Results 111 to 120 of about 198,768 (248)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Plant stem tissue modeling and parameter identification using metaheuristic optimization algorithms. [PDF]

Sci Rep, 2022
Ghoneim MS, Gadallah SI, Said LA, Eltawil AM, Radwan AG, Madian AH.   +5 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Plant stem cell extract from Coffea canephora shows antioxidant, anti-inflammatory, and skin regenerative properties mediated by suppression of nuclear factor-κB. [PDF]

Braz J Med Biol Res, 2023
Guidoni M, Sousa Júnior AD, Aragão VPM, E Silva MVT, Barth T, Clarindo WR, Endringer DC, Scherer R, Fronza M.   +8 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Interaction of Nitrogen Fertilizers and Plant Density on Physiological Characteristics, Yield and Yield Components of Canola (Brassica napus L.)

Ikufīziyuluzhī-i Giyāhān-i Zirā̒ī
Nitrogen fertilizer application and optimal density are important factors in increasing yield of canola. This study was carried out in order to investigate the effects of nitrogen fertilizers and plant density on some physiological characteristics, yield
Behnam Hosseininasab, Farhad Mohajeri, Mohammad Rahim Owji, Mehdi Madandoust   +3 more
doaj  

Determining the internal orientation, degree of ordering, and volume of elongated nanocavities by NMR: Application to studies of plant stem. [PDF]

J Magn Reson, 2022
Furman G, Meerovich V, Sokolovsky V, Xia Y, Salem S, Shavit T, Blumenfeld-Katzir T, Ben-Eliezer N.   +7 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Potential of Plant Stem Cells as Helpful Agents for Skin Disorders—A Narrative Review

Applied Sciences
Recently, cellular senescence has been of great interest due to its pleiotropic nature and association with both physiological (e.g., aging) and pathological conditions.
Anastasia Aliesa Hermosaningtyas, Justyna Chanaj-Kaczmarek, Małgorzata Kikowska, Justyna Gornowicz-Porowska, Anna Budzianowska, Mariola Pawlaczyk   +5 more
doaj   +1 more source

Plant stem cell research is uncovering the secrets of longevity and persistent growth. [PDF]

Plant J, 2021
Umeda M, Ikeuchi M, Ishikawa M, Ito T, Nishihama R, Kyozuka J, Torii KU, Satake A, Goshima G, Sakakibara H.   +9 more
europepmc   +1 more source