Results 151 to 160 of about 38,750 (255)

Redox‐Active Guanidines

ChemElectroChem, Volume 13, Issue 12, 17 June 2026.
Redox‐active guanidines, comprising guanidino‐functionalized aromatics (GFAs) and redox‐active urea azines (RAAs), are electron donors and strong Lewis and Brønsted bases that are used in several applications. They act as redox‐active ligands in bistable coordination compounds and as reagents in dehydrogenative coupling reactions and proton‐coupled ...
Hans‐Jörg Himmel
wiley   +1 more source

Exploring insecticidal activity and SAR study of newly synthesized Benzo[h]quinoline-based heterocycles against Aphis craccivora Koch. and Culex pipiens L. Larvae. [PDF]

Sci Rep
El-Helw EAE, Abdel-Haleem DR, Khalil AK, Ramadan SK.   +3 more
europepmc   +1 more source

Geminale Difunktionalisierung von Ketonen durch C–S Bindungs‐insertion photogenerierter Donor–Donor Diazoverbindungen

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Die geminale Difunktionalisierung leicht verfügbarer Bausteine ermöglicht einen schnellen Zugang zu molekularer Komplexität. Diese Arbeit stellt eine Strategie vor, um zwei unterschiedliche funktionelle Gruppen an einem Carbonylkohlenstoff zu installieren, indem dieser in eine Donor–Donor‐Diazo‐Verbindung überführt wird. Die Methode ist sowohl im Batch‐
Vincent George, Aryaman Pattanaik, Daniel Maddox, Lukas M. Sigmund, Giovanna Mejia, Sara Pahlén, Simon O. Angerer, Maria Schmoll, Lisa Marie Schneider, Nidhal Selmi, Mikhail Kabeshov, Giulia Bergonzini, Julia Rehbein, Burkhard König   +13 more
wiley   +1 more source

Potent, Selective Pyrrolopyrimidine PDE11A4 Inhibitors with Improved Pharmaceutical Properties. [PDF]

ACS Med Chem Lett
Mahmood SU, Boddu RK, Eberhard J, Hoffman CS, Gordon J, Colussi D, Childers W, Amurrio E, Danaher M, Kelly MP, Rotella DP.   +10 more
europepmc   +1 more source

Polyethylene Microplastics Inhibit Peanut Nodulation via Metabolic and Transcriptional Pathways. [PDF]

Plants (Basel)
Wu Y, Wu Z, Zheng Y, Yang J, Zhang J, Wang H, Yu T, Wu J, Li S.   +8 more
europepmc   +1 more source

Geminal Difunctionalization of Ketones via C─S Bond Insertion of Photogenerated Donor–Donor Diazo Compounds

Angewandte Chemie International Edition, Volume 65, Issue 25, 15 June 2026.
Geminal difunctionalization of readily available building blocks provides rapid access to molecular complexity. This work introduces a strategy for installing two distinct functional groups on a carbonyl carbon by transforming it into a donor–donor diazo compound, enabling both batch and flow applications with broad solvent compatibility.
Vincent George, Aryaman Pattanaik, Daniel Maddox, Lukas M. Sigmund, Giovanna Mejia, Sara Pahlén, Simon O. Angerer, Maria Schmoll, Lisa Marie Schneider, Nidhal Selmi, Mikhail Kabeshov, Giulia Bergonzini, Julia Rehbein, Burkhard König   +13 more
wiley   +1 more source

Discovery and Characterization of a Nonacidic Small-Molecule Inhibitor of the Sodium-Coupled Dicarboxylate Transporter NaCT. [PDF]

J Med Chem
Quigley A, Kley JT, Pautsch A, Kauschke SG, Chu-Antypas A, Tessitore A, Strain-Damerell C, Shrestha L, Wiedenmayer D, Burgess-Brown NA, Fedorov O, Carpenter EP.   +11 more
europepmc   +1 more source

Enantioselective Total Synthesis of Two Aromatized Halicyclamines. [PDF]

J Am Chem Soc
Firestone ZD, Grigolo TA, Pernichelle FG, Smith JM.   +3 more
europepmc   +1 more source

Mapping the Substrate Specificity Landscape of PAD2 and PAD4 Enzymes

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Protein citrullination, driven by peptidyl arginine deiminases (PAD2, PAD4), is linked to multiple diseases. Using a combinatorial peptide library and advanced mass spectrometry, we reveal distinct substrate selectivity profiles of PAD2 and PAD4. While PAD2 broadly citrullinates arginine‐containing peptides, PAD4 is highly sequence‐restricted, with ...
Adina Borbély, Arnold Steckel, Dávid Papp, Domonkos Pál, Katalin Uray, Viktória Goldschmidt Gőz, Gitta Schlosser   +6 more
wiley   +1 more source

Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley   +1 more source