Results 141 to 150 of about 66,700 (309)

Comparative Analysis of the Incidence, Prevalence, and Survival of 8 Types of Parkinsonism in a Population‐Based Study with 367 Million Person Years of Observation over 21 Years

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Findings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare. Objectives To analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug‐induced parkinsonism ...
Sacha E. Gandhi   +7 more
wiley   +1 more source

Application of Genetic Engineering Technologies for the Study of Pituitary Development and Neoplasms

open access: bronze, 2003
R. Yoshiyuki Osamura   +6 more
openalex   +2 more sources

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Alpinia galanga Rhizome Extract Shields Against Noise‐Induced Cardiotoxicity via Antioxidant and Anti‐Inflammatory Actions: Experimental Insights

open access: yesMolecular Nutrition &Food Research, EarlyView.
Alpinia galanga rhizome extract (GRE) was analyzed in vitro to identify its bioactive compounds, tested in vivo in a Wistar rat model of noise‐induced cardiotoxicity, and validated in silico by molecular docking. The combined results highlight the cardioprotective potential of GRE.
Takoua Ben Attia   +9 more
wiley   +1 more source

Disparities in Growth Hormone Deficiency Screening, Evaluation, Diagnosis, and Treatment Among At‐Risk Childhood Cancer Survivors in the US

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Minoritized childhood cancer survivors (CCS) may encounter barriers to timely late effects surveillance. We aimed to evaluate clinical and demographic differences in the likelihood of, and timing to, growth hormone deficiency (GHD) screening, evaluation, diagnosis, and treatment among at‐risk CCS treated with radiation therapy (RT).
Fulfilled Ighalo   +7 more
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

open access: yesPediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu   +4 more
wiley   +1 more source

Pituitary Neoplasm Nomenclature Workshop: Does Adenoma Stand the Test of Time? [PDF]

open access: gold, 2021
Ken K. Y. Ho   +47 more
openalex   +1 more source

Clinical perspectives and comparisons between immunoglobulin G4‐related disease and antineutrophil cytoplasmic antibody‐associated vasculitis

open access: yesRheumatology &Autoimmunity, EarlyView.
Clinical perspectives and comparisons between immunoglobulin G4‐related disease and antineutrophil cytoplasmic antibody‐associated vasculitis. Abstract Both immunoglobulin (Ig) G4‐related disease (IgG4‐RD) and antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV) are systemic disorders that affect a wide range of organs.
Wenhuan Zeng, Mingxin Bai, Yanying Liu
wiley   +1 more source

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