Results 181 to 190 of about 97,124 (258)

Patterns of Proliferation in the Pacific Hagfish (Eptatretus stoutii) Retina Suggest an Ancient Origin for Adult Neurogenesis

Journal of Comparative Neurology, Volume 534, Issue 10, October 2026.
The hagfish, a jawless early‐branching vertebrate, has very rudimentary eyes that are diminutive and oddly devoid of melanin pigment. Yet, the degenerate hagfish eye grows throughout life and expresses canonical genes of vertebrate retinal development. ABSTRACT Comparative morphology has revealed fascinating structural and organizational differences in
Sarah N. Bradshaw, William T. Allison
wiley   +1 more source

Differential Regulation of Granule Release in Platelets and Immune Cells. [PDF]

TH Open
Xia Q, Hu J, Sun H, Zhu Z, Jiang W.
europepmc   +1 more source

METTL3 Increases Temozolomide Resistance in MGMT‐Negative Glioblastoma by Enhancing CBX5 mRNA Stability in an m6A‐IGF2BP2‐Dependent Manner

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
METTL3‐dependent m6A modification and IGF2BP2‐associated CBX5 mRNA stabilization help maintain CBX5 expression in MGMT‐negative glioblastoma. During temozolomide (TMZ) treatment, CBX5 contributes to ATM–RAD51‐associated signaling, limits persistent DNA damage and apoptosis, and thereby supports cell survival and TMZ resistance.
Hui Deng, Ruoyu Chen, Daohong Qu, Cifu Qu, Jia Shi   +4 more
wiley   +1 more source

Bioprocessing of mixed oil palm by-products with single and consortium white-rot fungi: Effects on nutritional quality, in vitro rumen fermentation, methane production, and rumen microbial populations. [PDF]

Vet World
Fhonna FA, Jayanegara A, Wajizah S, Samsudin AA, Samadi S.   +4 more
europepmc   +1 more source

Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha, Richa Gill, Sergio Crovella, Haissam Abou‐Saleh, Sahar Isa Da'as   +4 more
wiley   +1 more source

Maternal Diglyceride Diet Attenuates Selected Metabolic Effects of Maternal High‐Fat Feeding in Offspring via Energy Metabolism and Microbiota Modulation

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Maternal consumption of diacylglycerol (DAG) oil attenuates high‐fat diet (HFD)‐induced obesity and dyslipidemia in mother mice and their male offspring. DAG restored purine/pyrimidine metabolism, maintained mitochondrial morphology, suppressed the DAG‐PKCβ/PKD1‐NF‐κB pathway, and promoted fatty acid oxidation (CPT1A↑, ACSS2↓).
Qiu Wu, Chun Li, Shihao Song, Hanyue Wang, Rentang Zhao, Luyan Sun, Bingqing Shang, Yue Geng   +7 more
wiley   +1 more source

Combined Effects of Vitamin D3 and Extracorporeal Shockwave Therapy on Osteoblast Differentiation via F-actin mediated Pdia3 Membrane Localization. [PDF]

Int J Med Sci
Cheng JH, Hsu CH, Tsai ML, Chen JW, Jhan SW, Lee S, Huang CY, Hsu SL.   +7 more
europepmc   +1 more source

Quercetin in Myocardial Ischemia–Reperfusion Injury: Mechanistic Evidence, Cardioprotective Effects, and Translational Challenges

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
Quercetin mitigates myocardial ischemia–reperfusion injury through coordinated antioxidant, anti‐inflammatory, and anti‐apoptotic mechanisms, leading to reduced infarct size and improved cardiac function. Its multi‐target cardioprotective effects highlight quercetin as a promising therapeutic candidate for ischemic heart disease.
Rony Abdi Syahputra, Princella Halim, Sasniwiati Sari Hasibuan, Adhayani Lubis   +3 more
wiley   +1 more source

Targeted lipidomics between hPheo1 and SDHB KD cells reveal changes in bioactive lipids and PKC with polyamine pathway inhibition. [PDF]

Physiol Rep
Alli AA, Bala N, Xu Y, Denslow ND, Ghayee HK.   +4 more
europepmc   +1 more source

Shear Stress‐Stimulated Trafficking of Endothelial Piezo1 to Splenic Capsule Boosts Spleen Contraction and Exercise Endurance

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
The vasculo‐splenic axis during exercise: shear stress triggers the release of medium/large extracellular vesicles from vascular endothelial cells via activation of Piezo1, shuttling Piezo1 to the smooth muscle cells in the splenic capsule; the translocated Piezo1 within the splenic capsule acts as a downstream effector of the α1‐adrenergic receptor ...
Jing Lou, Mingzong Yang, Yang Hu, Xuyun Liu, Han Li, Zihang Feng, Yuxin Xi, Changyang Xing, Lijun Yuan, Jia Li, Shengpeng Wang, Feng Gao, Xing Zhang   +12 more
wiley   +1 more source