Results 71 to 80 of about 64,206 (312)

Clinical Safety of Extended Interval Dosing of Nivolumab in Patients with Melanoma

Clinical Pharmacology &Therapeutics, EarlyView.
Extended interval dosing regimens of immune checkpoint inhibitors have been implemented widely. However, their approval was mainly based on pharmacokinetic modeling and simulations. Consequently, comparative safety data of extended interval dosing regimens in a real‐world setting are limited.
Ruben Malmberg, Maaike M. Hofman, Fatima Ashad, Alaa Daloul, Stefani Oosterveld, Edwin A. Basak, Esther Oomen‐de Hoop, Astrid A. M. van der Veldt, Arjen Joosse, Roelof W. F. van Leeuwen, Ron H. J. Mathijssen   +10 more
wiley   +1 more source

The effect of acute heat exposure on rat pituitary corticotroph activation: the role of vasopressin.

Folia Histochemica et Cytobiologica, 2010
The increased ambient temperature affects the function of hypothalamic-pituitary-adrenal (HPA) axis. Since thecorrelation among vasopressin (VP), adrenocorticotropic hormone (ACTH) and corticosterone (CORT) responses to variousstressors have been long ...
Nebojsa Jasnic
doaj  

Progress in the Pathogenesis, Diagnosis, and Treatment of TSH-Secreting Pituitary Neuroendocrine Tumor

Frontiers in Endocrinology, 2020
TSH-secreting pituitary neuroendocrine tumor (PitNET) is one of the causes of central hyperthyroidism. The incidence of TSH PitNET is far lower than that of other PitNETs.
Peiqiong Luo, Lin Zhang, Lidan Yang, Zhenmei An, Huiwen Tan   +4 more
doaj   +1 more source

Influence of mirtazapine on salivary cortisol in depressed patients [PDF]

, 2003
Unlike other antidepressants, mirtazapine does not inhibit the reuptake of norepinephrine or serotonin but acts as an antagonist at presynaptic alpha(2)-receptors, at postsynaptic 5-HT2 and 5-HT3 receptors, and at histaminergic H1 receptors. Furthermore,
Baghai, Thomas C., Hennig, J., Laakmann, G., Schule, C.   +3 more
core   +1 more source

Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby

Developmental Dynamics, EarlyView.
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe, Yu Chen, Geoff Shaw, Marilyn B. Renfree   +3 more
wiley   +1 more source

Estrous behavior in dairy cows: identification of underlying mechanisms and gene functions [PDF]

, 2010
Selection in dairy cattle for a higher milk yield has coincided with declined fertility. One of the factors is reduced expression of estrous behavior. Changes in systems that regulate the estrous behavior could be manifested by altered gene expression ...
Beerda, B., Boer, H.M.T., Veerkamp, R.F., Woelders, H.   +3 more
core   +2 more sources

Oxytocin Effects on Food Stimulus Processing and Food Intake in Females With or Without Binge Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Binge eating disorder (BED) is maintained by increased food‐related incentive salience, which is reflected by an attentional bias for food. Oxytocin acutely attenuates this bias in patients with anorexia nervosa and reduces food intake in males with normal or increased body weight.
Julia Nannt, Mechteld M. van den Hoek Ostende, Brunna Tuschen‐Caffier, Markus Heinrichs, Daniel Sippel, Manfred Hallschmid, Jennifer Svaldi   +6 more
wiley   +1 more source

Evaluation of anterior pituitary hormone levels in patients with atrial fibrillation

Northwestern Medical Journal
Aim: The risk of ischemic stroke is increased 5-fold in patients with atrial fibrillation (the most common reason for cardiac arrhythmia). The aim is to investigate whether insufficiency in anterior pituitary hormones develops in patients diagnosed with ...
Reyhan Köse Çobanoğlu, Derun Taner Ertuğrul, Bünyamin Yavuz, Esin Beyan   +3 more
doaj   +1 more source

Studies Using Anterior Pituitary Hormones as Antigens.

Experimental Biology and Medicine, 1959
SummaryEvidence is presented for antigenicity of TSH, ACTH, and growth hormone. Rabbit antisera to these hormones were prepared and then tested by means of a hemagglutination test in which antigen is coupled to red blood cells, by means of bisdiazotized benzidine. The antibodies to TSH showed extensive cross reactions with other pituitary hormones. The
J, FISHMAN, E E, McGARRY, J C, BECK
openaire   +2 more sources

Ligula intestinalis (Cestoda: Pseudophyllidea): an ideal fish-metazoan parasite model? [PDF]

, 2010
Since its use as a model to study metazoan parasite culture and in vitro development, the plerocercoid of the tapeworm, Ligula intestinalis, has served as a useful scientific tool to study a range of biological factors, particularly within its fish ...
Carter, V, Dufour, S, Hoole, D
core   +1 more source