Results 141 to 150 of about 84,342 (322)
(1R,2R,6S)-3-Methyl-6-(3-(4-phenylpiperidin-1-yl)prop-1-en-2-yl)cyclohex-3-ene-1,2-diol
MolbankParkinson’s disease (PD) is a progressive neurodegenerative disorder whose primary manifestation is motor dysfunction. Previous research showed that (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol (Prottremine) exhibits potent ...
Alexandra V. Podturkina +4 more
doaj +1 more source
Interdisciplinary Medicine, EarlyView.The sulfonated zwitterionic photosensitizer (PYSO3) is synthesized by reacting maleic anhydride derivatives with 4‐aminopyridine to form PY, followed by sulfonation with 1,4‐butane sultone. It exhibits both photothermal and photodynamic properties, enabling effective eradication of MRSA and biofilms, as well as promoting wound healing in mice ...
Changxu Zhu +10 more
wiley +1 more source
Stereo-Control in Zn(II) and Cd(II) Complexes of Tetraamines with Azacyclic Cores
InorganicsHalide-dictated stereoselective formation of octahedral Δ-cis-α-[Zn(L)Cl2] or trigonal bipyramidal Λ-[Zn(L)I]I, where L is a chiral tetramine with a pyrrolidine or piperidine core, has been observed in both the solid state and in solution through a ...
Hanan A. A. Althobaiti +5 more
doaj +1 more source
Antimicrobial Cyclic Peptidomimetics
Macromolecular Rapid Communications, EarlyView.Singular macromolecular cationic, amphipathic cyclic peptidomimetics with poly(2‐oxazoline)s‐esque backbone structure that undergo self‐assembly in water to form uniform nanoparticles were developed. The cyclic peptidomimetics, which act on bacterial cell membranes, exhibit hydrophobic‐dependent antimicrobial activity and toxicity.
Hao Luo, Edgar H. H. Wong
wiley +1 more source
Residual Chemical Shift Anisotropies in the Structure Determination of Small Molecules
Magnetic Resonance in Chemistry, EarlyView.Plasma neutrophil elastase(ELANE) was markedly elevated in patients with alcohol use disorder, indicating a dysregulated protease‐antiprotease inflammatory balance characterised by decreased SERPINA3. ELANE showed excellent diagnostic specificity(AUC = 0.8683), supporting its potential utility as a neuroinflammatory biomarker for AUD.
Nilamoni Nath +3 more
wiley +1 more source
Genetic variation of piperidine alkaloids in Pinus ponderosa: a common garden study [PDF]
, 2008 Elizabeth A. Gerson +2 more
openalex +1 more source
ChemistryOpen, EarlyView.Synthesized decapeptides were designed and validated by in silico studies. They have significantly exhibited anticancer potential against breast cancer and MCF‐7 cell line. The above illustration specifies the synthetic pathway, biological screening, and the mode of action of the peptide in blocking the pathways responsible for the growth of cancer ...
Sunil Tivari +7 more
wiley +1 more source