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Infertility and assisted reproductive technologies in Serbia [PDF]

open access: yes, 2022
Infertility is a significant challenge, both on individual and macro levels. The overall aim of this paper is to contribute to better understanding infertility in Serbia by analysing relevant policies and programmes, data on the epidemiology of ...
Sedlecky, Katarina   +4 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Assessing fertility preservation strategies: A scoping review

open access: yesAsian Pacific Journal of Reproduction
Objective: To describe the various options available for preserving female and/or male fertility, taking into account both social and medical aspects, and to identify the effects of different natural products on male infertility extracted from plants ...
Chaimaa Hilali   +7 more
doaj   +1 more source

Protective effects of phenolic phytochemicals on male fertility: a narrative review [PDF]

open access: yesBrazilian Journal of Biology
Infertility is a global health issue and is closely related to oxidative stress, which occurs when high concentrations of free radicals surpass the protective effects of antioxidant molecules and enzymes.
J. V. Lopes-Ferreira   +4 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Future Perspectives in the Diagnosis and Management of Unexplained Male Infertility

open access: yes, 2015
Unexplained male infertility (UMI) remains a challenge to both the physician and the patient. Currently, the management options for unexplained infertility, beyond assisted reproductive techniques, are typically limited to empiric therapies. This chapter
Peter N. Schlegel   +5 more
core   +1 more source

Infertility associated with adenomyosis. Literature review

open access: yes, 2023
Background. Infertility tends to become one more modern pandemic. According to some estimates, the percentage of infertile couples varies between 10–25% (48–180 million).
Ebecha K. Barinova   +6 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Investigating Marital Relationship in Infertility: A Systematic Review of Quantitative Studies [PDF]

open access: yes, 2012
Background: Infertility is a complex issue that affects individuals and groups, and also it has serious implications for the mental and social well-being of those involved.
Coates, Rosemary   +2 more
core  

The role of hyperglycaemia, oxidative stress, and inflammation in diabetes-related male infertility: Therapeutic properties of medicinal plants [PDF]

open access: yesJournal of HerbMed Pharmacology
The prevalence of diabetes mellitus (DM) continues to rise at an alarming rate. DM leads to a decline in male reproductive function. Hyperglycaemia is an instigator of both oxidative stress and inflammation in the male reproductive system.
Murendeni Nethengwe   +3 more
doaj   +1 more source

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