Results 111 to 120 of about 5,277,200 (190)
Regulation of Vertebrate Planar Cell Polarity [PDF]
, 2010 Planar cell polarity (PCP) provides positional information to a field of cells, coordinating the orientation of polarized structures or the direction of polarized cell movements.
Trinh, Jason
core +2 more sources
Biology Open, 2014 Planar cell polarity (PCP) signaling plays a critical role in tissue morphogenesis. In mammals, disruption of three of the six “core PCP” components results in polarity-dependent defects with rotated cochlear hair cell stereocilia and open neural tube ...
Chunqiao Liu +5 more
doaj +1 more source
StructurePlanar cell polarity (PCP), essential to multicellular developmental processes, arises when cells polarize and align across tissues. Central to PCP is CELSR1, an atypical cadherin featuring a long ectodomain with nine extracellular cadherin (EC) repeats,
E. Tamilselvan, Marcos Sotomayor
semanticscholar +1 more source
A New Spin on Planar Cell Polarity [PDF]
, 2010 The generation of planar cell polarity (PCP) and tissue shape during morphogenesis is tightly linked, but it is not clear how. Aigouy et al. (2010) now show in the developing Drosophila wing that PCP initially has a radial orientation that becomes ...
Patricio Olguin +3 more
core +1 more source
Planar cell polarity and the kidney. [PDF]
, 2013 Planar cell polarity (PCP) is the uniform orientation and alignment of a group of cells orthogonal to the apical-basal axis within a tissue. Originally described in insects, it is now known that PCP is required for many processes in vertebrates ...
Papakrivopoulou, E +3 more
core +1 more source
Regions within a single epidermal cell of Drosophila can be planar polarised independently
eLife, 2015 Planar cell polarity (PCP), the coordinated and consistent orientation of cells in the plane of epithelial sheets, is a fundamental and conserved property of animals and plants.
Miguel Rovira +3 more
doaj +1 more source
Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
PTK7-Src Signaling at Epithelial Cell Contacts Mediates Spatial Organization of Actomyosin and Planar Cell Polarity [PDF]
, 2014 SummaryActomyosin contractility plays a key role in tissue morphogenesis. During mammalian development, PTK7 regulates epithelial morphogenesis and planar cell polarity (PCP) through modulation of actomyosin contractility, but the underlying mechanism is
Lu, Xiaowei +5 more
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Roles of planar cell polarity pathways in the development of neutral tube defects
Journal of Biomedical Science, 2011 Neural tube defects (NTDs) are the second most common birth defect in humans. Despite many advances in the understanding of NTDs and the identification of many genes related to NTDs, the fundamental etiology for the majority of cases of NTDs remains ...
Hua Yimin +3 more
doaj +1 more source
Ubiquitin Connects with Planar Cell Polarity [PDF]
, 2009 Planar cell polarity (PCP) regulates the orientation of cells in epithelia and of mesenchymal cells during gastrulation. In this issue, Narimatsu et al. (2009) report that the Smurf E3 ubiquitin ligases are required for localized protein degradation of a
Mlodzik, Marek
core +1 more source