Inhibition of PFKFB3 Hampers the Progression of Atherosclerosis and Promotes Plaque Stability [PDF]
Aims6-phosphofructo-2-kinase/fructose-2,6-biphosphatase (PFKFB)3-mediated glycolysis is pivotal in driving macrophage- and endothelial cell activation and thereby inflammation.
Kikkie Poels+16 more
doaj +2 more sources
Individuality, stability, and variability of the plaque microbiome [PDF]
Dental plaque is a bacterial biofilm composed of a characteristic set of organisms. Relatively little information from cultivation-independent, high-throughput analyses has been published on the temporal dynamics of the dental plaque microbiome. We used
Daniel R. Utter+4 more
doaj +4 more sources
Validating human and mouse tissues commonly used in atherosclerosis research with coronary and aortic reference tissue: similarities but profound differences in disease initiation and plaque stability. [PDF]
van Dijk RA+6 more
europepmc +2 more sources
Interventional hepatic apoC-III knockdown improves atherosclerotic plaque stability and remodeling by triglyceride lowering. [PDF]
Ramms B+10 more
europepmc +3 more sources
Retraction Note: Down-regulation of microRNA-342-5p or Up-regulation of Wnt3a Inhibits Angiogenesis and Maintains Atherosclerotic Plaque Stability in Atherosclerosis Mice. [PDF]
Sun H+8 more
europepmc +3 more sources
Assessment of Carotid Plaque Stability Using Contrast-Enhanced Ultrasound and Its Correlation With the Expression of CD147 and MMP-9 in the Plaque. [PDF]
Huang S+7 more
europepmc +3 more sources
Extensive lipid lowering, thickness of the fibrous caps, and plaque stability. [PDF]
Goto S, Goto S.
europepmc +2 more sources
Platelet-derived growth factor B (PDGF-B) is a mitogenic, migratory and survival factor. Cell-associated PDGF-B recruits stabilizing pericytes towards blood vessels through retention in extracellular matrix.
Renée J. H. A. Tillie+8 more
doaj +1 more source
Angiogenesis contributes to plaque instability in atherosclerosis and further increases cardio-cerebrovascular risk. Circular RNAs (circRNAs) are promising biomarkers and potential therapeutic targets for atherosclerosis.
Rong Yuan+6 more
doaj +1 more source
YKL40 potentially via activating the P38 pathway in decreasing atherosclerotic plaque stability. [PDF]
Wang C+7 more
europepmc +2 more sources