Results 101 to 110 of about 60,739 (253)
On Using Encryption Techniques to Enhance Sticky Policies Enforcement [PDF]
, 2008 How to enforce privacy policies to protect sensitive personal data has become an urgent research topic for security researchers, as very little has been done in this field apart from some ad hoc research efforts.
Tang, Qiang
core +3 more sources
Default Effect in ESG Investment: When a Recommendation Goes a Long Way
Business Strategy and the Environment, EarlyView.ABSTRACT Individual investors display a positive attitude toward ESG investments but typically fail to act upon it. We report results from a preregistered online experiment testing a default option on 1050 US investors examining the mechanisms driving the effectiveness of default options in promoting ESG investments.
Sai Sravanthi Ramadugula +2 more
wiley +1 more source
On Unit Groups of Completely Primary Finite Rings [PDF]
, 2008 Let R be a commutative completely primary finite ring with the unique maximal ideal J such that J3 = (0) and J2 ≠ (0): Then R⁄J ≅ GF(pr) and the characteristic of R is pk, where 1 ≤ k ≤ 3, for some prime p and positive ...
Chikunji, Chiteng'a John
core +1 more source
Cell & Bioscience, 2023 Background Activation of RNA-dependent stress kinase PKR, especially by viral double-stranded RNA, induces eukaryotic initiation factor 2 α-chain (eIF2α) phosphorylation, attenuating thereby translation.
Lise Sarah Namer +5 more
doaj +1 more source
The Leader Protein of Theiler's Virus Prevents the Activation of PKR
Journal of Virology, 2019 The leader (L) protein encoded by cardioviruses is a very short multifunctional protein that contributes to evasion of the host innate immune response. This protein notably prevents the formation of stress granules in infected cells.
F. Borghese +3 more
semanticscholar +1 more source
RNA Dimerization Promotes PKR Dimerization and Activation [PDF]
Journal of Molecular Biology, 2009 The double-stranded RNA (dsRNA)-activated protein kinase [protein kinase R (PKR)] plays a major role in the innate immune response in humans. PKR binds dsRNA non-sequence specifically and requires a minimum of 15-bp dsRNA for one protein to bind and 30-bp dsRNA to induce protein dimerization and activation by autophosphorylation.
Laurie A, Heinicke +7 more
openaire +2 more sources
iNew Medicine, EarlyView.This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng +3 more
wiley +1 more source
RNA BiologyProtein kinase R (PKR) is a serine/threonine kinase that recognizes double-stranded RNAs (dsRNAs) to initiate innate immune signalling during viral infection. PKR dimerizes on long dsRNAs and undergoes autophosphorylation.
Jiyoon Chung +3 more
doaj +1 more source
PKR's protective role in viral myocarditis
Virology, 2003 Reovirus-induced murine myocarditis provides an excellent model for the human disease. Previously, we showed that reovirus induction of and sensitivity to interferon-beta (IFN-beta) are important determinants of protection against cardiac damage. IFN-beta induces a number of genes with antiviral activities, including the dsRNA-activated protein kinase,
Stewart, Michael J +2 more
openaire +2 more sources
Biochemical Analysis of PKR Activation by PACT [PDF]
Biochemistry, 2009 Many extracellular stresses cause inhibition of translation initiation by triggering phosphorylation of the initiation factor, eIF-2alpha. A major protein kinase responsible for this phosphorylation is PKR, a latent kinase which itself needs to be activated by autophosphorylation.
Gregory A, Peters +2 more
openaire +2 more sources