Dissolution enhancement of gliclazide using pH change approach in presence of twelve stabilizers with various physico-chemical properties [PDF]
Purpose. The micronization using milling process to enhance dissolution rate is extremely inefficient due to a high energy input, and disruptions in the crystal lattice which can cause physical or chemical instability.
Mostafavi, Seyed Abolfazl +3 more
core +2 more sources
Photocatalyzed Ring Expansion of α‐Ketosulfonylaziridines: Ready Access to δ‐Sultams
A novel radical–polar crossover (RPC) photoredox‐catalyzed reaction for the synthesis of δ‐sultams from N‐sulfonyl α‐ketoaziridines through a controlled ring opening–expansion process is presented. This method allows the easy access to sultams with an unprecedented substitution pattern in up to 85% yield and 2:1 d.r., and highlights the potential of ...
Marco M. Mastandrea +7 more
wiley +2 more sources
Counterion Effects on Nano-confined Metal-Drug-DNA Complexes
We have explored morphology of DNA molecules bound with Cu-complexes of piroxicam molecules, a non-steroidal anti-inflammatory drug (NSAID), under one-dimensional confinement of thin films and have studied the effect of counterions present in a buffer. X-
Bera, Mrinal K. +6 more
core +2 more sources
Role of vascular mechanisms involved in the acute gastric mucosal injury induced by droxicam and piroxicam in rats [PDF]
We describe the formation of severe gastric erosions produced in fasted rats by intragastric administration of droxicam and its active species piroxicam, non-steroidal anti-inflammatory drugs of the oxicam group.
Alarcón de la Lastra Romero, Catalina +6 more
core +1 more source
Piroxicam is a common painkiller and anti-inflammatory drug. Precise monitoring of piroxicam levels can mitigate side effects, but current methods are often slow and complicated. An easily fabricated and highly sensitive voltammetric sensor for piroxicam
Jin LI +9 more
doaj +1 more source
In the present study piroxicam loaded starch nanoparticles were prepared to enhance the solubility of piroxicam by nanoprecipitation technique. The preparation of nanoparticles was carried out as per central composite experimental design protocol, having
Meenakshi Bhatia, Sulekha Rohilla
doaj +1 more source
Formulation and Characterization of Piroxicam as Self-Nano Emulsifying Drug Delivery System
Piroxicam (PIR) is a nonsteroidal anti-inflammatory drug of oxicam category, used in gout, arthritis, as well as other inflammatory conditions (topically and orally).
Fahad F. Salim, Nawal A. Rajab
doaj +1 more source
Use of Non-Steroidal Anti-Inflammatory Drugs That Elevate Cardiovascular Risk: An Examination of Sales and Essential Medicines Lists in Low-, Middle-, and High-Income Countries [PDF]
PMCID: PMC3570554This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Dans +20 more
core +3 more sources
Kristalne modifikacije i profil oslobađanja piroksikama [PDF]
Piroxicam is a nonsteroidal anti-inflammatory drug with low aqueous solubility which exhibits polymorphism. The present study was carried out to develop polymorphs of piroxicam with enhanced solubility and dissolution rate by the crystal modification ...
A. Rajendarn +19 more
core +2 more sources
Probable cutaneous adverse drug reaction to piroxicam in a cat
Case summary A 9-year-old male neutered Devon Rex cat presented with bilaterally symmetrical ulcerative lesions with mucopurulent exudate that developed rapidly. The lesions were apparent on the axillae, ventral abdomen and inguinal areas.
Amanda J Young +2 more
doaj +1 more source

