Results 31 to 40 of about 17,854 (186)

Dissolution enhancement of gliclazide using pH change approach in presence of twelve stabilizers with various physico-chemical properties [PDF]

open access: yes, 2009
Purpose. The micronization using milling process to enhance dissolution rate is extremely inefficient due to a high energy input, and disruptions in the crystal lattice which can cause physical or chemical instability.
Mostafavi, Seyed Abolfazl   +3 more
core   +2 more sources

Photocatalyzed Ring Expansion of α‐Ketosulfonylaziridines: Ready Access to δ‐Sultams

open access: yesAngewandte Chemie, Volume 138, Issue 4, 22 January 2026.
A novel radical–polar crossover (RPC) photoredox‐catalyzed reaction for the synthesis of δ‐sultams from N‐sulfonyl α‐ketoaziridines through a controlled ring opening–expansion process is presented. This method allows the easy access to sultams with an unprecedented substitution pattern in up to 85% yield and 2:1 d.r., and highlights the potential of ...
Marco M. Mastandrea   +7 more
wiley   +2 more sources

Counterion Effects on Nano-confined Metal-Drug-DNA Complexes

open access: yes, 2016
We have explored morphology of DNA molecules bound with Cu-complexes of piroxicam molecules, a non-steroidal anti-inflammatory drug (NSAID), under one-dimensional confinement of thin films and have studied the effect of counterions present in a buffer. X-
Bera, Mrinal K.   +6 more
core   +2 more sources

Role of vascular mechanisms involved in the acute gastric mucosal injury induced by droxicam and piroxicam in rats [PDF]

open access: yes, 1997
We describe the formation of severe gastric erosions produced in fasted rats by intragastric administration of droxicam and its active species piroxicam, non-steroidal anti-inflammatory drugs of the oxicam group.
Alarcón de la Lastra Romero, Catalina   +6 more
core   +1 more source

Fabrication of Sensitive Voltammetric Sensors and Microsensors for Piroxicam by Modifying Nafion and MWCNTs Composite Film on the Electrode Surface

open access: yesElectrochemistry
Piroxicam is a common painkiller and anti-inflammatory drug. Precise monitoring of piroxicam levels can mitigate side effects, but current methods are often slow and complicated. An easily fabricated and highly sensitive voltammetric sensor for piroxicam
Jin LI   +9 more
doaj   +1 more source

Formulation and optimization of quinoa starch nanoparticles: Quality by design approach for solubility enhancement of piroxicam

open access: yesSaudi Pharmaceutical Journal, 2020
In the present study piroxicam loaded starch nanoparticles were prepared to enhance the solubility of piroxicam by nanoprecipitation technique. The preparation of nanoparticles was carried out as per central composite experimental design protocol, having
Meenakshi Bhatia, Sulekha Rohilla
doaj   +1 more source

Formulation and Characterization of Piroxicam as Self-Nano Emulsifying Drug Delivery System

open access: yesIraqi Journal of Pharmaceutical Sciences, 2020
Piroxicam (PIR) is a nonsteroidal anti-inflammatory drug of oxicam category, used in gout, arthritis, as well as other inflammatory conditions (topically and orally).
Fahad F. Salim, Nawal A. Rajab
doaj   +1 more source

Use of Non-Steroidal Anti-Inflammatory Drugs That Elevate Cardiovascular Risk: An Examination of Sales and Essential Medicines Lists in Low-, Middle-, and High-Income Countries [PDF]

open access: yes, 2013
PMCID: PMC3570554This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Dans   +20 more
core   +3 more sources

Kristalne modifikacije i profil oslobađanja piroksikama [PDF]

open access: yes, 2011
Piroxicam is a nonsteroidal anti-inflammatory drug with low aqueous solubility which exhibits polymorphism. The present study was carried out to develop polymorphs of piroxicam with enhanced solubility and dissolution rate by the crystal modification ...
A. Rajendarn   +19 more
core   +2 more sources

Probable cutaneous adverse drug reaction to piroxicam in a cat

open access: yesJournal of Feline Medicine and Surgery Open Reports, 2018
Case summary A 9-year-old male neutered Devon Rex cat presented with bilaterally symmetrical ulcerative lesions with mucopurulent exudate that developed rapidly. The lesions were apparent on the axillae, ventral abdomen and inguinal areas.
Amanda J Young   +2 more
doaj   +1 more source

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