Results 81 to 90 of about 5,094 (194)

Behavioral effects of Bj-PRO-7a, a proline-rich oligopeptide from Bothrops jararaca venom [PDF]

open access: yesBrazilian Journal of Medical and Biological Research
The heptapeptide Bj-PRO-7a, isolated and identified from Bothrops jararaca (Bj) venom, produces antihypertensive and other cardiovascular effects that are independent on angiotensin converting enzyme inhibition, possibly relying on cholinergic muscarinic
L.C. Turones   +11 more
doaj   +2 more sources

Efectos de la pirenzepina sobre células parietales en regeneración [PDF]

open access: yes, 1990
In this work, we have carrled out a stereological and ultrastructural study in order to verify the action of Pirenzepine on regenerating parietal cells.
Ibáñez Delgado, Francisco   +3 more
core  

Identification of novel therapeutics for complex diseases from genome-wide association data [PDF]

open access: yes, 2014
Background: Human genome sequencing has enabled the association of phenotypes with genetic loci, but our ability to effectively translate this data to the clinic has not kept pace.
Ballouz, S.   +6 more
core   +1 more source

Human HT-29 colon carcinoma cells contain mucarinic M\(_3\) receptors coupled to phosphoinositide metabolism [PDF]

open access: yes, 1989
Five different musearlnie receptor subtypes ean be distinguished by the differenees in their amino aeid sequence, the eoupled signal transduetion system, pharmaeologieal binding properties and aetivation of ionie fluxes.
Kopp, R.   +5 more
core  

Duration judgements in patients with schizophrenia [PDF]

open access: yes, 2003
Background. The ability to encode time cues underlies many cognitive processes. In the light of schizophrenic patients' compromised cognitive abilities in a variety of domains, it is noteworthy that there are numerous reports of these patients displaying
Brown, G. D. A. (Gordon D. A.)   +5 more
core   +1 more source

Effects of AF-DX116 and Other Muscarinic Receptor Antagonists on Orthostatic Hypotension in Autonomic Imbalanced (SART-Stressed) Rats

open access: yesJournal of Pharmacological Sciences, 2005
SART (specific alternation of rhythm in temperature)-stressed rats are an animal model of autonomic imbalance created by exposing animals to repeated cold stress. The SART-stressed rats have been shown to easily develop orthostatic hypotension (OH).
Taeko Hata   +2 more
doaj   +1 more source

Novel aspects of cholinergic regulation of colonic ion transport [PDF]

open access: yes, 2015
Nicotinic receptors are not only expressed by excitable tissues, but have been identified in various epithelia. One aim of this study was to investigate the expression of nicotinic receptors and their involvement in the regulation of ion transport across
Bader, Sandra, Diener, Martin
core   +1 more source

Effect of Mutated Cu, Zn Superoxide Dismutase (SOD1G93A) on Modulation of Transductional Pathway Mediated by M1 Muscarinic Receptor in SK-N-BE and NSC-34 Cells

open access: yesFrontiers in Physiology, 2018
The constitutive secretion of antioxidant Cu-Zn Superoxide dismutase (SOD1) has been widely demonstrated in many cellular lines. In addition, we showed that as well as the basal SOD1 secretion, this enzyme is also exported through depolarization of ...
Simona Damiano   +8 more
doaj   +1 more source

Traditional Chinese medicine could play an important role in diabetes management: Commentary on “National Chinese medicine guideline for the prevention and treatment of diabetes in primary care (2022)”

open access: yes
Journal of Diabetes, Volume 16, Issue 4, April 2024.
Liyan Jia   +10 more
wiley   +1 more source

On the Mechanisms Underlying Histamine Induction of Gastric Mucosal Lesions in Rats With Partial Gastric Vascular Occlusion

open access: yesJournal of Pharmacological Sciences, 2003
Although it is well known that histamine induces gastric mucosal lesions in laboratory animals, the fundamental mechanisms remain unclear. In order to further analyze the vascular mechanisms underlying histamine-induced lesions, a new model was developed
Kikuko Amagase, Susumu Okabe
doaj   +1 more source

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