Results 141 to 150 of about 76,241 (267)
Stereo-Control in Zn(II) and Cd(II) Complexes of Tetraamines with Azacyclic Cores
Halide-dictated stereoselective formation of octahedral Δ-cis-α-[Zn(L)Cl2] or trigonal bipyramidal Λ-[Zn(L)I]I, where L is a chiral tetramine with a pyrrolidine or piperidine core, has been observed in both the solid state and in solution through a ...
Hanan A. A. Althobaiti +5 more
doaj +1 more source
Photothermal Conversion Promotes Challenging S<sub>N</sub>Ar for Facile C─N Bond Formation. [PDF]
Photothermal conversion enables facile aromatic C─N bond formation via red light irradiation. A variety of inter‐ and intramolecular SNAr transformations are achieved under mild, schematically simple conditions. Additionally, a thermally promoted halogen exchange mechanism provides access to aryl bromides, chlorides, and fluorides – making this ...
Matter ME, Devin RC, Stache EE.
europepmc +2 more sources
The chromatographic identification of some biologically important phosphate esters [PDF]
the objective of the present work was to provide a means for separating and indentifying phosphate esters involved in glycolysis in higher plants. Paper chromatography of phosphate esters has been employed by several workers, most notably Benson et al ...
Axelrod, Bernard, Bandurski, Robert S.
core
Residues with backbone N‐amination have been introduced into a region of parallel β‐sheet secondary structure. Contrary to predictions, the N‐amination of Trp9 or Phe33 did not give an increase in the thermal stability of DS119. MD simulations suggest this is due to the highly fluctuating nature of the β‐sheet region. ABSTRACT The miniprotein DS119 has
Yushi Qiao +4 more
wiley +1 more source
(1R,2R,6S)-3-Methyl-6-(3-(4-phenylpiperidin-1-yl)prop-1-en-2-yl)cyclohex-3-ene-1,2-diol
Parkinson’s disease (PD) is a progressive neurodegenerative disorder whose primary manifestation is motor dysfunction. Previous research showed that (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol (Prottremine) exhibits potent ...
Alexandra V. Podturkina +4 more
doaj +1 more source
Influence of Peptide‐Based Chelator Sequences on HER2‐Targeting Radiopeptide
Peptide‐based chelator consisting of Cys‐Gly‐Gly‐Gly incorporated into HER2‐targeting rL‐A9 peptide for 99mTc‐labeling. [99mTc]Tc‐CGGG‐rL‐A9 exhibited high binding affinity and tumor uptake and retention. ABSTRACT In our pursuit of developing HER2‐targeting radiolabeled peptides for detection and therapy of HER2‐positive breast cancer, the previously ...
Sonal Gupta +5 more
wiley +1 more source
Abstract Background and aims While the health hazards of synthetic cannabinoid receptor agonists (SCRAs) are often approximated using in vitro pharmacological parameters as surrogate, this approach fails to consider pharmacokinetic and pharmacodynamic complexity.
Michaela J. Sommer +3 more
wiley +1 more source
Carboranylmethylene-substituted phosphazenes and polymers thereof [PDF]
Carboranylmethylene-substituted cyclophosphazenes are described which can be thermally polymerized into carboranylmethylene-substituted phosphazene polymers. The polymers are useful as thermally stable coatings.
Allcock, H. R., Scopelianos, A. G.
core +1 more source
Soluble Epoxide Hydrolase Inhibitors Improve Cornea Alkali Wound Healing
Soluble epoxide hydrolase (sEH) inhibition enhances corneal wound healing following alkali injury. (A) Schematic representation of corneal injury induced by NaOH or ammonia showing elevated sEH expression in corneal keratocytes. This leads to rapid hydrolysis of epoxy fatty acids (EpFAs), reducing their bioavailability and contributing to enhanced ...
Xiaowen Lu +10 more
wiley +1 more source

