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The Hypothalamic-Pituitary-Adrenal Axis: Development, Programming Actions of Hormones, and Maternal-Fetal Interactions

open access: yesFrontiers in Behavioral Neuroscience, 2021
The hypothalamic-pituitary-adrenal axis is a complex system of neuroendocrine pathways and feedback loops that function to maintain physiological homeostasis.
Julietta A. Sheng   +7 more
doaj   +1 more source

Pituitary-immune bidirectional crosstalk under systemic inflammation.

open access: yesPLoS Biology, 2023
The pituitary gland responds to and modulates immune stress through the hypothalamus-pituitary-adrenal axis. A new study in PLOS Biology reveals unconventional bidirectional communication between hormone-producing cells and the immune system upon ...
Qingyun Li
doaj   +1 more source

Non-Canonical Effects of ACTH: Insights Into Adrenal Insufficiency

open access: yesFrontiers in Endocrinology, 2021
IntroductionAdrenocorticotropic hormone (ACTH) is produced from proopiomelanocortin, which is predominantly synthetized in the corticotroph and melanotroph cells of the anterior and intermediate lobes of the pituitary gland and the arcuate nucleus of the
Valeria Hasenmajer   +5 more
doaj   +1 more source

Modeling pulsativity in the hypothalamic–pituitary–adrenal hormonal axis

open access: yesScientific Reports, 2022
A new mathematical model for biological rhythms in the hypothalamic–pituitary–adrenal (HPA) axis is proposed. This model takes the form of a system of impulsive time-delay differential equations which include pulsatile release of adrenocorticotropin ...
Alexander N. Churilov, John G. Milton
doaj   +1 more source

Urbanicity, biological stress system functioning and mental health in adolescents.

open access: yesPLoS ONE, 2020
Growing up in an urban area has been associated with an increased chance of mental health problems in adults, but less is known about this association in adolescents.
Brittany E Evans   +5 more
doaj   +1 more source

Late-onset hypophysitis after discontinuation of nivolumab treatment for advanced skin melanoma: a case report

open access: yesBMC Endocrine Disorders, 2021
Background Nivolumab is an anti-programmed cell death protein 1 antibody, typically used as cancer immunotherapy agent. Despite multiple clinical benefits it might cause autoimmune-related side-effects, often involving the endocrine system.
Sofia Antoniou   +4 more
doaj   +1 more source

INTERACTIONS BETWEEN MASTICATION AND STRESS [PDF]

open access: yesRomanian Medical Journal, 2018
The main neuroendocrine response to stress is via activation of the hypothalamic-pituitary-adrenal (HPA) axis that contribute to the release of glucocorticoid hormone and ACTH.
Andrei Kozma   +3 more
doaj   +1 more source

The Stress Axis in Obesity and Diabetes Mellitus: An Update

open access: yesEndocrines, 2021
The hypothalamic–pituitary–adrenal axis is a tightly regulated system that represents one of the body’s mechanisms for responding to acute and chronic stress.
Laura Gianotti   +3 more
doaj   +1 more source

Functional state of the pituitary-adrenal system in women with rheumatism

open access: yesZaporožskij Medicinskij Žurnal, 2018
Objective: to study peculiarities of the pituitary-adrenal system reactivity during pregnancy and delivery in women suffering from rheumatism depending on the rheumatoid process activity and heart failure (HF) degree.
S. Ye. Kosilova
doaj   +1 more source

The Effect of High Dose Total Body Irradiation on ACTH, Corticosterone, and Catecholamines in the Rat [PDF]

open access: yes, 2011
Total body irradiation (TBI) or partial body irradiation is a distinct risk of accidental, wartime, or terrorist events. Total body irradiation is also used as conditioning therapy before hematopoietic stem cell transplantation.
Bruder, Eric D.   +4 more
core   +2 more sources

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