Aromatic Nucleophilic Substitution. XIII. Confirmation of the Anionic σ Complexes in the Reactions of 2,4-Dinitro- and 2,4,5-Trinitro-1-(1-piperidyl)naphthalenes with Piperidine in Dimethyl Sulfoxide [PDF]
Shizen Sekiguchi +5 more
openalex +1 more source
Piperidine alkaloids of Norway spruce (Picea abies L. Karsten) : Relations with genotypes, season, environment and phenolics [PDF]
Virjamo, Virpi
core
KOtBu‐promoted facile and practical synthesis of various substituted piperidine‐2,6‐diones between methyl acetates and acrylamides via a Michael addition/intramolecular imidation cascade sequence has been disclosed. And reaction scale‐up, further transformation of representative products, and preparation of bioactive molecules (e. g.
Yue‐Hua Liu +7 more
wiley +1 more source
Stereocontrolled synthesis of 3-hydroxy-2-piperidinone carboxamides by catalytic ring-opening aminolysis of bridged <i>δ</i>-lactam-γ-lactones. [PDF]
Beng TK +4 more
europepmc +1 more source
Synthesis and Pharmacology of N-Substituted-4-(p-Metboxypbenyl) Piperidine-2,6-diones [PDF]
S. D. SAMANT, K. D. DEODHAR
openalex +1 more source
A library of easily synthesizable CAPE analogs was screened in silico against the dengue virus envelope protein. Compound LQM778 showed stable binding and promising inhibitory potential. This study highlights LQM778 as a candidate for future in vitro validation and structural optimization toward accessible antiviral agents against dengue.
Luis Alfonso Cárdenas‐Granados +9 more
wiley +1 more source
Novel Potent and Selective Dopamine D4 Receptor Piperidine Antagonists as Potential Alternatives for the Treatment of Glioblastoma. [PDF]
Matteucci F +16 more
europepmc +1 more source
Chemoenzymatic Synthesis of Chiral 1-Benzyl-5-(hydroxymethyl)- 2-piperidone Enabled by Lipase AK-Mediated Desymmetrization of Prochiral 1,3-Diol and Its Diacetate [PDF]
Gallagher, Timothy +3 more
core +1 more source
N‐terminal betaine conjugation modifies β‐peptide helices, influencing folding and self‐organization. For [1S, 2S]‐ACPC, folding to an H12 helix was unaffected, while [1R, 2R]‐ACHC formed an H14 helix instead of H10. Alternating heterochiral oligomers made of enantiomeric pairs of trans‐ACPC showed enhanced solubility and E‐strand formation.
Nikolett Varró +10 more
wiley +1 more source

