Results 71 to 80 of about 208,183 (312)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Lipid-lowering Efficacy of Plant Proteins and Their Application Potential

Shipin gongye ke-ji
In recent years, there has been a gradual increase in the prevalence of obesity, hyperlipidaemia, coronary atherosclerosis, non-alcoholic fatty liver disease, and other conditions attributed to shifts in dietary patterns. These chronic ailments resulting
Yue WANG, Chunhua GUAN, Hong BI, Fengyating WU, Yanqin SHEN, Liang TAO, Yang TIAN   +6 more
doaj   +1 more source

Plant Proteins: Methods of Quality Assessment and the Human Health Benefits of Pulses

Foods, 2023
As countries increase their standard of living and individual income levels rise, there is a concomitant increase in the demand for animal-based protein. However, there are alternative sources.
Matthew G. Nosworthy, Gerardo Medina, Zhan-Hui Lu, James D. House   +3 more
doaj   +1 more source

Variation in the apparent faecal digestibility of macronutrients and urinary energy excretion for three diets varying in fat and fibre content-- assessment of the Atwater factors and related energy conversion factors : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Nutritional Science at Massey University, Palmerston North, New Zealand [PDF]

, 2007
Background: Current systems to estimate dietary metabolisable energy (ME), often based on Atwater factors, assume that diet ME can be accurately predicted based on a few chemical components and that the ME of components is constant across foods ...
Zou, Maggie Long
core  

Unique Organization of Extracellular Amylases into Amylosomes in the Resistant Starch-Utilizing Human Colonic Firmicutes Bacterium Ruminococcus bromii [PDF]

, 2015
ACKNOWLEDGMENTS We acknowledge support from BBSRC grant no. BB/L009951/1, from the Scottish government Food, Land and People program, and from the Society for Applied Microbiology. E.A.B. is supported by a grant (no.
Bayer, Edward A., Dassa, Bareket, David, Ben, Duncan, Sylvia H, Flint, Harry J, Henrissat, Bernard, Juge, Natahlie, Koropatkin, Nicole M, Laverde Gomez, Jenny, Louis, Petra Gisela Helen, Sheridan, Paul O, Ze, Xiaolei   +11 more
core   +4 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Xylo-oligosaccharides improve the adverse effects of plant-based proteins on weaned piglet health by maintaining the intestinal barrier and inhibiting harmful bacterial growth

Frontiers in Microbiology, 2023
IntroductionPiglets are more susceptible to weaning stress syndrome when fed high levels of plant-based proteins that contain abundant food antigens and anti-nutritional factors.
Qibing Wang, Yang Zhao, Lei Guo, Xiangyuan Ma, Yi Yang, Yong Zhuo, Xuemei Jiang, Lun Hua, Lianqiang Che, Shengyu Xu, Bin Feng, Zhengfeng Fang, Jian Li, Yan Lin, De Wu   +14 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Impact of Plant-Based Diets on Hepatosomatic Index, Circulating Globulins and Growth in Rainbow Trout (Oncorhynchus mykiss)

Fishes
Serum proteins are essential for maintaining osmotic pressure, regulating pH, transporting metabolites, and supporting immune responses. Studying the effects of plant-based diets on these proteins is crucial to understanding their impact on fish health ...
Alejandro Villasante, Elías Figueroa, Karina Godoy, Patricio Dantagnan, Johana López-Polo, Rafael Opazo, Jaime Romero   +6 more
doaj   +1 more source

Is There Scope for a Novel Mycelium Category of Proteins alongside Animals and Plants?

Foods, 2020
In the 21st century, we face a troubling trilemma of expanding populations, planetary and public wellbeing. Given this, shifts from animal to plant food protein are gaining momentum and are an important part of reducing carbon emissions and consumptive ...
Emma J. Derbyshire
doaj   +1 more source