Results 61 to 70 of about 37,707 (289)
Acta Crystallographica Section E: Crystallographic Communications, 2021 The title compounds, 8-{1-[3-(cyclopent-1-en-1-yl)benzyl]piperidin-4-yl}-2-methoxyquinoline, C27H30N2O (I), and 8-{4-[3-(cyclopent-1-en-1-yl)benzyl]piperazin-1-yl}-2-methoxyquinoline, C26H29N3O (II), differ only in the nature of the central six-membered ...
Nisar Ullah, Helen Stoeckli-Evans
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Advanced Science, EarlyView.Novel carbon‐11 labeled pyrimidine derivatives are developed as PET imaging probes for visualizing sigma‐1 receptors in the brain. [11C]CNY‐01 demonstrates superior brain uptake and binding specificity in both rodents and non‐human primates. The study reveals decreased sigma‐1 receptor expression in Alzheimer's disease, offering a promising tool for ...
Ping Bai +12 more
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Deprotection Reagents in Fmoc Solid Phase Peptide Synthesis: Moving Away from Piperidine?
Molecules, 2016 The deprotection step is crucial in order to secure a good quality product in Fmoc solid phase peptide synthesis. 9-Fluorenylmethoxycarbonyl (Fmoc) removal is achieved by a two-step mechanism reaction favored by the use of cyclic secondary amines ...
Omar F. Luna +5 more
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A General Strategy for C(sp3)─H Bond Etherification via Quinoline Derivative‐Mediated Electrolysis
Advanced Science, EarlyView.A quinoline‐based mediator is introduced for the electrochemical etherification of C(sp3)─H bonds, enabling the process with minimal dependence on substrate electronic properties. The reaction demonstrates compatibility with various C─H bonds, including tertiary benzylic C─H bonds and unactivated C(sp3)─H bonds.
Yousen Xu +4 more
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Crystal structure of the 1:2 adduct of bis(piperidinium) sulfate and 1,3-dimethylthiourea
Acta Crystallographica Section E: Crystallographic Communications, 2017 In the title compound, 2C5H12N+·SO42−·2C3H8N2S, the C=S groups of the two independent 1,3-dimethylurea molecules and the sulfur atom of the anion lie on twofold axes. The packing is centred on bis(piperidinium) sulfate ribbons parallel to the c axis; the
Cindy Döring +2 more
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Advanced Science, EarlyView.This study develops an Au/S‐doped reduced graphene oxide (Au@S‐rGO) sensor for rapid fentanyl detection. DFT simulations and structural analysis confirm atomically dispersed Au/S configurations, enhancing catalytic activity. The sensor achieves a 9.7 nmol L−1 detection limit, 98–104% recovery in human serum, and 85.7–93.6% consistency with mass ...
Meng Li +9 more
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Experimental and ab initio studies of the novel piperidine-containing acetylene glycols [PDF]
arXiv, 2015 Synthesis routes of novel piperidine-containing diacetylene are presented. The new molecules are expected to exhibit plant growth stimulation properties. In particular, the yield in a situation of drought is expected to increase. The synthesis makes use of the Favorskii reaction between cycloketones/piperidone and triple-bond containing glycols.
arxiv
Radical‐Polar Crossover Bicyclization Enables a Modular Synthesis of Saturated Bicyclic Amines
Advanced Science, EarlyView.Herein, we report the successful realization of a radical‐polar crossover bicyclization reaction from easily available cyclopropylamines and substituted alkenes through photoredox catalysis. This approach introduces an innovative methodology for the de novo synthesis of a diverse collection of 4/5‐, 5/5‐, 6/5‐,7/5‐ and 5/6‐fused saturated bicyclic ...
Dewei Feng +4 more
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An Organic Chemist's Guide to Mediated Laccase Oxidation
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 The mediator‐assisted laccase‐catalyzed oxidation of alcohols is a green alternative to established classical synthetic protocols. However, the interaction between laccases, mediators and oxygen comprises a highly complicated, multivariate system. We present a detailed comparative study evaluating the most important components and parameters via an ...
Katharina Obleser +5 more
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