Results 61 to 70 of about 162,485 (319)

Strategies to achieve coronary arterial plaque stabilization [PDF]

open access: yesCardiovascular Research, 1999
Acute coronary syndromes result from fissure, erosion or rupture of a vulnerable atherosclerotic plaque. The characteristics of a vulnerable plaque include a large lipid pool, an abundance of inflammatory cells and mediators, a reduced smooth muscle cell and collagen content and a thin overlying fibrous cap.
Ramin Rabbani, Eric J. Topol
openaire   +3 more sources

Microstructure, Mechanical Properties, and Antibacterial Performance of Novel Fe‐Mn‐Zn Nanocrystalline Alloys Produced by Mechanical Alloying

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents the development of Fe‐Mn‐Zn nanocrystalline alloys (0–9 wt% Zn) by mechanical alloying and subsequently hot pressing. Their microstructure, density, hardness, wear resistance, corrosion behavior, and antibacterial properties are systematically examined.
Ilker Emin Dag   +3 more
wiley   +1 more source

Inflammation-Related MicroRNAs Are Associated with Plaque Stability Calculated by IVUS in Coronary Heart Disease Patients

open access: yesJournal of Interventional Cardiology, 2019
Objectives. This study aimed to investigate the association between inflammation-related microRNAs (miR-21, 146a, 155) and the plaque stability in coronary artery disease patients. Methods.
Guo-fu Zhu   +7 more
doaj   +1 more source

Carotid plaque age is a feature of plaque stability inversely related to levels of plasma insulin. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: The stability of atherosclerotic plaques determines the risk for rupture, which may lead to thrombus formation and potentially severe clinical complications such as myocardial infarction and stroke.
Sara Hägg   +11 more
doaj   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Clinical significance of macrophage phenotypes in cardiovascular disease

open access: yesClinical and Translational Medicine, 2014
The emerging understanding of macrophage subsets and their functions in the atherosclerotic plaque has led to the consensus that M1 macrophages are pro‐atherogenic while M2 macrophages may promote plaque stability, primarily though their tissue repair ...
Heather J Medbury   +2 more
doaj   +1 more source

Bifurcation analysis of a free boundary model of plaque formation associated with the cholesterol ratio [PDF]

open access: yesarXiv, 2020
The low-density lipoprotein (LDL)/high-density lipoprotein (HDL)-cholesterol ratio has been shown a high correlation with the cardiovascular risk assessment. Is it possible to quantify the correlation mathematically? In this paper, we develop a bifurcation analysis for a mathematical model of the plaque formation with a free boundary in the early stage
arxiv  

Parallel Network with Channel Attention and Post-Processing for Carotid Arteries Vulnerable Plaque Segmentation in Ultrasound Images [PDF]

open access: yesarXiv, 2022
Carotid arteries vulnerable plaques are a crucial factor in the screening of atherosclerosis by ultrasound technique. However, the plaques are contaminated by various noises such as artifact, speckle noise, and manual segmentation may be time-consuming.
arxiv  

Temperature‐Enhanced Supramolecular Polymer Adhesion Provided by Concurrent Utilization of Calix[4]Pyrrole and Crown Ether Molecular Recognition

open access: yesAdvanced Functional Materials, EarlyView.
Simultaneous utilization of calix[4]pyrrole‐ and crown ether‐based molecular recognition allows the construction of a high molecular weight alternating supramolecular polymer. This heat processible polymer can be used as a durable and reusable adhesive on glass and steel with temperature‐enhanced adhesion strength without the need for a solvent ...
Deniz Memis, Abdullah Aydogan
wiley   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

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