

Untersuchungen zur trägerarmen Radiofluorierung nicht-aktivierter Aromaten mit n.c.a. [18F]Fluorid [PDF]

, 2011
In vivo imaging with positron emission tomography generally demands radiotracers with a high specific activity. In case of fluorine-18 the required no-carrier-added (n.c.a.) starting material is only available in form of fluoride. This and the short half-
Cardinale, Jens
core  

A practical synthesis of the 13C/15N-labelled tripeptide N-formyl-Met-Leu-Phe, useful as a reference in solid-state NMR spectroscopy [PDF]

, 2008
A mild synthetic method for N-formyl-Met-Leu-Phe-OH (1) is described. After Fmoc solid phase peptide synthesis, on-bead formylation and HPLC purification, more than 30 mg of the fully 13C/15N-labelled tripeptide 1 could be isolated in a typical batch ...
Breitung, Sven Thomas, Lopez, Jakob J., Dürner, Gerd, Glaubitz, Clemens, Göbel, Michael, Suhartono, Marcel   +5 more
core   +1 more source

Enantioselective Synthesis of Sulfinamidines via Asymmetric Rhodium–Catalyzed Imidation of Sulfenamides

ChemistryEurope, EarlyView.
In this work, a catalytic enantioselective imidation approach is presented for the preparation of enantioenriched sulfinamidines from sulfenamides, employing a chiral dirhodium(II) tetracarboxylate catalyst. This method enables the imidation of N,N‐bisalkyl sulfenamides in yields of up to 98% and enantiomeric ratios up to 98:2, with a catalyst loading ...
Michael Andresini, Théo Bissonnier, Juline Courtois, Pascal Retailleau, Benjamin Darses, Jean‐François Poisson, Tanguy Saget, Philippe Dauban   +7 more
wiley   +1 more source

Fibrillisation of hydrophobically modified amyloid peptide fragments in an organic solvent [PDF]

, 2007
The self-assembly of a hydrophobically modified fragment of the amyloid beta(A beta) peptide has been studied in methanol. The peptide FFKLVFF is based on A beta(16-20) extended at the N terminus by two phenylalanine residues.
Castelletto, Valeria, Hamley, Ian W., Krysmann, M.J.   +2 more
core   +1 more source