Results 81 to 90 of about 2,543,561 (297)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Microsurgery for Male Infertility

, 2020
About one in six men with infertility has azoospermia, defined as the complete absence of sperm in the ejaculate. Obstructive azoospermia is an important diagnostic category since a number of these cases can be treated surgically.
Kumar, Manoj, Manoj Kumar, Kumar, Rajeev, Rajeev Kumar   +3 more
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Sexual reproduction in plants under high temperature and drought stress

Cell Reports
Summary: Climate-change-induced extreme heat and drought increasingly threaten plant growth and development, with a particularly significant impact on sexual reproduction.
Dong Qian, Muxuan Wang, Yue Niu, Yang Yang, Yun Xiang   +4 more
doaj   +1 more source

In vivo and in silico investigation of effects of ethanol extract of moringa oleifera leaves on female fertility, using fruit flies and molecular docking [PDF]

Journal of Clinical and Basic Research, 2023
Background: Infertility is an important issue for couples that may cause various psychological and emotional problems. Female infertility disorders play a major role in approximately 50-80% of the causes of infertility in various areas in Nigeria ...
Ben Ehigiator, Uchechukwu Loveth Iyanyi, Kelechi Samuel Mobisson, Onuchukwu Ukata   +3 more
doaj  

Utilization of Infertility Treatments: The Effects of Insurance Mandates [PDF]

Over the last several decades, both delay of childbearing and fertility problems have become increasingly common among women in developed countries. At the same time, technological changes have made many more options available to individuals experiencing
Lucie Schmidt, Marianne P. Bitler
core  

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Salivary protein NlSP6935 that restricted to rice planthoppers is critical for insect survival and host defense regulation

Journal of Integrative Agriculture
Saliva plays a crucial role in mediating plant–insect interactions, yet the functional diversity of salivary proteins remains poorly understood. Here, we identify NlSP6935, a salivary gland-specific protein conserved among rice planthoppers but absent in
Zelong Zhang, Xiaojing Wang, Xinye Xu, Tangbin Hu, Chuanxi Zhang, Haijian Huang   +5 more
doaj   +1 more source

The Efficiency of a Group-Specific Mandated Benefit Revisited: The Effect of Infertility Mandates [PDF]

This paper examines the labor market effects of state health insurance mandates that increase the cost of employing a demographically identifiable group.
Joanna N. Lahey
core  

Membrane Trafficking in Plant Immunity [PDF]

, 2017
Plants employ sophisticated mechanisms to interact with pathogenic as well as beneficial microbes. Of those, membrane trafficking is key in establishing a rapid and precise response.
Zavaliev, Raul, Raul Zavaliev, Xinnian Dong, Dong, Xinnian, Yangnan Gu, Gu, Yangnan   +5 more
core   +1 more source