Results 31 to 40 of about 76,241 (267)

(7,8-Dimethyl-2-oxo-2H-chromen-4-yl)methyl piperidine-1-carbodithioate

open access: yesIUCrData, 2016
In the title compound, C18H21NO2S2, the 2H-chromene ring systems is nearly planar, with a maximum deviation of 0.023 (2) Å. The coumarin unit makes a dihedral angle of 60.54 (8)° with the piperidine ring, which adopts a chair conformation.
A. J. Ravi   +2 more
doaj   +1 more source

Regioselective ring opening of aziridine for synthesizing azaheterocycle

open access: yesFrontiers in Chemistry, 2023
Aziridine had different regioselective ring openings depending on the functional group of its alkyl substituent. In the case of the alkyl group bearing γ-ketone at the C2 substituent of aziridine, the ring opening by the hydroxy nucleophile from H2O ...
Nikhil Srivastava, Hyun-Joon Ha
doaj   +1 more source

Common Mitochondrial DNA Mutations Generated through DNA-Mediated Charge Transport [PDF]

open access: yes, 2009
Mutation sites that arise in human mitochondrial DNA as a result of oxidation by a rhodium photooxidant have been identified. HeLa cells were incubated with [Rh(phi)2bpy]Cl3 (phi is 9,10-phenanthrenequinone diimine), an intercalating photooxidant, to ...
Barton, Jacqueline K.   +2 more
core   +2 more sources

Pivalolactone, 2. Copolyester synthesis via interchange reactions with polypivalolactone [PDF]

open access: yes, 1993
The synthesis of copolyesters via interchange reactions of polypivalolactone (PPVL) with several compounds was studied. The synthetical procedures are two-stage melt processes: in the first stage ester bonds in the polymer chain are cleaved and new ...
Bantjes, Adriaan   +4 more
core   +4 more sources

Cobalt-Catalyzed (Hetero)arylation of Saturated Cyclic Amines with Grignard Reagents

open access: yesMolecules, 2018
(Hetero)aryl substituted saturated cyclic amines are ubiquitous scaffolds in biologically active molecules. Metal-catalyzed cross-couplings between halogeno N-heterocycles and organometallic species are efficient and modular reactions to access these ...
Baptiste Barré   +3 more
doaj   +1 more source

Sulfonamides with Heterocyclic Periphery as Antiviral Agents

open access: yesMolecules, 2022
Sulfonamides are the basic motifs for a whole generation of drugs from a large group of antibiotics. Currently, research in the field of the new sulfonamide synthesis has received a “second wind”, due to the increase in the synthetic capabilities of ...
Mikhail Yu. Moskalik
doaj   +1 more source

Network-analysis-guided synthesis of weisaconitine D and liljestrandinine. [PDF]

open access: yes, 2015
General strategies for the chemical synthesis of organic compounds, especially of architecturally complex natural products, are not easily identified. Here we present a method to establish a strategy for such syntheses, which uses network analysis.
Gallego, GM   +8 more
core   +2 more sources

Synthesis of Substituted α-Trifluoromethyl Piperidinic Derivatives

open access: yesMolecules, 2017
A comprehensive survey of pathways leading to the generation of α-trifluoromethyl monocyclic piperidinic derivatives is provided (65 references).
Sarah Rioton   +2 more
doaj   +1 more source

PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines

open access: yesBeilstein Journal of Organic Chemistry, 2011
PEG-embedded potassium tribromide ([K+PEG]Br3−) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and β-keto ester.
Sanny Verma, Suman L. Jain, Bir Sain
doaj   +1 more source

Crystal structure and Hirshfeld surface analysis of N-(4-nitrophenyl)-2-(piperidin-1-yl)acetamide (lidocaine analogue)

open access: yesActa Crystallographica Section E: Crystallographic Communications
In the title molecule, C13H17N3O3, the substituents on the phenyl ring are rotated slightly out of the mean plane of the ring but the piperidine moiety is nearly perpendicular to that plane. In the crystal, C—H...O hydrogen bonds form chains of molecules
Imane Maimoune   +7 more
doaj   +1 more source

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