Results 171 to 180 of about 97,124 (258)

A biomimetic microphysiological system predicts the impact of sepsis therapeutics on neutrophil-endothelial dynamics.

Lab Chip
Liu D, Esmalian Afyouni N, Yang Q, Kallogjerovic S, Gligorijevic B, Kunapuli S, Kilpatrick LE, Kiani MF.   +7 more
europepmc   +1 more source

Post-translational modifications of na+/K+-atpase subunits: regulatory mechanisms and functional implications. [PDF]

Front Cell Dev Biol
Tong J, Qin L, Zhang Y, Liu W, Liu J, Lu C.   +5 more
europepmc   +1 more source

Longitudinal untargeted metabolomics of cognitive impairment in Parkinson's disease

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Cognitive impairment is a common non‐motor symptom of Parkinson's disease (PD), yet the mechanism remains unclear. METHODS Longitudinal serum samples from PD patients in a community‐based case–control study were profiled, with cognition assessed by the Mini‐Mental State Examination at baseline and follow‐up.
Yuyuan Lin, Yu Yu, Keren Zhang, Irish Del Rosario, Aline Duarte Folle, Elizabeth Rose Mayeda, Dean P. Jones, Douglas I. Walker, Jeff Bronstein, Adrienne M. Keener, Kimberly C. Paul, Beate Ritz   +11 more
wiley   +1 more source

Advances in Understanding Calcium Sensitization in Gastrointestinal Smooth Muscles: Pathways, Interstitial Cells, and Disease. [PDF]

J Neurogastroenterol Motil
Perrino BA, Lee JY, Koh SD.
europepmc   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3333-3353, October 2026.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source

Adenosine A2A Receptor Contributes to Bidirectional Remodeling of Microglial Inflammatory Responses During Methamphetamine Exposure. [PDF]

Int J Mol Sci
Hou Z, Zhang X, Yang G, Shen B, Dong W, Jing D, Hong S, Li L.   +7 more
europepmc   +1 more source

Integrated Phytochemical, Immunological, and Network Pharmacology Investigation of Anti‐Inflammatory Lignans From Zanthoxylum armatum Fruits

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Bioassay‐guided fractionation of Zanthoxylum armatum fruits identifies three bioactive lignans—sesamin, fargesin, and eudesmin. The identified lignans attenuate CpG‐induced dendritic‐cell activation by reducing IL‐12 expression and CD80. Network pharmacology and molecular docking suggest involvement of multiple inflammatory signalling pathways ...
Ningthoujam Indrajit Singh, Salam Pradeep Singh, Chayan Mukherjee, Chingakham Brajakishor Singh   +3 more
wiley   +1 more source

Acute Ethanol Exposure Inhibits GABA Uptake in Embryonic Chicken Retina. [PDF]

Neurochem Res
Damascena ACO, Abramov AK, Pinheiro L, Dos Santos Pereira M, Trindade P, Stipursky J, De Melo Reis RA, Kubrusly RCC.   +7 more
europepmc   +1 more source

Recent Advances in Research on SHP Family Phosphatases: Signal Regulation Mechanisms and Disease Associations

Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT The protein tyrosine phosphatase family comprises a large number of members. Among them, Src homology 2 (SH2) domain‐containing protein tyrosine phosphatases (commonly referred to as the SHP family). Members of the SHP family regulate multiple signaling pathways by catalyzing the dephosphorylation of substrate proteins, thereby participating ...
Xuebin Li, Xiaoqing Duan, Nanxiu Liu, Wangjie Tang, Yi He, Dongsheng Zhou, Jianguo Yan, Yali Zhou   +7 more
wiley   +1 more source

Characterization of calcium sources and downstream signaling pathways following electrical field stimulation of rodent longitudinal esophageal muscle. [PDF]

Front Physiol
Gräfe M, Kriese JN, Kirschstein T, Köhling R, Bock F, Schulze F, Hildebrandt G, Frerker B.   +7 more
europepmc   +1 more source