Results 251 to 260 of about 40,506 (345)

Structure-activity relationship of 3- and 4-acyloxy-1-(1,3-dioxolan-4-ylmethyl)piperidine derivatives.

, 1985
S. Yoshida, SABURO SUGAI, Yoshio Kajiwara, Tomie Kawada, TOSHIFUMI KANBARA, Yasuo Naito, Yoshihiro Hasegawa, Sanya Akaboshi, TERUO KUTSUMA, Hiroshi Ikawa, NORIHIRO KATSUHARA, Yasufumi Terawaki, Issei Takayanagi   +12 more
openalex   +2 more sources

The Therapeutic Potential of Spirooxindoles in Cancer: A Focus on p53-MDM2 Modulation. [PDF]

Pharmaceuticals (Basel)
Girgis AS, Zhao Y, Nkosi A, Ismail NSM, Bekheit MS, Aboshouk DR, Aziz MN, Youssef MA, Panda SS.   +8 more
europepmc   +1 more source

High‐throughput screen identifies MAS9 as a novel inhibitor of the C‐type lectin receptor‐2 (CLEC‐2)–podoplanin interaction

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The C‐type lectin‐like receptor‐2 (CLEC‐2) is a platelet receptor for the endogenous ligand podoplanin. This interaction contributes to several (patho)physiological processes, such as lymphangiogenesis, preservation of blood and lymphatic vessel integrity organ development, and tumour metastasis.
Marcin A. Sowa, Yan Wu, Jan van Groningen, Ying Di, Helma van den Hurk, Johannes A. Eble, Jonathan M. Gibbins, Ángel García, Alice Y. Pollitt   +8 more
wiley   +1 more source

Recurrence of chronic lymphatic leukemia as infiltration of the spinal cord. [PDF]

J Med Life
Finsterer J, Rathkolb V.
europepmc   +1 more source

Unlocking the power of immune checkpoint inhibitors: Targeting YAP1 reduces anti‐PD1 resistance in skin cutaneous melanoma

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors, such as anti­PD1, revolutionized melanoma treatment. However, resistance and low response rates remain problems. Our goal was to pinpoint actionable biomarkers of resistance to anti‐PD1 treatment and verify therapeutic effectiveness in vivo.
Szonja Anna Kovács, Tamás Kovács, András Lánczky, Ágnes Paál, Zsombor I. Hegedűs, Nabil V. Sayour, Lilla Szabó, Andrea Kovács, Giampaolo Bianchini, Péter Ferdinandy, Alberto Ocana, Zoltán V. Varga, János Tibor Fekete, Balázs Győrffy   +13 more
wiley   +1 more source

An effective strategy with tofacitinib for the management of focal myositis with rheumatoid arthritis: a case report. [PDF]

Front Immunol
Pan J, Zheng H, Xu J, Pan S.
europepmc   +1 more source

Design and methodology of the harmonized diagnostic assessment of dementia for the longitudinal aging study in India: Wave 2

Journal of the American Geriatrics Society, Volume 73, Issue 3, Page 685-696, March 2025.
Abstract The rising burden of dementia calls for high‐quality data on cognitive decline and dementia onset. The second wave of the Harmonized Diagnostic Assessment for the Longitudinal Aging Study in India (LASI‐DAD) was designed to provide longitudinal assessments of cognition and dementia in India.
Pranali Y. Khobragade, Sarah Petrosyan, Sharmistha Dey, A. B. Dey, Jinkook Lee, on behalf of the LASI‐DAD Authorship Team, Pranali Y. Khobragade, Sarah Petrosyan, Albert Weerman, Peifeng Hu, Alden L. Gross, Joyita Banerjee, Sandy Chien, Marco Angrisani, Sara D. Adar, Leon Aksman, Niranjan Khandelwal, Anushikha Dhankhar, Harrshita Vishwakarrma, Swaroop Bhatankar, Swati Bajpai, Istikhar Ali, Masroor Anwar, Abhishek Gupta, Clarice Myers, Alka Mohan Chutani, Claire McEvoy, Danielle E. Logan, Kirsten Lynch, Ziqi Zhou, Emma Nichols, Rajeev Aravindakshan, Sankha Subhra Chakrabarti, Madhumita Priyadarshini Das, Karishma De, Minakshi Dhar, Gevesh C. Dewangan, Monica Gupta, Umar Hafiz Khan, Vishakha Jain, John P. John, Ravi Kirti, Arun Kokane, Sarabmeet Singh Lehl, Rashmi R. Mohanty, Vinay Pandit, Chhaya Rajguru, Durgesh Prasad Sahoo, Lalit Sankhe, M. Sukumar, Arunansu Talukdar, Venugopalan Gunasekaran, Joshua R. Ehrich, Elissa S. Epel, David Flood, T. V. Sekher, David E. Bloom, Kenneth M. Langa, Palanimuthu T. Sivakumar, Mathew Varghese, Mary Ganguli, Bharat Thyagarajan, Eileen M. Crimmins, Sharmistha Dey, A. B. Dey, Jinkook Lee   +65 more
wiley   +1 more source

t(14;22)(q32;q11) translocation involving IGH and IGL acquired at progression of splenic marginal zone lymphoma treated with rituximab, ibrutinib, and obinutuzumab. [PDF]

Ann Hematol
Geyer JT, Ruan J, Kluk MJ, Bao L.
europepmc   +1 more source

Managing Hypercholesterolemia in Adults Older Than 75 years Without a History of Atherosclerotic Cardiovascular Disease: An Expert Clinical Consensus From the National Lipid Association and the American Geriatrics Society

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT The risk of atherosclerotic cardiovascular disease increases with advancing age. Elevated LDL‐cholesterol and non‐HDL‐cholesterol levels remain predictive of incident atherosclerotic cardiovascular events among individuals older than 75 years.
Vera Bittner, Sunny A. Linnebur, Dave L. Dixon, Daniel E. Forman, Ariel R. Green, Terry A. Jacobson, Ariela R. Orkaby, Joseph J. Saseen, Salim S. Virani   +8 more
wiley   +1 more source

JAK Inhibitors: A Double-Edged Sword in Immune-Mediated Diseases Management. [PDF]

United European Gastroenterol J
Bertin L, Savarino EV.
europepmc   +1 more source