Results 91 to 100 of about 627,391 (362)

Management of Acromegaly With Pasireotide LAR: A Case Study of Sustained Biochemical Control and Tumor Volume Reduction Without Worsening of Glycemia

open access: yesAACE Clinical Case Reports, 2016
: Objective: Pasireotide long-acting release (LAR), a next-generation, multireceptor-targeted somatostatin analogue with high binding affinity to somatostatin receptor type 5, has been shown to be superior to octreotide LAR in inducing biochemical ...
Kevin C.J. Yuen, MD, FRCP (UK)
doaj   +1 more source

Translational Windows in Chordoma: A Target Appraisal

open access: yesFrontiers in Neurology, 2020
Chordomas are rare tumors that are notoriously refractory to chemotherapy and radiotherapy when radical surgical resection is not achieved or upon recurrence after maximally aggressive treatment.
Samantha E. Hoffman   +6 more
doaj   +1 more source

On‐Device Brain Tumor Classification from MR Images Using Smartphone

open access: yesAdvanced Intelligent Systems, EarlyView.
Herein, various deep learning models are trained for brain tumor classification task, and model performances are compared. The performance is further improved by using the proposed preprocessing algorithm before training. The MobileViT model, which is the best‐performing model in terms of balance between inference time and success rate, is integrated ...
Halil Ibrahim Ustun   +3 more
wiley   +1 more source

Ensemble Deep Learning Approach for Brain Tumor Classification Using Vision Transformer and Convolutional Neural Network

open access: yesAdvanced Intelligent Systems, EarlyView.
This study proposes a deep learning‐based system for classifying brain tumors from magnetic resonance imaging images. Four datasets were created using various wavelet transforms and original images. Several convolutional neural network and vision transformer models were trained via transfer learning, and an ensemble of top models achieved 85.03 ...
Ismail Oztel
wiley   +1 more source

Acromegaly: pathogenesis & treatment [PDF]

open access: yes, 2019
Acromegaly is a multi-system disorder whose etiology is most often traced back to a growth hormone-secreting pituitary adenoma (PA). Growth hormone (GH) secretion promotes insulin-like growth factor 1 (IGF-1) release from peripheral tissues, leading to ...
Tilvawala, Megha
core  

The Role of RFamide-Related Peptide-3 in Age-Related Reproductive Decline in Female Rats. [PDF]

open access: yes, 2016
Reproductive senescence, the point in time when females cease to show estrous cyclicity, is associated with endocrine changes in the hypothalamus, pituitary, and gonads. However, the mechanisms triggering this transition are not well understood.
Bentley, George E   +4 more
core   +1 more source

Pituitary tuberculoma

open access: yesJournal of Neurosciences in Rural Practice, 2010
ABSTRACTTuberculosis of pituitary gland is rare. We report a case of tuberculosis of pituitary gland in a 68-year-old male presented with holocranial headache of four months duration with left temporal hemianopia, with visual acuity of 6/6, without any localizing sign.
Shukla, S   +3 more
openaire   +2 more sources

Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Peter Valent   +27 more
wiley   +1 more source

3D Facial Analysis in Acromegaly: Gender-Specific Features and Clinical Correlations

open access: yesFrontiers in Endocrinology, 2018
Objective: Quantitative investigations of facial changes in acromegaly are rare. A new imaging technique, three-dimensional (3D) stereophotography, can accurately quantify whole facial changes.
Xiaopeng Guo   +21 more
doaj   +1 more source

Assessing Pubertal Timing, Duration, and Related Characteristics in ASXL‐Related Disorders: A Cross‐Sectional Caregiver Survey Analysis

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Limited studies have been conducted on pubertal development in populations with pre‐existing medical conditions. More than 20‐fold increased risk of early puberty has been reported in neurodevelopmental disorders; however, this is a heterogeneous group.
Amanda Piring   +4 more
wiley   +1 more source

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