Results 31 to 40 of about 5,364 (186)

Additive interaction of intrathecal ginsenosides and neostigmine in the rat formalin test [PDF]

Korean Journal of Anesthesiology, 2013
BackgroundThe authors evaluated the effect of intrathecal mixture of ginsenosides with neostigmine on formalin-induced nociception and made further clear the role of the spinal muscarinic (M) receptors on the activity of ginsenosides.MethodsA catheter ...
Cheon-Hee Park, Park-Ne Kim, Seong-Heon Lee, Myung Ha Yoon   +3 more
doaj   +1 more source

Corticosteroids in patients with vestibular neuritis: An updated meta‐analysis

Acta Neurologica Scandinavica, Volume 146, Issue 5, Page 429-439, November 2022., 2022
Vestibular neuritis is a common neuro‐otological entity. Therapeutically, corticosteroids are advised, although the evidence is limited. The objective of this review is to update meta‐analyses of clinical trials that address the question of whether patients with vestibular neuritis treated with corticosteroids show better recovery than control patients.
Anna Bogdanova, Julia Dlugaiczyk, Josef Georg Heckmann, Stefan Schwab   +3 more
wiley   +1 more source

Muscarinic receptors in the rat ovary are involved in follicular development but not in steroid secretion

Physiological Reports, Volume 10, Issue 21, November 2022., 2022
Role of Acetylcholine in steroid biosynthesis and follicular development in the rat ovary. The follicles of the rat ovary do not receive a direct extraovarian cholinergic innervation. It mainly originated from an intraovarian source of Acetylcholine (a).
Fernanda C. Cuevas, Daniela Bastias, Constanza Alanis, Agustin Benitez, Valentina Squicciarini, Raul Riquelme, Pia Sessenhausen, Artur Mayerhofer, Hernan E. Lara   +8 more
wiley   +1 more source

Effects of Mlx-8, a phospholipase A2 from Brazilian coralsnake Micrurus lemniscatus venom, on muscarinic acetylcholine receptors in rat hippocampus [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2020
Background: Here, we described the presence of a neurotoxin with phospholipase A2 activity isolated from Micrurus lemniscatus venom (Mlx-8) with affinity for muscarinic acetylcholine receptors (mAChRs).
Roberta Tancredi Francesco dos Santos, Marcelo Florencio Passos Silva, Rafael Marques Porto, Ivo Lebrun, Luís Roberto de Camargo Gonçalves, Isabel de Fátima Correia Batista, Maria Regina Lopes Sandoval, Fernando Maurício Francis Abdalla   +7 more
doaj   +1 more source

The activation of M2 muscarinic receptor inhibits cell growth and survival in human epithelial ovarian carcinoma

Journal of Cellular Biochemistry, Volume 123, Issue 9, Page 1440-1453, September 2022., 2022
Abstract Ovarian cancer is the fifth leading cause of cancer‐related deaths in females. Many ovarian tumor cell lines express muscarinic receptors (mAChRs), and their expression is correlated with reduced survival of patients. We have characterized the expression of mAChRs in two human ovarian carcinoma cell lines (SKOV‐3, TOV‐21G) and two immortalized
Marilena Taggi, Andjela Kovacevic, Chiara Capponi, Marta Falcinelli, Veronica Cacciamani, Elena Vicini, Rita Canipari, Ada Maria Tata   +7 more
wiley   +1 more source

Pharmacological and molecular characterization of the A‐type muscarinic acetylcholine receptor from Anopheles gambiae

Insect Molecular Biology, Volume 31, Issue 4, Page 497-507, August 2022., 2022
A‐type mAChR was identified in Anopheles gambiae larvae and adult mosquitoes Activation of An. gambiae mAChR‐A which is coupled to phosphoinositide pathway induced intracellular calcium increase An. gambiae mAChR‐A is mainly blocked by 4‐DAMP known as M3 mAChR antagonist in mammals Summary showing the pharmacology of Anopheles gambiae mAChR‐A and its ...
Alexandre Pilon, Delphine Goven, Valerie Raymond   +2 more
wiley   +1 more source

Interaction between Pirenzepine and Ninjinto, a Traditional Japanese Herbal Medicine, on the Plasma Gut-Regulated Peptide Levels in Humans

International Journal of Peptides, 2013
The Japanese herbal medicine (Kampo) Ninjinto has been used for the treatment of gastroenteritis, esogastritis, gastric atony, gastrectasis, vomiting, and anorexia.
Y. Sato, I. Hiroki, Yosuke Suzuki, R. Tatsuta, M. Takeyama   +4 more
semanticscholar   +1 more source

Cholinergic Regulation of Orexin/Hypocretin Neurons Through M3Muscarinic Receptor in Mice

Journal of Pharmacological Sciences, 2008
The cholinergic system plays an important role in regulation of arousal and REM sleep. In the present study, we showed that a muscarinic receptor agonist, carbachol (CCh), activates almost 20% of orexin-producing neurons (orexin neurons), which play a ...
Kousaku Ohno, Mari Hondo, Takeshi Sakurai   +2 more
doaj   +1 more source

Traditional Chinese medicine could play an important role in diabetes management: Commentary on "National Chinese medicine guideline for the prevention and treatment of diabetes in primary care (2022)". [PDF]

J Diabetes
Journal of Diabetes, Volume 16, Issue 4, April 2024.
Jia L, Shen C, Lai B, Huang C, Zhao N, Li B, Zhang Z, Cai M, Yan B, Liu J, Yang S.   +10 more
europepmc   +2 more sources

Muscarinic acetylcholine receptor M1 mediates prostate cancer cell migration and invasion through hedgehog signaling

Asian Journal of Andrology, 2018
The autonomic nervous system contributes to prostate cancer proliferation and metastasis. However, the exact molecular mechanism remains unclear. In this study, muscarinic acetylcholine receptor M1 (CHRM1) expression was measured via immunohistochemical ...
Qing-Qing Yin, Lin-Hui Xu, Mi Zhang, Chen Xu   +3 more
doaj   +1 more source