Results 121 to 130 of about 37,707 (289)
Background Podocytes are integral to the maintenance of the glomerular filtration barrier. Their injury results in proteinuria and disease progression in lupus nephritis (LN). Aberrant IgG glycosylation drives podocyte injury in LN and leads to cytoskeletal rearrangement, motility changes and decreased nephrin production.
Rhea Bhargava+9 more
wiley +1 more source
Advances in Metal‐Free Transamidation: A Sustainable Approach to Amide Bond Formation
This review highlights the recent developments of transamidation reactions under metal‐free reaction conditions. Various amines including weak nucleophilic amines such as aromatic amines have been used to achieve the transamidation reactions under mild and relatively green reaction conditions. Abstract The amide functionalities are a crucial functional
Niharan Sivaraj+2 more
wiley +1 more source
Photoswitchable cross‐linkers have the ability to connect two residues on a biomolecule, thereby causing large changes in the structure and function of the target upon irradiation. The design, synthesis and purification of cross‐linkers with large end‐to‐end distances remains challenging, especially for applications in chemical biology.
Jana Volarić+3 more
wiley +1 more source
Trifluoroacetyl‐substituted D–π–A fluorophore, featuring relatively extended and planar conjugated structure with piperidyl donor and trifluoroacetyl acceptor, demonstrated strong solvatochromism and giga Stokes shifts. This unique and strong acceptor has possibilities to achieve the design of fluorophore for various application, represented by ...
Alto Hori, Gen‐ichi Konishi
wiley +1 more source
Integrating Affinity Chromatography in the Platform Process for Adenovirus Purification
Peptide‐functionalized affinity resins with high adenovirus binding capacity, recovery, and contaminant removal afford excellent productivity, and reduced impurities in a three‐step purification process. ABSTRACT Adenoviral vectors (AdVs) are gaining prominence in cancer therapy and vaccine development, posing the need for a modern AdV manufacturing ...
Yuxuan Wu+7 more
wiley +1 more source
Piperidine Complexes of Thiocyanates of Zinc, Cadmium, Cobalt and Nickel [PDF]
S. Sahay, P. C. Sinha
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Review on the o‐Aminoaniline Moiety in Peptide and Protein Chemistry
The ability to prepare functional peptides and protein molecules is essential to understand fundamental biological processes and develop novel therapeutics for numerous diseases. In this review, Hong et al. document the development of o‐aminoaniline derivatives for chemical protein synthesis, peptide C‐terminus diversification, and cyclic peptide ...
Ziyong Z. Hong
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Inhibition of Sterol Biosynthesis by 2-Isopropyl-4-dimethylamino-5-methylphenyl-1-piperidine Carboxylate Methyl Chloride in Tobacco and Rat Liver Preparations [PDF]
Trevor J. Douglas, L. G. Paleg
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