Results 81 to 90 of about 1,501,016 (387)
Arthritis Care &Research, EarlyView.Objective Patients with knee osteoarthritis rely on symptomatic treatments, in which up to 75% of the pain reduction can be attributed to the placebo effect. This effect may vary based on treatment type (eg, biologics vs nonbiologic injection) and route of administration (eg, intra‐articular vs topical vs oral).
Johanna M. Borst +5 more
wiley +1 more source
Randomised controlled trial of homoeopathy versus placebo in perennial allergic rhinitis with overview of four trial series [PDF]
, 2000 OBJECTIVE: To test the hypothesis that homoeopathy is a placebo by examining its effect in patients with allergic rhinitis and so contest the evidence from three previous trials in this series.
Aitchison, T, +4 more
core +2 more sources
Metabolic Consequences of Rheumatoid Arthritis
Arthritis Care &Research, EarlyView.Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry +2 more
wiley +1 more source
Measurement of event-related potentials and placebo [PDF]
Serbian Journal of Electrical Engineering, 2014 ERP is common abbreviation for event-related brain potentials, which are measured and used in clinical practice as well as in research practice. Contemporary studies of placebo effect are often based on functional neuromagnetic resonance (fMRI),
Sovilj Platon +4 more
doaj +1 more source
Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney [PDF]
, 2015 BACKGROUND: The role of cyclooxygenase(COX)-1 and COX-2 in the saluretic and renin-angiotensin responses to loop diuretics in the cat is unknown. We propose in vivo characterisation of isoform roles in a furosemide model by administering non-steroidal ...
A Hayes +42 more
core +2 more sources
Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus
Psychotherapy and Psychosomatics, 2018 Background: Placebo and nocebo effects occur in clinical or laboratory medical contexts after administration of an inert treatment or as part of active treatments and are due to psychobiological mechanisms such as expectancies of the patient. Placebo and
A. Evers +29 more
semanticscholar +1 more source
Arthritis Care &Research, EarlyView.Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun +8 more
wiley +1 more source
Southern African Journal of Infectious Diseases, 2016 Randomisation is an integral component of any sensible clinical trial. Randomisation is the only way we can be sure that the patients have been allocated into the treatment arms with as minimum bias as possible, and that the treatment arms are similar ...
Jesca M. Batidzirai
doaj +1 more source
Frontiers in Pharmacology, 2021 Background: The successful application of randomized, double-blind placebo-controlled studies requires maximum blinding. Organoleptic properties of the placebo should be similar to the drug, making it difficult to distinguish between the two.
Mengli Xiao +12 more
doaj +1 more source
Fish oil (n-3 fatty acids) in drug resistant epilepsy: a randomised placebo-controlled crossover study. [PDF]
, 2014 Backgroundn-3 fatty acids inhibit neuronal excitability and reduce seizures in animal models. High-dose fish oil has been explored in two randomised trials in drug resistant epilepsy with negative results.
DeGiorgio, Christopher M +6 more
core +1 more source