Results 131 to 140 of about 84,342 (322)

Comparison of In Silico AChE Inhibitory Potentials of Some Donepezil Analogues

Pharmata
Cholinesterases are important in ensuring hemostasis in our body. Excessive increase in cholinesterase function causes various cholinergic dysfunctions. Alzheimer's is a disease characterized by loss of cholinergic activity, which is especially common in
Mehmet Koca
doaj  

SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2020
This study is aimed at evaluating the impact of N- and S- bonding modes of thiocyanate substituent on catecholase activity as its presence in the coordination sphere of the metal complex can either reduce catecholase activity or otherwise. 4-Methyl-2-(
AYOWOLE O. AYENI, GARETH M. WATKINS 1
doaj  

The chromatographic identification of some biologically important phosphate esters [PDF]

, 1951
the objective of the present work was to provide a means for separating and indentifying phosphate esters involved in glycolysis in higher plants. Paper chromatography of phosphate esters has been employed by several workers, most notably Benson et al ...
Axelrod, Bernard, Bandurski, Robert S.
core  

Design and Synthesis of Aryl-Piperidine Derivatives as Potent and Selective PET Tracers for Cholesterol 24-Hydroxylase (CH24H)

, 2022
Shuhei Ikeda, Y. Kajita, Maki Miyamoto, Kouta Matsumiya, Tsuyoshi Ishii, Toshiya Nishi, Sean C. Gay, Weston Lane, Cristian Constantinescu, David Alagille, Caroline Papin, Gilles Tamagnan, Takanobu Kuroita, Tatsuki Koike   +13 more
openalex   +1 more source

Electrochemical Three‐Component Synthesis of Vinyl Sulfonamides via Decarboxylative Sulfonylation of Cinnamic Acids

ChemSusChem, EarlyView.
An efficient, metal‐free electrochemical three‐component reaction of cinnamic acids, SO2, and amines to access (E)‐β‐styryl sulfonamides is reported. Utilizing graphite electrodes and SO2 stock solutions, this decarboxylative protocol proceeds under mild conditions with high regio‐ and stereoselectivity.
Po‐Chung Chien, Harald Kelm, Georg Manolikakes   +2 more
wiley   +1 more source

Crystallization of the B-800-850-complex from Rhodopseudomonas acidophila strain 7750 [PDF]

, 1985
Cogdell, Richard J., Dobler, J., Lindsay, J. G., Mackenzie, R. C., Michel, H., Michel-Beyerle, M.E., Woolley, K., Zinth, Wolfgang   +7 more
core   +1 more source

Alginate Oligosaccharides Attenuate Ochratoxin A‐Induced Liver Injury through Regulating the Interaction of Nrf2 and NF‐κB Signaling Pathways

Food Frontiers, EarlyView.
A schematic illustration for the protective effects of AOS on OTA‐induced liver injury in mice. AOS, alginate oligosaccharides; CAT, catalase; GSTT1, glutathione S‐transferase theta 1; HO‐1, heme oxygenase 1; IκBα, inhibitor kappa B alpha; IL‐1β, interleukin‐1β; IL‐6, interleukin‐6; Keap1, kelch‐like ech‐associated protein 1; NF‐κB, nuclear factor ...
Yue Zhao, Xueqing Ye, Yan Guo, Zhongxiang Zhao, Qinghua Yao, Yaoyao Wang, Huimei Liu, Ziwei Lin, Wenchao Liu   +8 more
wiley   +1 more source

Identification of Novel Piperidine and Pyrrolidine Derivatives as Potent Inhibitors of Pancreatic Lipase-Based Molecular Docking and In Vitro Testing

Scientia Pharmaceutica
Obesity is a major global health concern associated with increased risks of chronic diseases and mortality. Inhibiting pancreatic lipase, a key enzyme in dietary fat absorption, presents a promising therapeutic approach.
Acharaporn Duangjai, Kwanruthai Tadpetch, Vatcharin Rukachaisirikul, Chutima S. Vaddhanaphuti, Maleeruk Utsintong   +4 more
doaj   +1 more source

Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors

, 2011
Cristina Rossi, Marina Porcelloni, Piero D’Andrea, Christopher I. Fincham, Alessandro Ettorre, Sandro Mauro, Antonella Squarcia, Mario Bigioni, Massimo Parlani, Federica Nardelli, Monica Binaschi, Carlo Alberto Maggi, Daniela Fattori   +12 more
openalex   +1 more source

Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects

Future Postharvest and Food, EarlyView.
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq, Sajad Ahmad Mir, Zahida Naseem   +2 more
wiley   +1 more source