Results 21 to 30 of about 160,587 (337)

Ginsenoside Rb1 Enhances Plaque Stability and Inhibits Adventitial Vasa Vasorum via the Modulation of miR-33 and PEDF

Frontiers in Cardiovascular Medicine, 2021
Background: Atherosclerosis is closely associated with proliferation of the adventitial vasa vasorum, leading to the atherosclerotic plaque progression and vulnerability.
Xiaoyan Yang, Xiaoyan Yang, Lei Wang, Zihao Zhang, Jiayi Hu, Xiaoling Liu, Hao Wen, Hao Wen, Minghao Liu, Minghao Liu, Xue Zhang, Xue Zhang, Hongyan Dai, Mei Ni, Rui Li, Rong Guo, Lei Zhang, Xiaorong Luan, Huili Lin, Mei Dong, Huixia Lu   +20 more
doaj   +1 more source

Stabilization of high-risk plaques [PDF]

Cardiovascular Diagnosis and Therapy, 2016
The prevalence of atherosclerotic cardiovascular diseases (ASCVDs) is increasing globally and they have become the leading cause of death in most countries. Numerous experimental and clinical studies have been conducted to identify major risk factors and effective control strategies for ASCVDs.
Kohei, Takata, Satoshi, Imaizumi, Bo, Zhang, Shin-Ichiro, Miura, Keijiro, Saku   +4 more
openaire   +2 more sources

Chronic Stress A Potential Suspect Zero of Atherosclerosis: A Systematic Review

Frontiers in Cardiovascular Medicine, 2021
Atherosclerosis (AS) is a chronic vascular inflammatory disease, in which the lipid accumulation in the intima of the arteries shows yellow atheromatous appearance, which is the pathological basis of many diseases, such as coronary artery disease ...
Ling-bing Meng, Ling-bing Meng, Yuan-meng Zhang, Yue Luo, Tao Gong, De-ping Liu, De-ping Liu   +6 more
doaj   +1 more source

miR-150-5p affects AS plaque with ASMC proliferation and migration by STAT1

Open Medicine, 2021
We explore miR‐150‐5p in atherosclerosis (AS). The AS model was constructed using Apo E−/− mice with an injection of the miR-150-5p mimic or an inhibitor.
Bian Yuan, Cai Wenqiang, Lu Hongying, Tang Shuhong, Yang Keqin, Tan Yan   +5 more
doaj   +1 more source

Author Correction: Gene silencing of TACE enhances plaque stability and improves vascular remodeling in a rabbit model of atherosclerosis. [PDF]

Sci Rep, 2022
Zhao X, Kong J, Zhao Y, Wang X, Bu P, Zhang C, Zhang Y.   +6 more
europepmc   +3 more sources

Plaque stability and plaque regression: new insights [PDF]

European Heart Journal Supplements, 2006
Patients with prior cardiovascular disease and/or diabetes are at the highest risk of a myocardial infarction or stroke. Thus, the majority of morbid cardiovascular events arise in the large population of patients with qualifying risk factors, according to standard risk factor scoring techniques.
Diethelm Tschoepe, Bernd Stratmann
openaire   +1 more source

Stabilization of atherosclerotic plaques: an update [PDF]

European Heart Journal, 2013
The majority of coronary thrombi (∼75%) is caused by plaque rupture .1,2 Prototype of the rupture-prone plaque contains a large, soft, lipid-rich necrotic core with a thin and inflamed fibrous cap, so-called thin-cap fibroatheroma (TCFA) ( Figure 1 ).3,4 Other common features include expansive remodelling, large plaque size, plaque haemorrhage ...
Yla-Herttuala, S., Bentzon, J.F., Daemen, M., Falk, E., Garcia-Garcia, H.M., Herrmann, J., Hoefer, I., Jauhiainen, S., Jukema, J.W., Krams, R., Kwak, B.R., Marx, N., Naruszewicz, M., Newby, A., Pasterkamp, G., Serruys, P.W.J.C., Waltenberger, J., Weber, C., Tokgozoglu, L., ESC Working Grp Atherosclerosis Va   +19 more
openaire   +9 more sources

Clinical Utility of the Serum Level of Lipoprotein-Related Phospholipase A2 in Acute Ischemic Stroke With Cerebral Artery Stenosis

Frontiers in Neurology, 2021
We aimed to study the clinical utility of serum lipoprotein-associated phospholipase A2 (Lp-PLA2) in acute ischemic stroke (AIS) with cerebral artery stenosis (CAS). We included 200 AIS patients and 90 healthy controls in this study.
Jing Cao, Ping Yan, Yajun Zhou, Xia Zhou, Zhongwu Sun, Xiao-Qun Zhu   +5 more
doaj   +1 more source

Atherosclerotic carotid plaque composition: a 3T and 7T MRI-histology correlation study [PDF]

, 2016
Background and Purpose Carotid artery atherosclerotic plaque composition may influence plaque stability and risk of thromboembolic events, and non-invasive plaque imaging may therefore permit risk stratification for clinical management.
Condon, B., Foo, S.Y., Forbes, K.P., Holmes, W.M., Lopez Gonzalez, M.R., Muir, K.W., Stewart, W., Welch, G.   +7 more
core   +1 more source

Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis

Cells, 2019
The presence of mast cells in human atherosclerotic plaques has been associated with adverse cardiovascular events. Mast cell activation, through the classical antigen sensitized-IgE binding to their characteristic Fcε-receptor, causes the release ...
Eva Kritikou, Marie A.C. Depuydt, Margreet R. de Vries, Kevin E. Mulder, Arthur M. Govaert, Marrit D. Smit, Janine van Duijn, Amanda C. Foks, Anouk Wezel, Harm J. Smeets, Bram Slütter, Paul H.A. Quax, Johan Kuiper, Ilze Bot   +13 more
doaj   +1 more source