Results 91 to 100 of about 198,768 (248)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A precise and high-throughput assay for stem structural characteristics deepens understanding of lodging resistance in sorghum

BMC Plant Biology
Background Plant stem structural characteristics are crucial factors determining plant lodging resistance, while high throughput methods for rapid surveys of these traits are still lacking in sorghum.
Jianguo Li, Liyan Zhao, Hongzeng Fan, Falin Zhao, Dandan He, Bo Li, Jibin Wang, Guosheng Xie, Zhen Hu, Chuchuan Fan, Lingqiang Wang   +10 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Exogenous 2,4-Epibrassinolide Alleviates Alkaline Stress in Cucumber by Modulating Photosynthetic Performance

Plants
Brassinosteroids (BRs) are recognized for their ability to enhance plant salt tolerance. While considerable research has focused on their effects under neutral salt conditions, the mechanisms through which BRs regulate photosynthesis under alkaline salt ...
Wenjing Nie, Qinghai He, Jinzhao Ma, Hongen Guo, Qinghua Shi   +4 more
doaj   +1 more source

Salicylic acid and RNA interference mediate antiviral immunity of plant stem cells. [PDF]

Proc Natl Acad Sci U S A, 2023
Incarbone M, Bradamante G, Pruckner F, Wegscheider T, Rozhon W, Nguyen V, Gutzat R, Mérai Z, Lendl T, MacFarlane S, Nodine M, Mittelsten Scheid O.   +11 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Assessment of Genetic Variability, Character Association and Path Coefficient Analysis in Gomphrena (Gomphrena globosa L.) Genotypes for Productivity and Quality Traits

International Journal of Bio-Resource and Stress Management
An experiment was conducted during November 2021–March, 2022 at the experimental block of Floriculture and Landscape Architecture, College of Horticulture, Bagalkot, Karnataka, India using thirteen different Gomphrena (Gomphrena globosa L.) genotypes ...
G. N. Nagajyothi, S. K. Balaji, D. Satish, R. P. Sateesh   +3 more
doaj   +1 more source

Reprogramming of spermatogonial stem cells into pluripotent stem cells in the spheroidal state

Animal Cells and Systems, 2019
Spermatogonial stem cells (SSCs) are unipotent adult stem cells, capable of differentiating into sperm cells. SSCs can be cultured in vitro for a long time.
Yukyeong Lee, Minseong Lee, Seung-Won Lee, Na Yong Choi, Seokbeom Ham, Hye Jeong Lee, Kisung Ko, Kinarm Ko   +7 more
doaj   +1 more source