Results 91 to 100 of about 6,450,626 (234)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Plant-derived extracellular vesicles: an alternative and complementary therapeutic approach for genitourinary tumors

Frontiers in Cell and Developmental Biology
Over the past four decades, the incidence of genitourinary tumors has risen significantly, becoming a major global health concern. This trend necessitates the exploration of more effective treatment strategies.
Yuqing Huang, Yunmeng Zhang, Kecheng Lou, Shangzhi Feng, Guoqiang Feng   +4 more
doaj   +1 more source

Supplementary information files for Cell culture-derived extracellular vesicles: Considerations for reporting cell culturing parameters

, 2023
Supplementary files for article Cell culture-derived extracellular vesicles: Considerations for reporting cell culturing parametersCell culture‐conditioned medium (CCM) is a valuable source of extracellular vesicles (EVs) for basic scientific ...
Faisal J Alibhai (17275761), Ana Claudia Torrecilhas (360126), Carlos Salomon (3164337), Stefania Bruno (244994), Mario Gimona (244407), Francesca Perut (6387281), Lorena Martin‐Jaular (17261149), Hossein Baharvand (157456), Rienk Nieuwland (293501), Carolina Soekmadji (158668), Suresh Mathivanan (14706238), Ghasem Hosseini Salekdeh (9230912), Inge Nelissen (103899), Verena Börger (9753098), Faezeh Shekari (5782067), Owen Davies (1253895), Gabriella Pocsfalvi (564718), Bernd Giebel (255529), Tobias Tertel (4326100), Esther Nolte‐’t Hoen (17275772), Simon Staubach (2118262), Stefano Pluchino (249826), Ganesh Vilas Shelke (17275777), Kenneth Witwer (3448757), Lorraine O'Driscoll (328515), Dandan Zhu (513418), Clotilde Théry (177438)   +26 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles in SARS-CoV-2 and H1N1 influenza-induced acute lung injury

Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) have shown anti-inflammatory potential in multiple inflammatory diseases. In the March 2022 issue of the Journal of Extracellular Vesicles, it was shown that EVs from human MSCs can ...
Lötvall, Jan,, Cho, Byong Seung, Lee, Jun Ho, Jeon, Hyungtaek   +3 more
core   +1 more source

Impacting the gut microbiome through dietary plant-based extracellular vesicles [PDF]

ExRNA
Plant-based diets promote greater diversity and even distribution of gut microbiota which is beneficial to intestinal health, yet dietary complexity has hampered the ability to establish how specific components within a diet alter microbiome structure ...
Hormat Rhein, Ardawna J. Green, Jian Yang, Melinda A. Engevik, Angela V. Serrano, Jessica K. Runge, Ruth Ann Luna, Sana Sharif, Xinli Liu, Kendal Hirschi, Jennifer K. Spinler   +10 more
doaj   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

P10 | BIOLOGICAL ACTIVITIES OF CITRUS LIMON-, VITIS VINIFERA- AND ACTINIDIA DELICIOSA-DERIVED EXTRACELLULAR VESICLES ON HUMAN CACO-2 CELLS

European Journal of Histochemistry
Extracellular vesicles (EVs) are nano-sized, membrane-enclosed particles naturally released by all living cells as a conserved mechanism of intercellular communication.
GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
doaj   +1 more source

Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy

, 2021
Bacterial outer membrane vesicles (OMV) have gained attention as a promising new cancer vaccine platform for efficiently provoking immune responses. However, OMV induce severe toxicity by activating the innate immune system.
Lötvall, Jan,, Svennerholm, Kristina,, Jan Lötvall, Crescitelli, Rossella,, Lässer, Cecilia,, Inta Gribonika, Rossella Crescitelli, Kristina Svennerholm, Kyong‐Su Park, Park, Kyong-Su,, Gribonika, Inta,, Cecilia Lässer   +11 more
core   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source