Results 251 to 260 of about 322,068 (275)
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Journal of Chemical & Engineering Data, 1976
Aryl amines are approximately six orders of magnitude less basic than aliphatic amines. This decrease in basicity is attributed to both resonance and inductive effects. Van der Krogt and Wepster (9, 7 1) have measured the basicities of quinuclidine (l), benzoquinuclidine (2), and dibenzoquinuclidine (3) (pKa's 10.58, 7.79, and 4.46, respectively, at ...
Dennis J. Kreil, Vernon R. Sandel
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Aryl amines are approximately six orders of magnitude less basic than aliphatic amines. This decrease in basicity is attributed to both resonance and inductive effects. Van der Krogt and Wepster (9, 7 1) have measured the basicities of quinuclidine (l), benzoquinuclidine (2), and dibenzoquinuclidine (3) (pKa's 10.58, 7.79, and 4.46, respectively, at ...
Dennis J. Kreil, Vernon R. Sandel
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Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2005
The catalytic and regulatory subunits of cAMP-dependent protein kinase (PKA) are highly dynamic signaling proteins. In its dissociated state the catalytic subunit opens and closes as it moves through its catalytic cycle. In this subunit, the core that is shared by all members of the protein kinase family is flanked by N- and C-terminal segments.
Susan S, Taylor +6 more
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The catalytic and regulatory subunits of cAMP-dependent protein kinase (PKA) are highly dynamic signaling proteins. In its dissociated state the catalytic subunit opens and closes as it moves through its catalytic cycle. In this subunit, the core that is shared by all members of the protein kinase family is flanked by N- and C-terminal segments.
Susan S, Taylor +6 more
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Mitochondrial PKA mediates sperm motility
Biochimica et Biophysica Acta (BBA) - General Subjects, 2014Mitochondria are the major source of ATP to power sperm motility. Phosphorylation of mitochondrial proteins has been proposed as a major regulatory mechanism for mitochondrial bioenergetics.Sperm motility was measured by a computer-assisted analyzer, protein detection by western blotting, membrane potential by tetramethylrhodamine, cellular ATP by ...
Rashel, Mizrahi, Haim, Breitbart
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Standardization of prekallikrein activator (PKA): the 1st British Reference Preparation for PKA
British Journal of Haematology, 1982Summary. A collaborative study on prekallikrein activator (PKA) has been carried out involving four laboratories for the purpose of establishing a British reference preparation for PKA. Samples of two plasma protein fractions (PPF) were assayed against participants’own supplies of the Bureau of Biologics Reference Preparation No. 2 (BoB 2).
P J, Kerry +3 more
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A Structural Comparison of Inhibitor Binding to PKB, PKA and PKA-PKB Chimera
Journal of Molecular Biology, 2007Although the crystal structure of the anti-cancer target protein kinase B (PKBbeta/Akt-2) has been useful in guiding inhibitor design, the closely related kinase PKA has generally been used as a structural mimic due to its facile crystallization with a range of ligands.
Thomas G, Davies +11 more
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Science Signaling, 2012
Inhibiting protein kinase A in locusts attenuates the acquisition of gregarious behavior, which is required for swarming.
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Inhibiting protein kinase A in locusts attenuates the acquisition of gregarious behavior, which is required for swarming.
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