Results 31 to 40 of about 162,485 (319)

Klotho protects against chronic kidney disease-associated atherosclerotic plaque vulnerability in

open access: yesDi-san junyi daxue xuebao, 2020
Objective To explore the effects of chronic kidney disease (CKD) on the instability of atherosclerotic plaques and investigate the role of Klotho in this pathological process.
BI Xianjin   +4 more
doaj   +1 more source

HDL and plaque regression in a multiphase model of early atherosclerosis [PDF]

open access: yes, 2023
Atherosclerotic plaques are accumulations of cholesterol-engorged macrophages in the artery wall. Plaque growth is initiated and sustained by the deposition of low density lipoproteins (LDL) in the artery wall. High density lipoproteins (HDL) counterbalance the effects of LDL by accepting cholesterol from macrophages and removing it from the plaque. In
arxiv   +1 more source

Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis

open access: yesCells, 2019
The presence of mast cells in human atherosclerotic plaques has been associated with adverse cardiovascular events. Mast cell activation, through the classical antigen sensitized-IgE binding to their characteristic Fcε-receptor, causes the release ...
Eva Kritikou   +13 more
doaj   +1 more source

Triglyceride-Glucose Index Is Related to Carotid Plaque and Its Stability in Nondiabetic Adults: A Cross-Sectional Study

open access: yesFrontiers in Neurology, 2022
BackgroundCarotid plaque plays an important role in the development of stroke. The triglyceride-glucose (TyG) index is a reliable alternative marker of insulin resistance.
Anran Wang   +12 more
doaj   +1 more source

Huang-Lian-Jie-Du Decoction Attenuates Atherosclerosis and Increases Plaque Stability in High-Fat Diet-Induced ApoE-/- Mice by Inhibiting M1 Macrophage Polarization and Promoting M2 Macrophage Polarization

open access: yesFrontiers in Physiology, 2021
Macrophage polarization plays a vital impact in triggering atherosclerosis (AS) progression and regression. Huang-Lian-Jie-Du Decoction (HLJDD), a famous traditional Chinese decoction, displays notable anti-inflammatory and lipid-lowering effects in ...
Yinhe Cai   +11 more
doaj   +1 more source

Update of the CLRP eye plaque brachytherapy database for photon-emitting sources [PDF]

open access: yes, 2021
Purpose: To update and extend the Carleton Laboratory for Radiotherapy Physics (CLRP) Eye Plaque (EP) dosimetry database for low-energy photon-emitting brachytherapy sources using egs_brachy, an open-source EGSnrc application. The previous database, CLRP_EPv1, contained datasets for the Collaborative Ocular Melanoma Study (COMS) plaques (2008). The new
arxiv   +1 more source

Improving segmentation of calcified and non-calcified plaques on CCTA-CPR scans via masking of the artery wall [PDF]

open access: yesSPIE 12465, Medical Imaging 2023: Computer-Aided Diagnosis, 2022
The presence of plaques in the coronary arteries is a major risk to the patients' life. In particular, non-calcified plaques pose a great challenge, as they are harder to detect and more likely to rupture than calcified plaques. While current deep learning techniques allow precise segmentation of real-life images, the performance in medical images is ...
arxiv   +1 more source

The Complementary Effects of Dabigatran Etexilate and Exercise Training on the Development and Stability of the Atherosclerotic Lesions in Diabetic ApoE Knockout Mice

open access: yesPharmaceuticals, 2023
Aim: To determine the complementary effects of dabigatran etexilate (DE), exercise training (ET), and combination (DE + ET) on the development and stability of the atherosclerotic lesions in diabetic apoE knockout (apoE−/−) mice. Methods: In 48 male apoE−
Nikolaos PE Kadoglou   +5 more
doaj   +1 more source

Protease-Activated Receptor-2 Deficiency Attenuates Atherosclerotic Lesion Progression and Instability in Apolipoprotein E-Deficient Mice

open access: yesFrontiers in Pharmacology, 2017
Inflammatory mechanisms are involved in the process of atherosclerotic plaque formation and rupture. Accumulating evidence suggests that protease-activated receptor (PAR)-2 contributes to the pathophysiology of chronic inflammation on the vasculature. To
Pengfei Zuo   +6 more
doaj   +1 more source

Endothelial-to-Mesenchymal Transition in Atherosclerosis: Friend or Foe?

open access: yesCells, 2022
Despite many decades of research, complications of atherosclerosis resulting from the rupture or erosion of unstable plaques remain the leading cause of death worldwide.
Sarin Gole   +4 more
doaj   +1 more source

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