Results 21 to 30 of about 5,094 (194)
Scientific Reports, 2022 Organophosphorus (OP) compounds that inhibit acetylcholinesterase are a common cause of poisoning worldwide, resulting in several hundred thousand deaths each year.
Oksana A. Lenina, Konstantin A. Petrov
doaj +1 more source
ESC Heart Failure, Volume 10, Issue 6, Page 3311-3329, December 2023., 2023 Abstract Aims We aim to explore the role and mechanism of vagus nerve stimulation (VNS) in coronary endothelial cells and angiogenesis in infarcted hearts. Methods and results Seven days after rat myocardial infarction (MI) was prepared by ligation of the left anterior descending coronary artery, the left cervical vagus nerve was treated with ...
Yan Wang +14 more
wiley +1 more source
Clozapine for the treatment of aggressiveness and agitation in advanced dementia
Psychogeriatrics, Volume 23, Issue 6, Page 963-972, November 2023., 2023 Abstract Background Distressing behavioural symptoms, particularly agitation and aggressiveness, remain a difficult problem in everyday clinical practice in the treatment of multimorbid patients with dementia. Clozapine may be an effective therapeutic alternative in this context.
Arwed E. Michael +3 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
British Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander +165 more
wiley +1 more source
Additive interaction of intrathecal ginsenosides and neostigmine in the rat formalin test [PDF]
Korean Journal of Anesthesiology, 2013 BackgroundThe authors evaluated the effect of intrathecal mixture of ginsenosides with neostigmine on formalin-induced nociception and made further clear the role of the spinal muscarinic (M) receptors on the activity of ginsenosides.MethodsA catheter ...
Cheon-Hee Park +3 more
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The 100 Most Frequently Cited Articles on Myopia
Journal of Ophthalmology, Volume 2023, Issue 1, 2023., 2023 Purpose. To provide a bibliographical‐historical perspective and main interest in the field of myopia. Methods. In this bibliographic study, the Web of Science Database was searched from 1999 to 2018. Recorded parameters included journal name, impact factor, year and language, number of authors, type and origin, methodology, number of subjects, funding,
Rachel Shemesh +4 more
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Di-san junyi daxue xuebao, 2021 Objective To determine the effect of muscarinic acetylcholine M1 receptor (CHRM1) on pyroptosis of prostate cancer cells and investigate its possible molecular mechanism. Methods Pirenzepine (PIN), a specific CHRM1 antagonist, and bethanechol (BETH), its
CHEN Jinying +6 more
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Dynamic regulation of quaternary organization of the M1 muscarinic receptor by subtype-selective antagonist drugs [PDF]
, 2016 Although rhodopsin-like G protein-coupled receptors can exist as both monomers and non-covalently associated dimers/oligomers, the steady-state proportion of each form and whether this is regulated by receptor ligands is unknown.
Godin, Antoine G. +4 more
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Corticosteroids in patients with vestibular neuritis: An updated meta‐analysis
Acta Neurologica Scandinavica, Volume 146, Issue 5, Page 429-439, November 2022., 2022 Vestibular neuritis is a common neuro‐otological entity. Therapeutically, corticosteroids are advised, although the evidence is limited. The objective of this review is to update meta‐analyses of clinical trials that address the question of whether patients with vestibular neuritis treated with corticosteroids show better recovery than control patients.
Anna Bogdanova +3 more
wiley +1 more source
Cooperative Glutamatergic and Cholinergic Mechanisms Generate Short-Term Modifications of Synaptic Effectiveness in Prepositus Hypoglossi Neurons [PDF]
, 2005 To maintain horizontal eye position on a visual target after a saccade, extraocular motoneurons need a persistent (tonic) neural activity, called "eye-position signal," generated by prepositus hypoglossi (PH) neurons.
Delgado-Garcia, JM +2 more
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