Common Mitochondrial DNA Mutations Generated through DNA-Mediated Charge Transport [PDF]
Mutation sites that arise in human mitochondrial DNA as a result of oxidation by a rhodium photooxidant have been identified. HeLa cells were incubated with [Rh(phi)2bpy]Cl3 (phi is 9,10-phenanthrenequinone diimine), an intercalating photooxidant, to ...
Barton, Jacqueline K.+2 more
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Ammonium piperidine-1-carbodithioate [PDF]
The title compound, NH(4) (+)·C(6)H(10)NS(2) (-), is composed of an ammonium cation and a piperidine-1-carbodithio-ate anion which exhibits positional disorder. The atoms of the ring have a structural disorder and they are divided into two sites, with occupancy factors of 0.584 and 0.426..
Maria Teresa do Prado Gambardella+1 more
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Use of apomorphine in Parkinsonian patients with neuropsychiatric complications to oral treatment [PDF]
Neuropsychiatric side effects often complicate anti-Parkinsonian therapy and pose a significant problem in the optimal management of idiopathic Parkinson's disease.
Abbott, R.J.+6 more
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Piperidin aus Pentamethylendiamin [PDF]
n ...
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Structures of piperazine, piperidine and morpholine [PDF]
The crystal structures of piperazine, piperidine and morpholine have been determined at 150 K. All three structures are characterized by the formation of NH...N hydrogen-bonded chains. In piperazine these are linked to form sheets, but the chains are shifted so that the molecules interleave. In morpholine there are in addition weak CH...O interactions.
Parkin, A, Oswald, I D H, Parsons, S
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Pivalolactone, 2. Copolyester synthesis via interchange reactions with polypivalolactone [PDF]
The synthesis of copolyesters via interchange reactions of polypivalolactone (PPVL) with several compounds was studied. The synthetical procedures are two-stage melt processes: in the first stage ester bonds in the polymer chain are cleaved and new ...
Bantjes, Adriaan+4 more
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Fat transforms ascorbic acid from inhibiting to promoting acid-catalysed N-nitrosation [PDF]
<b>Background</b>: The major potential site of acid nitrosation is the proximal stomach, an anatomical site prone to a rising incidence of metaplasia and adenocarcinoma.
Combet, E.+7 more
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Network-analysis-guided synthesis of weisaconitine D and liljestrandinine. [PDF]
General strategies for the chemical synthesis of organic compounds, especially of architecturally complex natural products, are not easily identified. Here we present a method to establish a strategy for such syntheses, which uses network analysis.
Gallego, GM+8 more
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Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3 [PDF]
Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment programs to combat TB are under threat due to the emergence of multi-drug and extensively-drug resistant TB.
A Hill+48 more
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