Results 21 to 30 of about 503,732 (331)

Analysis of MicroRNAs Associated With Carotid Atherosclerotic Plaque Rupture With Thrombosis

open access: yesFrontiers in Genetics, 2021
Atherosclerosis is a progressive vascular wall inflammatory disease, and the rupture of atherosclerotic vulnerable plaques is the leading cause of morbidity and mortality worldwide.
Peng Nie   +4 more
doaj   +1 more source

Association of Statin Treatment With Progression of Coronary Atherosclerotic Plaque Composition.

open access: yesJAMA cardiology, 2021
Importance The density of atherosclerotic plaque forms the basis for categorizing calcified and noncalcified morphology of plaques. Objective To assess whether alterations in plaque across a range of density measurements provide a more detailed ...
A. V. van Rosendael   +38 more
semanticscholar   +1 more source

Potential circulating biomarkers of atherosclerotic plaque vulnerability in patients in the early recovery period of atherothrombotic stroke [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2023
Despite the informative value of ultrasound examination of atherosclerotic vascular lesions, predicting­ the plaque vulnerabili­ty remains difficult. Circulating blood biomarkers could provide additional criteria that would allow better determination of ...
O. Ya. Mykhalojko, I. Ya. Mykhalojko
doaj   +1 more source

Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles

open access: yesTheranostics, 2021
Inflammation is a pivotal driver of atherosclerotic plaque progression and rupture and is a target for identifying vulnerable plaques. However, challenges arise with the current in vivo imaging modalities for differentiating vulnerable atherosclerotic ...
Wei Tong   +8 more
semanticscholar   +1 more source

The Effect of PCSK9 Inhibition on the Stabilization of Atherosclerotic Plaque Determined by Biochemical and Diagnostic Imaging Methods

open access: yesMolecules, 2023
Atherosclerosis is a multifactorial, progressive, chronic inflammatory disease. Ultrasound and magnetic resonance imaging are the most accurate predictors of atherosclerotic plaque instability (MRI).
Marcin Basiak   +7 more
doaj   +1 more source

The Applications of Single-Cell RNA Sequencing in Atherosclerotic Disease

open access: yesFrontiers in Cardiovascular Medicine, 2022
Atherosclerosis still is the primary cause of death worldwide. Our characterization of the atherosclerotic lesion is mainly rooted in definitions based on pathological descriptions.
Lotte Slenders   +5 more
doaj   +1 more source

Plasma Testosterone Levels and Atherosclerotic Plaque Gene Expression in Men With Advanced Atherosclerosis

open access: yesFrontiers in Cardiovascular Medicine, 2021
Aims: Low plasma testosterone levels have been shown to predict worse outcome in men with severe atherosclerotic disease. We hypothesized that a low plasma testosterone level affects disease risk through changes in gene expression in atherosclerotic ...
Floor Groepenhoff   +9 more
doaj   +1 more source

Macrophage death in atherosclerosis: potential role in calcification

open access: yesFrontiers in Immunology, 2023
Cell death is an important aspect of atherosclerotic plaque development. Insufficient efferocytosis of death cells by phagocytic macrophages leads to the buildup of a necrotic core that impacts stability of the plaque.
Jaap G. Neels   +2 more
doaj   +1 more source

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

open access: yesCirculation Research, 2020
Supplemental Digital Content is available in the text. Rationale: Atherosclerotic lesions are known for their cellular heterogeneity, yet the molecular complexity within the cells of human plaques has not been fully assessed. Objective: Using single-cell
M. Depuydt   +22 more
semanticscholar   +1 more source

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