Fage Litik Spesifik Escherichia coli pada Limbah Cair Pasar Tradisional di Kota Banda Aceh
Changes in environmental conditions and behavior in patients taking antibiotics causes some pathogenic bacteria become resistant. Increased bacterial resistance to antibiotics encourages applications as biocontrol phage to reduce pathogenic bacteria ...
Iswadi Iswadi
doaj +1 more source
Dental Caries, and Supragingival Plaque and Calculus among Students, Tanga, Tanzania. [PDF]
The prevalence of dental caries and supragingival plaque and calculus in 785 secondary schools students was assessed. More than half (53.6%) of the students were caries-free, and the majority of those with dental caries experience were aged 14-17 (68.1%)
Kabulwa, M.N. +3 more
core +1 more source
Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang +6 more
wiley +1 more source
A comprehensive method for quantifying human cytomegalovirus plaque assays
Human cytomegalovirus (hCMV) is an important human pathogen accounting for significant morbidity in immunocompromised individuals from neonates to cancer patients.
Laurel E. Kelnhofer-Millevolte +8 more
doaj +1 more source
Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7
Prime Editor 7‐mediated conversion of APOE4 to APOE3 alleviates Alzheimer's disease‐associated pathology in AD mouse models and patient‐derived neurons and improves cognitive performance in vivo, supporting therapeutic genome editing as a promising strategy for APOE4‐associated neurodegeneration.
Yunkyung Kim +16 more
wiley +1 more source
Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang +5 more
wiley +1 more source
Development of a robust cell-based potency assay for a coxsackievirus A21 oncolytic virotherapy
Oncolytic viruses (OV) are part of a burgeoning field of investigational oncolytic therapy (OT), in which lytic viruses dissolve advanced tumors productively and specifically.
Venkateswarlu Chamcha +6 more
doaj +1 more source
Quantification of RSV Infectious Particles by Plaque Assay and Immunostaining Assay
One of the most commonly used approaches for determining the quantity of infectious RSV particles in a given sample is the plaque assay. RSV infectious particles can be quantified by various direct and indirect methods.
Jorquera, Patricia A. +3 more
core +1 more source
Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du +10 more
wiley +1 more source
Estudo da incidência de adenovírus humano e suíno, norovírus humano e circovírus suíno, em amostras de água de consumo e descedentação animal do município de Concórdia, Santa Catarina [PDF]
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.Os dejetos provenientes da suinocultura e da população podem potencialmente contaminar mananciais de captação de água para consumo, já que esses efluentes ...
Garcia, Lucas Ariel Totaro
core

