Results 71 to 80 of about 39,266 (270)

"I don't want to manage it, I want to get rid of it" : a narrative analysis of living with chronic plaque psoriasis, and an investigation into vitamin D as a treatment : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Nutritional Science at Massey University, Albany, New Zealand [PDF]

, 2017
As a chronic skin disease, plaque psoriasis can cause significant psychosocial, emotional and physical burden. Psoriasis sufferers perceive others as lacking understanding around what it is like to live with this condition, and there has been little ...
Ingram, Michelle Anne
core  

Virus-Like Particle-Mediated Vaccination against Interleukin-13 May Harbour General Anti-Allergic Potential beyond Atopic Dermatitis [PDF]

, 2020
Virus-like particle (VLP)-based anti-infective prophylactic vaccination has been established in clinical use. Although validated in proof-of-concept clinical trials in humans, no VLP-based therapeutic vaccination against self-proteins to modulate chronic
Foerster, John, Molęda, Aleksandra
core   +2 more sources

Experimental Validation of an Immune Cell Infiltration Signature in Psoriasis: Translating Computational Modeling to In Vivo Efficacy

Journal of Clinical Laboratory Analysis, EarlyView.
We calculated the infiltration profiles of 28 immune cells within psoriatic immune microenvironment through single‐sample gene set enrichment analysis (ssGSEA) algorithm based on the eleven psoriasis related microarray datasets. Five immune‐related genes CXCL8, CXCL9, CCL18, RGS1, and SAMSN1 are associated with psoriasis, and establish a predictive ...
Tingjin Zheng, Rong Xu, Jianming Zhang, Xiujuan Wen, Hao Huang, Hongfeng Tang, Zhishan Zhang, Chong Zeng   +7 more
wiley   +1 more source

Association of Toll-like receptor 4 (TLR4) with chronic plaque type psoriasis and psoriatic arthritis. [PDF]

, 2016
Family studies have provided overwhelming evidence for an underlying genetic component to psoriasis. Toll-like receptors (TLRs) are key transmembrane proteins in both the innate and adaptive immune responses which are known to be integral processes in ...
A Korber, A Strange, A. Barton, BN Howie, BS Baker, C Wohn, C. E. M. Griffiths, E Begon, H. L. Hébert, H. Marzo-Ortega, J. Bowes, J. Massey, J. Worthington, JC Barrett, KJ Zhu, LC Tsoi, LD Sun, N Karaca, N. J. McHugh, NC Arbour, P. Ho, PE Stuart, R. B. Warren, Rh. Ll. Smith, S Garcia-Rodriguez, S Purcell, SJ Bielinski, T Hirai, Wellcome Trust Case Control Consortium, X Shen, Y Horie   +30 more
core   +5 more sources

Surveying immune and inflammatory alterations in periodontitis among individuals with Down syndrome: A preliminary cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background Individuals with Down syndrome (DS) are particularly vulnerable to early‐onset and rapidly progressing periodontitis, yet the local immune‐inflammatory alterations that contribute to this susceptibility are not fully understood. This study aimed to characterize cytokine profiles in gingival crevicular fluid (GCF) from individuals ...
Leticia Helena Theodoro, João Victor Soares Rodrigues, Marta A. A. Nuernberg, Pedro Henrique Petrilli, Mabelle de Freitas Monteiro, Valdir Gouveia Garcia, Rafael Scaf de Molon, Renato Correa Viana Casarin   +7 more
wiley   +1 more source

Infliximab in the treatment of plaque type psoriasis

Clinical, Cosmetic and Investigational Dermatology, 2009
Rosita Saraceno, Andrea Saggini, Lucia Pietroleonardo, Sergio ChimentiDepartment of Dermatology, University of Rome Tor Vergata, Rome, Viale Oxford 81, Rome, ItalyAbstract: Psoriasis is a chronic and immunomediated skin disease characterized by ...
Rosita Saraceno, Andrea Saggini, Lucia Pietroleonardo, Sergio Chimenti   +3 more
doaj  

Narrow-band UVB phototherapy does not consistently improve quality of life in psoriasis patients: A prospective observational study from Eastern India

Indian Dermatology Online Journal, 2018
Introduction: Psoriasis is a chronic inflammatory and proliferative condition of the skin which is well-known to impair the patients' quality of life (QoL).
Shweta Arora, Bikash R Kar
doaj   +1 more source

Leukocytoclastic vasculitis and necrobiotic pulmonary nodules in endoscopic remission of ulcerative colitis

JPGN Reports, EarlyView.
Abstract Skin and lung findings, including the rare findings of leukocytoclastic vasculitis (LCV) and necrobiotic pulmonary nodules, are known extraintestinal manifestations (EIMs) of inflammatory bowel disease. However, these rare EIMs have typically been reported as being a sign of active intestinal disease.
Joshua D. Noe, James Bistolarides, Karolyn A. Wanat, Yvonne Chiu   +3 more
wiley   +1 more source

Long-term follow-up of 22 psoriatic patients treated with ixekizumab after failure of secukinumab [PDF]

, 2020
Switching of biologic agents in treatment of plaque psoriasis is a common strategy. Only a few studies are available on switching between IL17A-blockers.
Amschler, K, Gerdes, S, Mohr, J, Mössner, R, Phillip, S, Poortinga, S, Wilsmann-Theis, D   +6 more
core   +1 more source

CD1a expression in psoriatic skin following treatment with propylthiouracil, an antithyroid thioureylene [PDF]

, 2003
BackgroundThe antithyroid thioureylenes, propylthiouracil (PTU) and methimazole (MMI), are effective in the treatment of patients with plaque psoriasis. The mechanism of action of the drugs in psoriasis is unknown.
Alan N Elias, Vandana S Nanda, Ronald J Barr, KG Linden, MW Greaves, HS Javitz, AN Elias, AN Elias, AN Elias, AN Elias, K Kose, G Aust, MK Gupta, LD Kohn, LD Kohn, N Ohtani, R Wilson, AN Elias, BJ Nickoloff, K Hong, J Cheng, PS Friedmann, J Czernielewski, RS Dawe, MA de Rie, M Tamura, S Athanasas-Platsis, JL Jones, JM Dobmeyer, DG Albertson, F Calabi, EM Beckman, T Fredriksson, P Asawanonda, O Larko, S Ebner, C Caux, AS Breathnach, T Plath, FO Nestle, A Lenz, J Czernielewski, J Kanitakis   +42 more
core   +1 more source