Results 61 to 70 of about 1,087,535 (239)

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source

A digital photography dataset for Vaccinia Virus plaque quantification using Deep Learning

Scientific Data
Virological plaque assay is the major method of detecting and quantifying infectious viruses in research and diagnostic samples. Furthermore, viral plaque phenotypes contain information about the life cycle and spreading mechanism of the virus forming ...
Trina De, Subasini Thangamani, Adrian Urbański, Artur Yakimovich   +3 more
doaj   +1 more source

Immunoplaque Assay (Influenza Virus)

Bio-Protocol, 2013
Despite developed long time ago, plaque assay is still the gold standard for viral titer quantification in modern virology. The standard crystal violet-based plaque assay relies on virus’ ability to induce cytopathic effect (CPE) which limits the assay ...
Victor Tse, Yueting Zhang, Gary Whittaker   +2 more
doaj   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Elimination of Mycoplasma contamination in Chlamydia stocks as a result of in vivo passage or plaque isolation

BMC Research Notes, 2018
Objective This study aims to eliminate Mycoplasma spp. contamination from laboratory stocks of Chlamydia spp. by in vivo passage or by plaque assay. Results We have described two methods of eliminating Mycoplasma contamination from Chlamydia laboratory ...
Ira M. Sigar, Justin H. Schripsema, Kathleen A. Kelly, Ashlesh K. Murthy, Srikanth Manam, Kyle H. Ramsey   +5 more
doaj   +1 more source

Propagation, Inactivation, and Safety Testing of SARS-CoV-2

Viruses, 2020
In late 2019, a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, the capital of the Chinese province Hubei.
Alexander S. Jureka, Jesus A. Silvas, Christopher F. Basler   +2 more
doaj   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Human Antibodies to VP4 Inhibit Replication of Enteroviruses Across Subgenotypes and Serotypes, and Enhance Host Innate Immunity

Frontiers in Microbiology, 2020
Hand, foot, and mouth disease (HFMD) is a highly contagious disease that usually affects infants and young children (<5 years). HFMD outbreaks occur frequently in the Asia-Pacific region, and these outbreaks are associated with enormous healthcare and
Siratcha Phanthong, Siratcha Phanthong, Jaslan Densumite, Jaslan Densumite, Watee Seesuay, Jeeraphong Thanongsaksrikul, Salma Teimoori, Nitat Sookrung, Nitat Sookrung, Yong Poovorawan, Napa Onvimala, Ratigorn Guntapong, Kovit Pattanapanyasat, Wanpen Chaicumpa   +13 more
doaj   +1 more source

Travelling to Rome : inflammation, endoplasmic reticulum stress and angiogenesis during atherosclerotic plaque development [PDF]

, 2010
Cardiovascular diseases are the leading cause of death worldwide followed by cancer. Atherosclerosis, the major underlying cause of cardiovascular diseases, is a syndrome affecting medium-sized and large arteries.
Kyriakakis, Emmanouil
core   +1 more source