LncRNAs as Regulators of Atherosclerotic Plaque Stability [PDF]
Cells, 2023 Current clinical data show that, despite constant efforts to develop novel therapies and clinical approaches, atherosclerotic cardiovascular diseases (ASCVD) are still one of the leading causes of death worldwide.
Aleksa Petkovic +10 more
doaj +6 more sources
Exosomal circSCMH1/miR-874 ratio in serum to predict carotid and coronary plaque stability [PDF]
Frontiers in Cardiovascular Medicine, 2023 BackgroundTo investigate the correlation between lg (circSCMH1/miR-874) and acute coronary syndrome (ACS), acute myocardial infarction (AMI), and carotid plaque stability.Methods701 patients were divided into stable coronary artery disease (SCAD), ACS ...
Jiayu Wang +8 more
doaj +2 more sources
Gut Microbiota and Atherosclerosis—Focusing on the Plaque Stability [PDF]
Frontiers in Cardiovascular Medicine, 2021 Cardiovascular diseases (CVDs) are major causes of mortality and morbidity in the modern society. The rupture of atherosclerotic plaque can induce thrombus formation, which is the main cause of acute cardiovascular events.
Xinyi Shen +6 more
doaj +2 more sources
Inflammation-Related MicroRNAs Are Associated with Plaque Stability Calculated by IVUS in Coronary Heart Disease Patients [PDF]
Journal of Interventional Cardiology, 2019 Objectives. This study aimed to investigate the association between inflammation-related microRNAs (miR-21, 146a, 155) and the plaque stability in coronary artery disease patients. Methods.
Guo-fu Zhu +7 more
doaj +2 more sources
The Role of Hydrogen Sulfide in Plaque Stability [PDF]
Antioxidants, 2022 Atherosclerosis is the greatest contributor to cardiovascular events and is involved in the majority of deaths worldwide. Plaque rapture or erosion precipitates life-threatening thrombi, resulting in the obstruction blood flow to the heart (acute ...
Qian Lin, Bin Geng
doaj +2 more sources
Frontiers in Physiology, 2021 Macrophage polarization plays a vital impact in triggering atherosclerosis (AS) progression and regression. Huang-Lian-Jie-Du Decoction (HLJDD), a famous traditional Chinese decoction, displays notable anti-inflammatory and lipid-lowering effects in ...
Yinhe Cai +11 more
doaj +2 more sources
The “angiogenesis-plaque stability paradox” in atherosclerosis pathogenesis [PDF]
Frontiers in Cardiovascular MedicineIntraplaque angiogenesis, a critical mechanism in the pathological progression of atherosclerosis (AS), exhibits a paradoxical role by providing nutrients and repair support for plaques while simultaneously contributing to plaque instability and rupture.
Fei Yan, Si-yang Sun, Hong Wu
doaj +2 more sources
Neutrophil-specific STAT4 deficiency attenuates atherosclerotic burden and improves plaque stability via reduction in neutrophil activation and recruitment into aortas of Ldlr−/− mice [PDF]
Frontiers in Cardiovascular Medicine, 2023 Background and aimsNeutrophils drive atheroprogression and directly contribute to plaque instability. We recently identified signal transducer and activator of transcription 4 (STAT4) as a critical component for bacterial host defense in neutrophils. The
W. Coles Keeter +10 more
doaj +2 more sources
The Value of Lp-PLA2 as a Biomarker for the Diagnosis of Plaque Stability in Atherosclerosis: A Meta-Analysis [PDF]
Clinical and Applied Thrombosis/HemostasisBackground & Objective: Lipoprotein-associated phospholipase A2 (Lp-PLA2), secreted by inflammatory cells within atherosclerosis lesions, has emerged as a promising biomarker linked to plaque stability.
Ting Huang MS, Baocheng Zhu MS
doaj +2 more sources
Impact of Food Exposome on Atherosclerotic Plaque Stability: Metabolomic Insights from Human Carotid Endarterectomy Specimen. [PDF]
Int J Mol SciDoche E +10 more
europepmc +3 more sources