Results 51 to 60 of about 160,587 (337)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 Background NK2 homeobox 5 (Nkx2‐5) is a cardiac homeobox transcription factor that is expressed in a broad range of cardiac sublineages. Embryos lacking Nkx2‐5 are nonviable attributed to growth retardation and gross abnormalities of the heart.
Meng Du +10 more
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Birth of homoclinic intersections: a model for the central dynamics of partially hyperbolic systems [PDF]
, 2010 We prove a conjecture of J. Palis: any diffeomorphism of a compact manifold can be C1-approximated by a Morse-Smale diffeomorphism or by a diffeomorphism having a transverse homoclinic intersection.
Crovisier, Sylvain
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Ultrasound IMT measurement on a multi-ethnic and multi-institutional database: Our review and experience using four fully automated and one semi-automated methods [PDF]
, 2012 Automated and high performance carotid intima-media thickness (IMT) measurement is gaining increasing importance in clinical practice to assess the cardiovascular risk of patients. In this paper, we compare four fully automated IMT measurement techniques
Andrew Nicolaides +10 more
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Journal of Lipid Research, 2010 We recently reported that oxidized LDL (oxLDL) induces an oscillatory increase in intracellular calcium ([Ca2+]i) levels in macrophages. Furthermore, we have shown that these [Ca2+]i oscillations mediate oxLDL's ability to inhibit macrophage apoptosis in
Johnny H. Chen +5 more
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Strategies to achieve coronary arterial plaque stabilization [PDF]
Cardiovascular Research, 1999 Acute coronary syndromes result from fissure, erosion or rupture of a vulnerable atherosclerotic plaque. The characteristics of a vulnerable plaque include a large lipid pool, an abundance of inflammatory cells and mediators, a reduced smooth muscle cell and collagen content and a thin overlying fibrous cap.
R, Rabbani, E J, Topol
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Effects of platelet microparticles on atherosclerotic plaque formation and stability in ApoE-/- mice
Di-san junyi daxue xuebao, 2019 Objective To investigate the effect of platelet microparticles (PMPs) from C57BL/6 mice on atherosclerotic plaque formation and plaque stability in apolipoprotein E knockout (ApoE-/-) mice.
WANG Zeyang +4 more
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Oxidative Stress and Coronary Plaque Stability [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2002 Increased production of reactive oxygen species (ROS) in the vascular wall is a characteristic feature of disease states, including atherosclerosis, diabetes and hypertension. ROS, such as superoxide, reduce nitric oxide bioactivity by scavenging and cause oxidation of lipids and target proteins. In addition, recent work has revealed that ROS mediate a
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Frontiers in NeurologyBackgroundCarotid plaque instability is a critical determinant of ischemic stroke risk. Identifying ultrasound imaging features associated with plaque vulnerability may enhance stroke risk stratification.MethodsThis retrospective cohort study evaluated ...
Bo Wang, Yingjun Li, LiSha Qiu
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Journal of Lipid Research, 2013 Lysophosphatidic acid (LPA), a bioactive lysophospholipid, accumulates in the atherosclerotic plaque. It has the capacity to activate mast cells, which potentially exacerbates plaque progression.
Martine Bot +9 more
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Frontiers in Neurology, 2022 BackgroundCarotid atherosclerosis, especially the rupture of unstable plaques, plays an important role in the development of stroke. A novel lipid ratio, the non-high-density lipoprotein cholesterol (non-HDL-C)/high-density lipoprotein cholesterol (HDL-C)
Anran Wang +13 more
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