Results 171 to 180 of about 24,770,947 (300)

An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

open access: yesAdvanced Science, EarlyView.
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang   +8 more
wiley   +1 more source

Single‐Cell Profiling Identifies SLC2A5‐Mediated Fructose Metabolism as a Vulnerability in Primary CNS Lymphoma

open access: yesAdvanced Science, EarlyView.
Glucose deprivation in the primary CNS lymphoma (PCNSL) tumor microenvironment drives SLC2A5 (encoding GLUT5)‐dependent fructose metabolism in tumor cells, while hypoxia induces HIF‐mediated SLC2A5 expression in tumor‐supportive macrophages, revealing SLC2A5‐driven fructose utilization as a shared and targetable metabolic vulnerability across malignant
Qiaoli Wu   +13 more
wiley   +1 more source

Targeted Delivery of Indole‐3‐Pyruvic Acid Suppresses Macrophage Ferroptosis to Enhance CD8+ T Cell‐Mediated Immunotherapy Response in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
A microbiota‐derived metabolite, indole‐3‐pyruvic acid, suppresses macrophage ferroptosis through the AHR–NF‐κB–SLC7A11 axis. This preserves CD8+ T cell function in bladder cancer. Macrophage‐targeted nanoparticles enhance indole‐3‐pyruvic acid delivery and overcome resistance to PD‐1 blockade.
Jianwen Lao   +15 more
wiley   +1 more source

Optimizing Plant-Based Diet Using Goal Programming

open access: yes, 2016
Tato bakalářská práce se zabývá využitím lineárního a cílového programování k sestavení jídelníčku z rostlinné stravy. V první kapitole je popsána teorie lineárního programování a nutričního problému, dále teorie vícekriteriálního rozhodování a cílového ...
Štěpánková, Karolína
core  

The influence of a plant-based diet on the composition and functions of the human gut microbiota: a review. [PDF]

open access: yesFront Nutr
Egas-Montenegro E   +4 more
europepmc   +1 more source

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

open access: yesAdvanced Science, EarlyView.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang   +11 more
wiley   +1 more source

Comparative analysis of dietary intake between vegetarian and omnivorous strength training practitioners: Protein consumption disparity

open access: yesRevista Brasileira de Nutrição Esportiva
The interaction between a vegetarian diet and strength training remains an area lacking substantial information. However, it is recognized that both vegetarian and omnivorous practitioners require adequate energy and nutrient intake to optimize ...
Randerson André Fernandes de Souza   +4 more
doaj  

Barriers and facilitators for consuming a plant-based diet in patients with knee osteoarthritis: a qualitative study. [PDF]

open access: yesFront Nutr
Chmelar S   +8 more
europepmc   +1 more source

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